Key Responsibilities: Design and execute experiments supporting downstream process development (DSP) Perform protein purification using: AKTA chromatography systems Tangential Flow Filtration (TFF) / UF/DF Harvest centrifugation and filtration Apply Design of Experiments (DOE) for process optimization Support scale-up activities from bench to pilot and manufacturing scale Develop scale-down models and assess process robustness Analyze and interpret data; identify trends and process improvements Collaborate with cross-functional teams (MSAT, Manufacturing, Analytical, QA) Support technology transfer to GMP manufacturing Assist in process characterization, validation, and documentation Present findings and contribute to team discussions Key Requirements and Technology Experience: BS degree + 2+ years of relevant experience OR MS degree + 0+ years of relevant experience Degree in Biochemistry, Chemical/Biochemical Engineering, Chemistry, or related field Hands-on experience in downstream process development (NOT upstream) Strong experience with: AKTA chromatography systems UF/DF or Tangential Flow Filtration (TFF) Chromatography (Protein A, IEX, HIC preferred) Experience with: Process scale-up (bench pilot manufacturing) Scale-down models and process robustness Design of Experiments (DOE) Experience with Antibody Drug Conjugates (ADC) Knowledge of cGMP and technology transfer Experience in biologics (mAbs, bispecifics, fusion proteins) Familiarity with analytical methods (SEC/HPLC, CE, HCP) Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners.