1,267 Results for

Senior Scientist Jobs in Cambridge, MA

Jobs

Cambridge, MA

Clinical Scientist will ideally be familiar with drug development and regulatory requirements and will deploy this expertise in the execution of a number of key responsibilities:

Contributes to program team meetings, scientific advisory boards, study steering committees and data/safety monitoring meetings; may represent function in collaborative activities with other departments; Member of the Clinical Study Team and Global Clinical SubTeam.
Authors and/or reviews documents related to trials, such as medical monitoring plans, SAPs, informed consents and clinical components of the Clinical Study Reports with minimal guidance and supports the development of regulatory documents; performs quality review and may approve; adjudicate and resolve cross functional comments with minimal support.

4 days ago

Norwood, MA

$121,000–$173,000

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FM is seeking a Senior Research Scientist to develop new scientific knowledge, technologies, and engineering solutions to challenges in material flammability, fire dynamics, and fire protection, which can be used and applied by FM to help prevent or control property loss for insured clients. Job Description:

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners.

Today

Norwood, MA

$121,000–$173,000

The position will directly contribute to industrial property loss prevention, with emphasis on critical business areas and emerging hazards such as data centers, renewable energy industries, automated storage facilities, and operations involving ignitable liquids. Job Description:

Today

Norwood, MA

$121,000–$173,000

Job Description:

Research experience involving experimental heat transfer measurement, battery failure analysis, high-voltage battery system testing, such as BESS or UPS battery systems, is highly desirable.

Today

Marlborough, MA

strong>Analytical Characterization

Operate and maintain key analytical instruments such as GPC, HPLC, UPLC, NMR and related chromatography tools; perform routine calibrations and basic troubleshooting. Polymer & Organic Synthesis
- Perform hands-on polymer and/or organic synthesis of monomers, oligomers, and polymers at lab scale (typically 100 mL–20 L), following established procedures and safety protocols.

4 days ago

Cambridge, MA

This position provides opportunities to collaborate within the Therapeutics modalities department; the candidate is expected to execute multi-step processes independently and proactively and communicate progress effectively in oral and written communications. Demonstrate diligence in equipment maintenance, inventory tracking, and proactive ordering of laboratory supplies, and provide support for day-to-day laboratory management activities.

4 days ago

Waltham, MA

Remote

$60,000–$70,000 / year

Client is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world's greatest health challenges.

Demonstrate technical capacity to understand sales tools (Web, database, CRM, Order Management, reports).

4 days ago

Boston, MA

$152,600–$190,700 / year
Full time

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Join the fun and follow us on social media to see what's happening at our company, and don't forget to connect with us on Lennar: Overview | LinkedIn<https://www.linkedin.com/company/lennar/> for the latest job opportunities.

You’ll work alongside data scientists, AI engineers, and ML engineers—owning and shipping the most visible data and AI products in the company across pricing, forecasting, personalization, and emerging agentic AI use cases, deployed across 40+ divisions of one of the nation’s largest homebuilders.

23 days ago

Cambridge, MA

$112,304–$168,456 / year

Your work will be highly visible across global programs, with countless opportunities to learn, challenge assumptions, and collaborate across disciplines-all while contributing to therapies that make a clear, measurable difference for patients.

Innovation and Acceleration: Explore new excipients, chemistries, and scalable routes; where relevant, leverage automation and computational design to build smarter lipid libraries and shorten iteration time.

5 days ago

Marlborough, MA

Under the Associate Scientific Director, the Senior Scientist will use technical expertise of NGS/LRS biochemistry, understanding of sequencing data analysis, and genetics knowledge to autonomously conduct research project(s) under the umbrella of large initiatives within Quest's Specialty Genetics and Women's Health portfolios. Come join a collaborative team of laboratory and automation R&D scientists and partner with experts across Bioinformatics, IT, Variant Science, and other functions to develop the next generation of molecular diagnostic solutions.

18 days ago

Cambridge, MA

$130,000–$150,000 / year

p>Atavistik Bio is led by an experienced team of drug hunters with a proven track record of developing marketed small molecule therapies and supported by top-tier investors, including The Column Group, Nextech Invest, Lux Capital, Regeneron Ventures, and RA Capital Management.

Candidate Privacy Notice:

By submitting your resume/CV and any accompanying materials, you acknowledge and consent to the collection, processing, and storage of your personal information for the purpose of evaluating your candidacy, managing the recruitment process, and communicating with you regarding current or future opportunities.

30+ days ago

Lexington, MA

$145,000–$190,000 / year

p>Hands-on work involving highly complex activities; lead project (target, biology, or technology-related) involving coordination of multiple experimental activities & groups, recommends/is responsible for ensuring realistic project timelines & deliverables, work closely with project manager ; deep understanding of subject matter & demonstrates creative, independent thinking to identify & address disease/biology-related questions/gaps, potentially across therapeutic areas; represent NN at conferences & global meetings; may propose & lead external collaborations; author internal reports & external publications; recommend, present, & champion new targets or methodologies. Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at Novo Nordisk; & frequent interaction with project managers & other colleagues across global R&D.

2 days ago

Somerville, MA

$70–$90 / hour

In terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA.

We are seeking a Senior Scientist with deep expertise in hematology to lead the development of in vitro assays and stem/progenitor cell models that support dose‑setting, in vivo study design, and advancement of early‑stage therapeutic programs.

15 days ago

Plymouth, MA

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Direct experience with one or more: adhesives, composites, resin cements, GIC / RMGI, hydraulic cements, MTA, bioceramics, bioglass, silicates, zirconia, desensitizers, bioactive remineralization systems, or adjacent technologies.

Familiarity with relevant characterization and testing: rheology/viscosity, FTIR conversion, depth of cure, mechanical testing (flexural / compressive), water sorption / solubility, radiopacity, aging / thermocycling, ion release.

5 days ago

Cambridge, MA

p>In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Collaborate closely with computational and experimental scientists to align system design with biological questions, and partner with data engineering and technology teams to enable robust deployment and scaling while maintaining ownership of scientific modeling, data abstractions, and analytical design.

30+ days ago

Boston, MA

$160,000–$180,000 / year

Centessa is seeking a Senior Scientist in Discovery DMPK to partner with pharmacologists and medicinal chemists to support the identification of lead candidates with optimal DMPK properties for potential progression into development. Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts.

30+ days ago

$110,000–$185,000 / year

p>Bonus points for:

Experience with Python Must-have Requirements:

Perform activities such as typing or sitting for extended periods of time Willingness to travel or work required nights/weekends/on-call regularly Work in a facility that contains industrial hazards including heat, cold, noise, fumes, strong magnets, lead (Pb), high voltage, high current, pressure systems, and cryogenics. • Evaluate potential techniques and technologies to make the measurements required in ARC, with a particular focus on techniques that will work robustly in the thermal and radiological environment in ARCDetermine which techniques and technologies will require significant R&D and work with CFS R&D teams to scope out what projects are necessary to develop these technologies.

30+ days ago

South Boston, Massachusetts

The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia.

The ideal candidate possesses deep expertise in solid-phase synthesis, state of the art purification techniques, and analytical characterization, combined with a proven track record of mentoring junior scientists, leading cross-functional projects.

26 days ago

Cambridge, MA

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.

30 days ago

Cambridge, MA

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.

3 days ago

Cambridge, MA

li>Proven ability to develop novel computational methods that generate tractable biological insights from integrating complex datasets, balancing deep methodological innovation within individual data modalities with holistic integration across multimodal datasets, and translating results into testable hypotheses that inform target discovery, validation, or biomarker development.

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

30+ days ago

Cambridge Crossing, MA

$137,570–$166,706 / year

Proficient with molecular and cellular biology related techniques, including but not limited to 2D/3D/spheroid cell culture and related cellular assays, Western blot and/or JESS, qRT-PCR, flow cytometry, proliferation and/or cytotoxicity assays (CyQuant, CTG, apoptosis, IncuCyte, etc.), ELISA, MSD and/or HTRF assays, colony formation assay, processing of DNA/RNA/protein, IP/Co-IP. In addition, the individual will coordinate with other functions, such as informatics and predictive science, lead discovery and optimization, in vivo pharmacology, and translational research teams to design/execute work related to patient stratification, identification of appropriate PD markers and assay development/transfer for miniaturization, among others to ensure timely project advancement.

25 days ago

Cambridge, MA

$98,700–$183,300 / year

Provide mentorship and insights for junior associates to support advance method development for custom discovery PK and PKPD.Collaborate as a subject matter expert in bioanalysis with biotransformation, in vitro and in vivo colleagues, as well as chemists and biologists with project teams. Collaborate with our CRO partners for special case custom BA method transfers to the CRO.Utilizes established networks and builds new network connections, including outside of own department.

5 days ago

Waltham, MA

$50–$61 / hour

This role will lead in vitro target validation and functional characterization of engineered cell therapies, with a strong emphasis on CAR-T research, complex immunological assays, and data-driven program advancement. By applying for this job, you agree to receive calls, AI-generated calls, text messages, or emails from and its affiliates, and contracted partners.

6 days ago

Waltham, MA

strong> Key responsibilities

In vitro discovery : Lead cell therapy target validation and characterize activity of engineered cell therapies using human primary cells and functional co-culture assays; develop and optimize assays; preferred flexibility to additionally contribute to in vivo study design and execution in partnership with in vivo pharmacology. Required qualifications and skills
- Education : PhD in immunology, cell biology, or related field with 0-5 years experience; or BS or MS with 10+ years of experience in a related field (industry experience strongly preferred).

6 days ago

Cambridge, MA

$100.50–$145.17 / hour

PhD or PhD candidate in chemical engineering, mathematics, physics or related with expected graduation date by first semester of 2027 with 0+ years of experience academic experience will be considered) OR a master's degree in chemical engineering, mathematics, or physics or related with a minimum of 4 years of experience (academic experience will be considered) OR a bachelor's degree in chemical engineering, mathematics, or physics with a minimum of 8 years of experience. You will play a key role in implementing and scaling Model Predictive Control (MPC) systems, leveraging advanced process models to optimize performance in real-time, maintain product quality, and enhance operational efficiency across large-scale manufacturing environments.

30+ days ago

Cambridge, MA

$116,284–$174,426 / year

p>Required Skills:

Confirmed expertise in LC-MS (ThermoFisher Orbitrap, Agilent QTOF) and software platforms, including Protein Metrics Suite, BioPharma Finder and PEAKS, for intact mass deconvolution, peptide mapping analysis, post-translational modifications (PTMs), characterization of charge variants, and disulfide mapping. Reporting to the Associate Director of the Analytics & Mass Spec Group, the Senior Scientist will work closely with a multidisciplinary team to support various stages of our pipeline projects and give to the enhancement of our technology platforms through mass spectrometry and analytical techniques.

30+ days ago

Boston, MA

$119,100–$187,500 / year

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Communicate results clearly to project teams and the broader scientific community (internal reports, presentations, and publications), and uphold laboratory safety, animal welfare and regulatory compliance while collaborating across functions and with external partners.

Experience designing and executing sequencing studies (i.e. bulk RNAseq, scRNAseq or snRNAseq), working knowledge of data analysis tools (Python and/or RStudio preferred) and experience generating figures/reports.

5 days ago

Needham, MA

$155,000–$160,000 / year

This position collaborates with external manufacturing and tech transfer and is focused on Adenovirus and Herpesvirus vectors, associated cell-based potency assays, as well as performing training of new technical staff and troubleshooting and validation of new and established assays.

A strong background in one or more analytical techniques such as various HPLC based methods, microplate UV/Vis/Luminescent assays, cell-based assays including virus quantification and potency, qPCR, electrophoresis, sizing techniques such as DLS, etc.

6 days ago

Remote

$109,000–$174,800 / year

p>All Job Posting Locations:

Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

30+ days ago

Cambridge, MA

$132,330–$160,350 / year

p>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/.

3 days ago

Cambridge, MA

$117,600–$154,400 / year

For this position you'll need the following education, experience and skills:

Minimum Qualifications:

PhD in related field and/or several years of industrial laboratory-based LC/MS experience (biochemistry, chemistry, molecular & cellular biology, or biophysics) + 6-12 years' experience, BS or MS + 12-18 years' experience. Working in a multidisciplinary team you will apply your expertise to complement the biophysical and biochemical characterizations of recombinant proteins and communicate to stakeholders across the US research organization.

24 days ago

Cambridge, MA

p>Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

30+ days ago

Cambridge, MA

Proficiency and hands-on experience in applying a wide range of cellular and molecular biological methods (in particular: CRISPR, qRT-PCR, cloning, cell culture, cell viability/death assays, transient/stable cell line generation, immunoblotting, FACS) and softwares such as Microsoft Office, prism, spotfire. Additionally, the candidate will assess new state-of-the-art technologies and explore their potential for enhancing our ability to identify targets and create more accurate complex-disease models.

3 days ago

Needham, MA

A strong background in one or more analytical techniques such as various HPLC based methods, microplate UV/Vis/Luminescent assays, cell-based assays including virus quantification and potency, qPCR, electrophoresis, sizing techniques such as DLS, etc.  .

2 days ago

Cambridge, Massachusetts

p>The Senior Scientist, Analytical Chemistry will develop and deploy advanced analytical and characterization strategies to support Discovery Chemistry efforts across Lila’s platform, with a focus on enabling the rapid design, synthesis, screening, and optimization of small molecules and related molecular matter. The Senior Scientist will help build an integrated analytical capability spanning compound characterization, reaction monitoring, molecular profiling, and high-throughput data generation to support fast and iterative design–make–test–analyze cycles.

18 days ago

Somerville, MA

$127,000–$164,000 / year

p>The ideal candidate will bring deep hands-on expertise in cell and gene therapy (CGT) analytical development, a proven track record of successful assay troubleshooting and tech transfers, and the scientific rigor required to bridge the gap between early scientific assay development and commercial QC operations. This individual contributor role will be responsible for designing and executing internal analytical testing for process development, innovating and qualifying new analytical assays, and leading the end-to-end technical transfer of these methods to external QC laboratories.

5 days ago

Cambridge, MA

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Provide support, as needed, to clinical and commercial fill/finish manufacturing operations through process capability analysis, troubleshooting, root cause analysis, and product impact assessments for process changes/improvements and non-conformance investigations.

12 days ago

Waltham, MA

$151,000–$170,000 / year

p>Job Description:

We are seeking an enthusiastic and highly motivated Senior Scientist to join the Genomic Sciences and Target Discovery team within Alkermes R&D, focusing on the application of genome-editing technologies to validate therapeutic hypotheses in vitro and in vivo for central nervous system (CNS) disorders. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.

17 days ago

Cambridge, MA

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.

20 days ago

Cambridge, MA

$126,000–$181,500 / year

Lead the end-to-end design and construction of plasmid DNA constructs, including vector architecture, gene synthesis strategies, and high-efficiency cloning workflows (e.g., Gibson, Golden Gate, recombination-based methods). You will play a critical role in building scalable platforms for plasmid DNA design, construction, and optimization, leveraging automation, algorithm-driven sequence design, and data-centric workflows.

30+ days ago

South Boston, MA

$145,000–$155,000 / year

The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia.

25 days ago

Cambridge, MA

3 days ago

Cambridge, MA

$85.50–$123.50 / hour

In addition to overseeing day-to-day operations of cutting-edge automated systems, the candidate will play a pivotal role in shaping the strategic direction of the high-throughput expression platform, identifying opportunities for innovation, and championing cross-functional scientific initiatives across MEST and LMR (Antibody Discovery, Protein Production, and Protein Engineering). The successful candidate will serve as a scientific leader expert in ultra-high-throughput protein and antibody expression, driving the development and optimization of next-generation production platforms that support therapeutic candidates designed by state-of-the-art AI/ML models and structural biology.

30+ days ago

Cambridge, MA

$100.50–$145.17 / hour

p>Main responsibilities:

Experimental Design & Execution:
Design and perform experiments using bulk RNA-seq, single-cell/single-nucleus RNA-seq (sc/snRNA-seq), NGS and spatial assays (GeoMx, Visium, Xenium, Phenocycler-Fusion) on human and non-human biological samples. The ideal candidate will bring strong technical expertise in bulk RNA-seq, single-cell/single-nucleus RNA-seq (sc/snRNA-seq), spatial transcriptomics, and spatial proteomics to support a broad scope of research initiatives.

12 days ago

Cambridge, MA

$100.50–$145.17 / hour

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Integrate automation and robotics to scale workflows and improve reproducibility, including developing automated liquid handling protocols, implementing high-throughput imaging and data acquisition systems, and optimizing robotic platforms for multi-step differentiation processes. You will work proactively across multidisciplinary teams, lead ophthalmology drug discovery programs, influence project strategies, and mentor colleagues while driving innovation in disease modeling and therapeutic evaluation.

30+ days ago

Cambridge, MA

$119,100–$187,500 / year

Diverse Talent | We are committed to providing an inclusive and welcoming environment with supporting leadership behaviors because having a high-performing, engaged workforce is critical to our ability to deliver innovative solutions to patients and customers around the world. Expertise with multi-parameter flow cytometry, developing in vitro assays to investigate immune function and possess a deep knowledge of technologies commonly used to assess immune endpoints.

21 days ago

Boston, MA

$113,156–$149,750 / year

p>We seek a Senior Scientist skilled in lipid nanoparticle formulation, targeted delivery, synthesis and characterization of conjugated targeting ligands, plasma protein corona analysis and control, RNA/LNP physicochemical characterization, and in vitro/in vivo performance assessment, with a focus on elucidating and overcoming mechanistic nanoparticle delivery hurdles. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

20 days ago

Somerville, Massachusetts

4 days ago

Cambridge, Massachusetts

The current focus will be on release and stability management of oligonucleotide drug substances, drug products, and process intermediates (e.g., siRNA and conjugates). Your actual base salary will be based on several factors, including relevant skills, experience, internal equity, relevant education or training and market dynamics.

18 days ago

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Senior Scientist Jobs in Cambridge, MA

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