Sr. Research Associate, Translational

Aspen is looking for a Sr. Research Associate, Translational to support the advancement of neuroscience programs from discovery through preclinical development. The ideal candidate can independently design and execute complex in vivo and ex vivo studies, analyze and interpret data, and contribute to translational strategy and program decision-making with minimal supervision. This is an on-site role in Torrey Pines, California; relocation is not available.

DUTIES AND RESPONSIBILITIES:

• Perform small animal stereotaxic neurosurgery, pre- and post-operative animal care, necropsy, and basic animal husbandry.
• Independently design, execute, and analyze in vivo and ex vivo studies, including rodent dosing, behavioral assays, biofluid (blood, CSF) and tissue collection.
• Perform post-mortem plasma and serum extraction, brain tissue processing, and moderately complex histological procedures including immunohistochemistry (colorimetric & fluorescent).
• Histological imaging, moderately complex quantification & data analysis using multiple platforms pertinent to translational neuroscience research (e.g., Cell Profiler, Visiopharm, ImageJ, Zen).
• Manage basic IHC pipeline workflow, material resources, and maintenance of high-throughput microscopy platform supporting Aspen R&D programs.
• Perform data analysis and visualization using tools like Excel, Prism, Python, R, etc.
• Assist with or perform in vitro studies for iPSC culturing, immunocytochemistry, flow cytometry and others
• Assist with or perform molecular biology routine assays (DNA/RNA extractions, PCR, library prep, etc.)
• Make detailed observations, compile, and file records with R&D department, maintain data on results of analysis and communicate results to supervisor and larger group of R&D scientists.
• Maintain general Translational Sciences lab inventory and organization of basic lab supplies, equipment, and reagents.
• Assist chemical safety representative for Translational Sciences department coordinating all hazardous waste generation, containment, and removal.

EDUCATION AND EXPERIENCE:

• Bachelor’s degree in biology, biochemistry, or a related discipline required.
• Minimum of three (3) years of experience working in central nervous system focused laboratory required.
• Working experience in a human pluripotent stem cell focused laboratory and/or delivering cell and gene products to the brain highly preferred.

JOB SPECIFICATIONS:

• Technical Proficiency: Advanced hands-on expertise in in vivo rodent handling and experimental procedures, including basic stereotaxic surgery, tissue collection, and execution of translational studies.
• Specialized Equipment Operation: Ability to independently operate, maintain, and troubleshoot specialty laboratory equipment, including histology microtomes, stereotaxic apparatus, surgical tools, and rotometry or motor testing systems.
• Translational Research & Histology Expertise: Moderate to advanced experience with histology, tissue processing, and imaging-based applications supporting translational and preclinical research.
• In Vivo Behavioral Testing: Experience with in vivo behavioral or motor testing assays (e.g., rotometry) preferred.
• Analytical Skills: Strong analytical and quantitative skills with the ability to interpret complex datasets, assess data quality, and draw conclusions that inform project decisions.
• Data Analysis & Presentation: Ability to efficiently organize, analyze, and present experimental data in a concise, accurate, and timely manner.
• Communication Skills: Excellent written and oral communication skills to clearly document experiments and communicate results to scientific and cross-functional audiences.
• Organization: Strong organizational and documentation skills, including the ability to independently maintain complete, accurate, and audit-ready lab notebooks and records.
• Collaboration & Adaptability: Strong collaboration skills with the ability to work effectively with colleagues from diverse backgrounds and cultures, adapt to a fast-paced environment, and adjust workload based on changing corporate and departmental priorities.
• Professional Conduct & Leadership: Ability to lead by example, promote company culture, and routinely interact with and mentor team members in support of team effectiveness and knowledge sharing.
• Technology: Proficiency with Microsoft Office applications, including Word, Excel, and PowerPoint.
• Travel: Ability to travel within U.S. up to approximately 10%.

WORKING CONDITIONS

Office and Lab environment. While performing the duties of this Job, the employee is frequently exposed to toxic or caustic chemicals. This is an indoor position requiring the ability to perform experiments in the laboratory, and type and use a computer.

EEO and Employment Eligibility:

Aspen Neuroscience is committed to providing equal employment opportunities to all employees and job applicants and prohibits discrimination and harassment of any type. We are committed to creating an inclusive environment for all employees. Aspen is not able to provide visa sponsorship for this role. Applicants must have valid work authorization that does not require employer sponsorship now or in the future.

Total Rewards and Culture:

Aspen Neuroscience, Inc., located in scenic Torrey Pines, is noted for its collaborative and learning focused culture where each person is valued for contributing their strengths and energy to building a world-class line of products for patients in need. The company offers a competitive total compensation package, time-off in addition to Company observed holidays, Medical/Dental insurance benefits, onsite gym, and other wellness perks.

The anticipated salary range for candidates who will work in San Diego is $81,000-$100,000 annually. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the industry, education, etc.  Aspen Neuroscience is multi-state employer, and this salary range may not reflect positions that work in other states.