NewPrincipal Scientist- NMR Spectroscopy Pace Analytical Life SciencesPrincipal Scientist- NMR SpectroscopyCary, NC$110,000–$120,000 / yearLeads biomolecular NMR characterization of protein and oligonucleotide samples, including sample handling and preparation, assessment of suitability and stability, execution of multidimensional NMR experiments, and application of testing requirements and orthogonal characterization workflows to support structure confirmation, method development, and data interpretation. The Principal Scientist serves as the technical authority for NMR instrumentation and data interpretation, leads complex investigations, supports client engagement and cross‑functional initiatives, and mentors scientists through innovation, scientific rigor, and collaboration.
NewPrincipal Mechanical Engineer JobotPrincipal Mechanical EngineerSan Jose, CA$200,000–$260,000 / yearInformation collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. Founded by industry veterans from leading aerospace and satellite organizations, the company has rapidly grown into a team of over 200 engineers, scientists, and innovators focused on building next-generation space infrastructure.
Principal Construction Project Engineer Naval Nuclear LaboratoryPrincipal Construction Project EngineerIdaho Falls, ID$106,200–$166,000 / yearBachelors degree from an accredited college or university in a related technical, engineering, science or construction field and a minimum of 9 years of relevant experience; or Masters degree from an accredited college or university in a related technical, engineering, science or construction field and a minimum of 7 years of relevant experience; or Doctorate degree from an accredited college or university in a related technical, engineering, science or construction field and a minimum of 3 years of relevant experience; or Currently a Principal Reactor Training Engineer, Refueling Engineer, or Field (RPCO) Engineer at the Company. Naval Nuclear Laboratory personnel are FMP employees who work at four DOE facilities: Bettis Atomic Power Laboratory, Knolls Atomic Power Laboratory, Kenneth A. Kesselring Site, and Naval Reactors Facility, and at the U.S. Department of Defense-owned Nuclear Power Training Unit-Charleston.
NewDistinguished Scientist ZillowDistinguished ScientistRemote, ORRemote$270,700–$432,300You will design agent architectures, memory and supervision frameworks, and learning strategies that allow our agents to build and maintain context-rich relationships over weeks and months, not just single sessions, while remaining trustworthy, compliant, and measurably helpful. Own the end-to-end research and technical strategy for long-horizon agentic experiences across shopping, financing, and professional workflows, in close partnership with the Agentic AI, data platform, and product teams.
Chief Scientist, EO/IR Technologies LeidosChief Scientist, EO/IR TechnologiesSan Diego, CA$154,050–$278,475The ideal candidate is comfortable engaging in deeply technical discussions to develop new solutions, working with experts across multiple fields, and is motivated to lead research teams to demonstrate disruptive capabilities for space. Doctorate in Engineering, Physics, Optics, or a related field with 13+ years of prior relevant experience in leading research programs in advanced sensors or Masters with 15+ years of prior relevant experience.
NewPrincipal Engineer of Radiological Work Naval Nuclear LaboratoryPrincipal Engineer of Radiological WorkNiskayuna, NY$106,200–$166,000 / yearBachelors degree from an accredited college or university in a related technical, engineering or science field and a minimum of 9 years of relevant experience; or Masters degree from an accredited college or university in a related technical, engineering or science field and a minimum of 7 years of relevant experience; or Doctorate degree from an accredited college or university in a related technical, engineering, science field and a minimum of 3 years of relevant experience; or Currently a Principal Reactor Training Engineer, Refueling Engineer, or Field (RPCO) Engineer at the Company. Naval Nuclear Laboratory personnel are FMP employees who work at four DOE facilities: Bettis Atomic Power Laboratory, Knolls Atomic Power Laboratory, Kenneth A. Kesselring Site, and Naval Reactors Facility, and at the U.S. Department of Defense-owned Nuclear Power Training Unit-Charleston.
Mechanical Engineer (Principal) Naval Nuclear LaboratoryMechanical Engineer (Principal)Charleston, SC$106,200–$166,000 / yearJoin the Site Engineering (SE) team as a Principal Mechanical Engineer in the Moored Training Ship Directorate/Site Projects, Planning, and Engineering (SPPE) Subdivision supporting engineering and maintenance of site infrastructure, utilities, and MTS support systems as well as the planning, design, and execution of facility improvements and construction projects at Nuclear Power Training Unit Charleston (NPTU-C). Engineer, Refueling Engineer, or Field (RPCO) Engineer at the Company; or Masters degree from an accredited college or university in a related technical, engineering or science field and a minimum of 7 years of relevant experience; or a Doctorate degree from an accredited college or university in a related technical, engineering, or science field with a minimum of 3 years of relevant experience.
Principal Mechanical Engineer Naval Nuclear LaboratoryPrincipal Mechanical EngineerWest Milton, NY$106,200–$166,000 / yearBachelors degree from an accredited college or university in a related technical, engineering or science field and a minimum of 9 years of relevant experience; or Masters degree from an accredited college or university in a related technical, engineering or science field and a minimum of 7 years of relevant experience; or Doctorate degree from an accredited college or university in a related technical, engineering, science field and a minimum of 3 years of relevant experience; or Currently a Principal Reactor Training Engineer, Refueling Engineer, or Field (RPCO) Engineer at the Company. Naval Nuclear Laboratory personnel are FMP employees who work at four DOE facilities: Bettis Atomic Power Laboratory, Knolls Atomic Power Laboratory, Kenneth A. Kesselring Site, and Naval Reactors Facility, and at the U.S. Department of Defense-owned Nuclear Power Training Unit-Charleston.
Principal Project Manager Naval Nuclear LaboratoryPrincipal Project ManagerWest Mifflin, PA$106,200–$166,000 / yearp>The position requires close interaction and coordination with other project managers, engineers, and management across multiple sites and organizations to ensure successful completion of project objectives, including close collaboration with stakeholder across NNL, BPMI, Naval Reactors, and sub-tier suppliers. Naval Nuclear Laboratory personnel are FMP employees who work at four DOE facilities: Bettis Atomic Power Laboratory, Knolls Atomic Power Laboratory, Kenneth A. Kesselring Site, and Naval Reactors Facility, and at the U.S. Department of Defense-owned Nuclear Power Training Unit-Charleston.
NewPrincipal IC Design Engineer, Analog MSEI US - Micro Systems EngineeringPrincipal IC Design Engineer, AnalogLake Oswego, ORDesign of novel, robust, ultra-low power, low-voltage analog/mixed-signal IC functional blocks including but not limited to voltage/current references, operational amplifiers, comparators, switched-capacitor circuits (amplifiers, filters, charge pumps, etc.), ADCs and DACs, oscillators, switching power circuits, communication circuits, etc. Active involvement in all aspects of IC design, including the development of functional concepts and specifications, top-level design architecture, design partitioning and block level design, detailed circuit design and simulation, layout floor-planning and transistor level layout, bench verification and testing, test-vector development, and documentation.
NewPrincipal Engineer - Python API Development Fidelity InvestmentsPrincipal Engineer - Python API DevelopmentColleyville, TXRemote$107,000–$216,000Please be advised that Fidelity’s business is governed by the provisions of the Securities Exchange Act of 1934, the Investment Advisers Act of 1940, the Investment Company Act of 1940, ERISA, numerous state laws governing securities, investment and retirement-related financial activities and the rules and regulations of numerous self-regulatory organizations, including FINRA, among others. You will design, build, and evolve reliable, secure, and cost‑efficient platform capabilities—from model packaging and serving to observability and lifecycle management—working closely with multiple teams to ensure these capabilities are practical, robust, and widely usable in production.
NewSr. Advisor - Global Technical Services Molecule Steward - Dry Products LillySr. Advisor - Global Technical Services Molecule Steward - Dry ProductsIndianapolis, IN$117,000–$209,000Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Serve as Manufacturing TS/MS (Technical Services/Manufacturing Science) representative to integrate the commercialization work plans across Product Development, CM&C teams, Manufacturing sites, and applicable functional areas to commercialize new solid oral dosage forms.
Principal Scientist (M.D. or D.O.) ExponentPrincipal Scientist (M.D. or D.O.)Bellevue, WAFull timeLeveraging deep knowledge in medicine to address a wide range of complex human health challenges across diverse client sectors, therapies, clinical health endpoints, and patients, delivering scientifically rigorous and impactful solutions. For over five decades, we've connected the lessons of past failures with tomorrow's solutions to advise clients as they innovate technologically complex products and processes, ensure the safety and health of their users, and address the challenges of sustainability.
Principal Data Scientist, Pricing Strategy OKTAPrincipal Data Scientist, Pricing StrategyBellevue, WAFull timeNotice for New York City Applicants & Employees: Okta may use Automated Employment Decision Tools (AEDT), as defined by New York City Local Law 144, that use artificial intelligence, machine learning, or other automated processes to assist in our recruitment and hiring process. You'll combine strong quantitative rigor with strategic thinking to design measurement approaches, build and operationalize models, and run test-and-learn pilots that inform high-impact monetization programs.
Principal Data Scientist (AI Agent/Agentic) Visa Usa IncPrincipal Data Scientist (AI Agent/Agentic)Bellevue, WAFull timeVisa is a world leader in payments and technology, with over 259 billion payments transactions flowing safely between consumers, merchants, financial institutions, and government entities in more than 200 countries and territories each year. Advises on technical specifications during discussions with collaborators (e.g., Product owners, business partners, Cybersecurity) to identify and clarify sophisticated technical or business requirements and identify business needs and upstream and/or downstream system/application dependencies.
Biomarkers Senior Principal Research Scientist Vertex Pharmaceuticals IncorporatedBiomarkers Senior Principal Research ScientistSeattle, WAFull timeThe Biomarkers Senior Principal Research Scientist is an independent leader with advanced scientific knowledge and expertise in biomarker development who develops and implements the clinical biomarker strategy for one or more programs and implements the biomarker plan during clinical development with minimal guidance. Works cross-functionally to ensure that assays are developed and validated according to regulatory guidance and are ready in time for clinical use, along with providing supportive written documentation of assay characteristics and validation.
Principal Facilities Engineer Company ConfidentialPrincipal Facilities EngineerIdaho Falls, ID$106,200–$166,000 / yearFull time
Principal Project Analyst Company ConfidentialPrincipal Project AnalystIdaho Falls, ID$95,700–$149,600 / yearFull time
Principal Civil Engineer Company ConfidentialPrincipal Civil EngineerNiskayuna, NY$106,200–$166,000 / yearFull time
Electrical Systems and Controls Engineer (Principal) Company ConfidentialElectrical Systems and Controls Engineer (Principal)West Mifflin, PA$117,900–$184,300 / yearFull time
Principal AI/ML Engineer - 27560 Company ConfidentialPrincipal AI/ML Engineer - 27560Annapolis Junction, MD$133,555–$175,000Full time7 years relevant experience with Bachelors in related field; 3 years relevant experience with Masters in realted field; 0 years experience with PhD or Juris Doctorate in related field; or High School Diploma or equivalent and 12 years relevant experience. HII, Mission Technologies has a need for an AI/ML Engineer who will be responsible for designing advanced model architectures, developing machine learning pipelines, and optimizing AI systems for operational deployment in government and mission critical environments.
Principal Identity, Credential, and Access Management (ICAM) Architect Company ConfidentialPrincipal Identity, Credential, and Access Management (ICAM) ArchitectSpringfield, VAFull time5 years relevant experience with Bachelors in related field; 3 years relevant experience with Masters in related field; 0 years experience with PhD or Juris Doctorate in related field; or High School Diploma or equivalent and 9 years relevant experience. Our workforce includes skilled tradespeople; artificial intelligence, machine learning (AI/ML) experts; engineers; technologists; scientists; logistics experts; and business administration professionals.
Principal Scientist (Director) - Regulatory Affairs-CMC Merck & Co IncPrincipal Scientist (Director) - Regulatory Affairs-CMCNorth Wales, PA$190,800–$300,300 / yearThe Principal Scientist / Director responsibilities include but are not limited to: • Serve as a Regulatory CMC Project Lead and provide CMC Regulatory leadership within Regulatory and on cross-functional teams for the assigned biological products in development or commercial products. Under general supervision of an Executive Director/Senior Director, the Principal Scientist /Director is responsible for developing and implementing Chemistry, Manufacturing, and Controls (CMC) regulatory strategies for our organizations biologics product franchises in accordance with domestic and international regulations and guidance.
Principal Scientist - Translational Biology & Program Leadership WuXi Biologics Cayman IncPrincipal Scientist - Translational Biology & Program LeadershipNatick, MA$95,000–$155,000 / yearJob Summary: We are seeking a strategic and scientifically driven Principal Scientist with strong expertise in translational immunology, ex vivo biology, and therapeutic program leadership to lead cross-functional drug discovery initiatives across oncology, autoimmune, and inflammatory disease programs. In addition to technical expertise in ex vivo immune assays and complex 3D model systems, the ideal candidate will possess demonstrated experience leading multidisciplinary discovery teams, coordinating program activities across functions, and influencing strategic direction in a fast-paced biotechnology environment.
Principal Scientist Histocompatibility Lab Versiti, Inc.Principal Scientist Histocompatibility LabMilwaukee, WisconsinFull timeThis combination of skill and knowledge results in improved patient outcomes, higher quality services and reduced cost of care for hospitals, blood centers, hospital systems, research and educational institutions, and other health care providers. Based on training progression and competency the Principal Scientist will be expected to apply for ASHI Director In-Training (DIT) status and ACHI Board Certification (required for PhD candidates) and subsequently obtain full ASHI and ACHI Director Certifications per an outlined DIT plan.
Principal AI Product Manager, Technical T-Mobile USA, IncPrincipal AI Product Manager, TechnicalBellevue, WAFull timeDay to day activities or responsibilities include: conducting market research; writing features or user stories; determining specifications; defining long-term strategy of the product; creating the product road map; driving technical delivery end to end; defining scope for releases/product increments; partnering with development, project/program management, marketing, and other key stakeholders to define release schedule; and support/drive go-to-market activities as needed. Product Manager, Technical is the ultimate "jack-of-all-trades" leveraging deep customer empathy, strategic thinking, commercial, analytical, technical capability and knowledge, and leadership prowess to successfully deliver delightful and differentiated products that drive growth and positively impact customers lives.
Principal Engineer, Public Cloud / R&D Core Cloudera Government SolutionPrincipal Engineer, Public Cloud / R&D CoreSeattle, WARemoteFull timeBachelor's degree in Computer Science or equivalent, and 10+ years of experience; OR Master's degree and 6+ years of experience; OR PhD and 4+ years of experienceDistributed Systems Visionary: You have 10+ years of experience building and scaling robust products. Architectural Leadership: Serve as the primary technical lead, independently driving the design and architecture of complex, large-scale cloud services that underpin our multi-cloud and hybrid data management platform.
Principal Engineer - Grid Analytics & Technology Solutions Puget Sound Energy, IncPrincipal Engineer - Grid Analytics & Technology SolutionsClyde Hill, WAFull timeServing as a technical leader and primary point of integration between power system engineering, data science, and backend tooling, this role ensures that modeling tools, datasets, automated workflows, and system integrations effectively support forwardlooking analysis, scenario evaluation, and informed decision making. This role provides technical authority and direction across backend data management, database administration, GIS integration, automation, and system integration to ensure that modeling tools and supporting applications areaccurate, reliable, scalable, and aligned withlongtermplanning needs.
NewPrincipal Scientist I, II or III - Purification Chemist - FSP Parexel International CorpPrincipal Scientist I, II or III - Purification Chemist - FSPNJFor results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement. Apply knowledge and skillsets in chromatography, organic chemistry, or biochemistry to execute the purification of API, reaction products, process intermediates, byproducts, or impurities in an R&D laboratory.
Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThe Principal Scientist will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic and establish Moderna as a leader in antibody and de novo binder design for in vivo delivery. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Director / Principal Scientist, Biologics Drug Substance Commercialization (BDSC) Merck & Co IncDirector / Principal Scientist, Biologics Drug Substance Commercialization (BDSC)West Point, PA$173,200–$272,600 / yearRequired Skills: Antibody Therapeutics, Biologics, Cell Cultures, Clinical Manufacturing, Commercialization, Cross-Functional Collaboration, Cross-Functional Teamwork, Downstream Processing, Mammalian Cell Culture, Manufacturing Scale-Up, Process Characterization, Process Control, Technology Transfer, Upstream Process Development. Within Our Company's Manufacturing Division, Biologics Drug Substance Commercialization (BDSC) provides upstream process leadership and laboratory capabilities that advance late-stage pipeline and commercial drug substance manufacturing for biologics.
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting) NovartisPrincipal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management. Candidates with demonstrated impact as a modeler, preferably in the pharmaceutical/biotech industry, and with commensurate experience and proficiency may be considered for the Principal Scientist II (3+ years) or Senior Principal Scientist (5+ years) role.
NewSenior Principal Scientist I, Lab Head, Protein Engineering SanofiSenior Principal Scientist I, Lab Head, Protein EngineeringCambridge, MA$148.50–$214.50 / hourAs Lab Head, you will help drive the evolution of Sanofi's next-generation antibody engineering platforms by integrating structure-guided design, high-throughput experimental technologies, protein language models, computational modeling, and AI/ML-enabled engineering approaches into biologics discovery workflows. Serve as the Protein Engineering representative on cross-functional project teams, collaborating with Therapeutic Areas and partner functions to define engineering strategies, coordinate project activities, and support milestone progression.
Senior Director (Senior Principal Scientist), Translational Medicine, Immunology Merck & Co IncSenior Director (Senior Principal Scientist), Translational Medicine, ImmunologyBoston, MA$286,900–$451,600 / yearInterface broadly with key functions including Discovery Sciences, Preclinical Pharmacology, Pharmaceutical Sciences, Toxicology, Translational Biomarkers, Translational Medicine Operations, Translational Medicine-EU, Drug Metabolism/Modeling & Simulation, Regulatory Affairs, and late-stage Clinical Research throughout sites in the USA, UK and Belgium. Translational Medicine is specifically responsible for: • Contributing to the identification of novel targets by partnering with discovery research teams to bring a clinical insight into the earliest stages of target identification and validation, and executing clinical studies to evaluate the relevance of potential targets to human disease in order to justify investment in full development.
Senior/Principal Scientist, Formulation Development Forma Life SciencesSenior/Principal Scientist, Formulation DevelopmentIrvine, CaliforniaDescription About Forma Life Sciences Forma Life Sciences is a next-generation CDMO headquartered in Irvine, California, where molecules become medicine. Forma supports oral solid dosage programs from early clinical development through commercial manufacturing, with deep formulation expertise and cGMP manufacturing capabiliti...
NewSr. Principal Scientist (Sr. Director) - Regulatory Liaison Merck & Co IncSr. Principal Scientist (Sr. Director) - Regulatory LiaisonBoston, MA$190,800–$300,300 / yearRequired Skills: Biological Sciences, Clinical Reporting, Drug Development, Global Health, In Vitro Diagnostics (IVD), Multiple Therapeutic Areas, Pharmaceutical Regulatory Affairs, Process Improvements, Product Approvals, Regulatory Affairs Compliance, Regulatory Affairs Management, Regulatory Communications, Regulatory Compliance, Regulatory Issues, Regulatory Strategies, Regulatory Strategy Development, Written Communication. As the Global Regulatory Lead (GRL), the Senior Principal Scientist functions as the regulatory single, accountable, global point of contact on the project team and interacts with the global regulatory agencies and/or subsidiaries with regard to global regulatory strategy/registration requirements for one or more company investigational and marketed drugs/biologics in early- and/or late-stage development.
Associate Principal Scientist, Analytical R&D Merck & Co IncAssociate Principal Scientist, Analytical R&DRahway, NJ$142,400–$224,100 / yearJoin us and experience our culture firsthand - one of strong ethics & integrity, diversified experiences, exceptional science and a resounding passion for improving human health through innovative drug delivery technologies and predictive analytical tools. Your main responsibilities will include: Driving Pipeline: Leading or participating on analytical teams driving the development of drugs in the company's pipeline, with a deep understanding of product development from early stage through commercialization.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsThe Principal Scientist will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Associate Principal Scientist, Engineering Merck & Co IncAssociate Principal Scientist, EngineeringWest Point, PA$142,400–$224,100 / yearAccountabilities and Responsibilities for this position include but are not limited to the following: Leads and/or serves on cross functional biologics drug product (DP) working groups and manages DP activities through filing and Process Performance Qualification (PPQ), including registration stability study execution, process characterization plan and execution, tech transfer control strategy, process development, PPQ readiness, PAI (Pre‐Approval Inspection) readiness, approval, launch and post‐launch support. As part of Our Company's Manufacturing Division, the Sterile Drug Product Commercialization group provides the technical process leadership and laboratory capabilities for late stage and commercial drug product processes for biologics and combination products.
Associate Principal Scientist, Combination Product Design Verification (Associate Director Equivalent) Merck & Co IncAssociate Principal Scientist, Combination Product Design Verification (Associate Director Equivalent)Rahway, NJ$142,400–$224,100 / yearRequired Skills: Collaborative Development, Combination Products, Commercialization, Design Controls, Design Failure Mode and Effect Analysis (DFMEA), Design Verification Testing, Device Development, Human Factor Engineering, Manufacturing Processes, Mechanical Engineering, Mechanical Testing, Medical Device Quality Systems, Method Validation, Product Risk Management, Project Leadership, Quality Management Systems (QMS), Release Testing, Self Motivation, Testing Methodology, Test Method Validation, Test Procedure Development, Troubleshooting. This role has a primary focus on design verification while encompassing the full spectrum of testing activities, including test method development and validation, analytical transfers, incoming testing, in-process, release testing, and testing readiness to enable successful clinical introduction and commercialization.
Principal Scientist - Semiconductor Devices and Coatings Forge NanoPrincipal Scientist - Semiconductor Devices and CoatingsThornton, CO$130,000–$170,000Forge Nano Inc., a rapidly growing advanced materials company specializing in nano-scale coatings across diverse markets, is seeking a highly experienced Principal Scientist - Semiconductor Devices and Coatings to lead semiconductor application development and advance the TEPHRA technology roadmap. The Principal Scientist - Semiconductor Devices and Coatings will provide technical vision, lead complex cross-functional initiatives, and mentor scientific staff while contributing to business growth and external partnerships.
NewPrincipal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors Natera IncPrincipal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid TumorsCA$171,900–$214,950 / yearThe Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.
Applied Research Team Leader / Principal Engineer / Principal Scientist Applied Research Associates IncApplied Research Team Leader / Principal Engineer / Principal ScientistLittleton, COCandidates for this position should have experience in one or more of the following areas: • Performing engineering or applied physics research at a deep technical level • Performing R&D of novel prototype systems for defense-related applications • Experience transitioning from prototype technologies into fieldable systems • Design and development of systems with wireless connectivity and real-time embedded processing • Signal processing related to acoustic or optical real-time detection and classification • Implementation of machine learning and artificial intelligence on edge hardware systems. Applied Research Associates, Inc. (ARA) is seeking an experienced Principal Engineer or Principal Scientist with a proven ability to lead applied research programs and successfully secure funding to support and grow those efforts.
Sr. Principal/Principal Scientist Legend Biotech CorpSr. Principal/Principal ScientistSomerset, NJLegend Biotech is seeking a highly experienced Senior Principal Scientist / Principal Scientist - Flow Cytometry to provide scientific leadership and hands-on expertise in flow cytometry to support cell and gene therapy programs from IND-enabling studies through early- and late-stage clinical development. This role is critical for ensuring scientific rigor, data quality, and strategic insight across in-house and outsourced flow cytometry activities, including assay development, validation, CRO oversight, and deep data interpretation to support translational, PK/PD, and regulatory decision-making.
NewAssociate Principal Scientist, Sterile Drug Product Commercialization Merck & Co IncAssociate Principal Scientist, Sterile Drug Product CommercializationWest Point, PA$142,400–$224,100 / yearLead and/or serve on cross-functional biologics drug product (DP) working group and manage DP activities through filing and Process Performance Qualification (PPQ), including registration stability study execution, process characterization plan and execution, tech transfer control strategy, process development, PPQ readiness, PAI (Pre‐Approval Inspection) readiness, approval, launch, and post‐launch support. As part of our Manufacturing Division, the Sterile Drug Product Commercialization (SDPC) group provides technical process leadership and laboratory expertise for late‑stage and commercial sterile drug products, including vaccines, biologics, and pharmaceutical and combination products.
Principal Scientist III - Synthetic Chemist - FSP Parexel International CorpPrincipal Scientist III - Synthetic Chemist - FSPNJFor results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement. Experience in organic chemistry, organic synthesis, synthetic methodology, catalysis (including chemocatalysis, biocatalysis, and heterogeneous catalysis), total synthesis, physical organic chemistry, or flow chemistry.
Principal Scientist, Pharmacokinetics Merck & Co IncPrincipal Scientist, PharmacokineticsSouth San Francisco, CA$176,200–$277,300 / yearRequired Skills: ADME, Biochemical Analysis, Biophysics, Cross-Functional Teamwork, Detail-Oriented, Diversity and Inclusion (D&I), Drug Metabolism, Immunoassays, Innovation, Liquid Chromatography-Mass Spectrometry (LC-MS), Mentoring Staff, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, PKPD Modeling, Therapeutic Proteins. Key Responsibilities of the Principal Scientist: Project-team representative and subject matter expert for biologics drug discovery and development, including but not limited to drug conjugates, multi-specific biologics, and novel modalities.
Associate Principal Scientist, Molecular Modeling Merck & Co IncAssociate Principal Scientist, Molecular ModelingWest Point, PA$142,400–$224,100 / yearThe tools that we develop are as diverse as the teams developing them, and in this Associate Principal Scientist role, the successful candidate will leverage their expertise in atomistic modeling of drug substance and drug formulations with an ability to apply predictive sciences to support our Company's pipeline of antibodies, small molecules, peptides, biologics, conjugates, and vaccines. We aspire to embed digital technologies into the fabric of DSCS culture to drive transformational impact, by innovating solutions through strong partnership in the domains of Data Science, Data Analysis, Informatics, Multi-Omics, Predictive Science, and Data Engineering.
Principal Scientist, Technical Director - Process Engineering - Oral Solid Dosage, Clinical Manufacturing (Onsite) Merck & Co IncPrincipal Scientist, Technical Director - Process Engineering - Oral Solid Dosage, Clinical Manufacturing (Onsite)Rahway, NJ$173,200–$272,600 / yearPSCS #eligibleforERP #FLEx2026 #NSBE2026 Required Skills: Clinical Manufacturing, Creativity, Cross-Functional Teamwork, Decision Making, Downstream Processing, Driving Continuous Improvement, Manufacturing Scale-Up, Mentorship, Process Characterization, Process Control, Process Design, Process Optimization, Regulatory Submissions, Strategic Thinking, Technology Transfer Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Has knowledge of formulation science and in-depth knowledge in multiple areas, including core understanding of the drug development process, excipient attributes, and formulation-process interplay Demonstrated understanding of connectivity between clinical development, chemistry, manufacturing and control (CMC) and commercial marketing, balancing the needs of patients and ensuring successful launch of drug products Experience leading development projects at an enterprise level Strong mentoring capabilities to build individuals and teams.
Principal Scientist, R&D - Packaging Dev The Kraft Heinz CoPrincipal Scientist, R&D - Packaging DevGlenview, IL$104,200–$130,200 / yearThis role requires strong scientific thinking, sound technical judgment, and the ability to apply prior learning to new challenges, including right-sizing, material simplification, and cost-optimized pack formats. You will lead work from concept through commercialization by identifying business needs, designing and executing tests, analyzing data, drawing conclusions, and translating insights into viable packaging solutions.