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Current projects in the lab include: (1) dissecting the acidic tumor microenvironment to develop novel acid-resistant immunocytokines for cancer immunotherapy; (2) utilizing a live tumor bank to identify predictive biomarkers of resistance to immune checkpoint inhibitors and to design immunotherapy strategies for unresponsive patients; and (3) deploying tumor-infiltrating lymphocytes and humanized tumorgraft mouse models with autologous immune systems to test novel immunotherapy approaches for localized drug delivery, improved efficacy, and reduced systemic toxicity. A postdoctoral training position is available in the laboratory of Dr. Tao Yue, in the Center for the Genetics of Host Defense at UT Southwestern Medical Center to study cancer immunology and generate a cutting-edge translational immunology platform for biomarker discovery and immunotherapy development.

University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - Center for the Genetics of Host Defense - Yue Lab

The Department of Biochemistry at UT Southwestern Medical Center invites applications for a Postdoctoral Research Fellow to join the laboratory of Dr. Chuo Chen. Our benefits are designed to support your overall wellbeing, and include: PPO medical plan, available day one at no cost for full-time employee-only coverage.

POSTDOCTORAL RESEARCHER - Biochemistry - Chen Lab

Our laboratory is interested in a wide variety of model systems and experimental approaches, including biochemistry, molecular biology, structural biology, animal models, genomics, proteomics, bioinformatics, and computational biology to uncover how signaling pathways control gene expression programs, spanning multiple interconnected areas: (1) signaling by NAD+ and steroid hormones; (2) ADP-ribosylation and the PARP enzymes that catalyze this modification in transcription, translation, chromatin dynamics, and RNA biology; (3) enhancer function and enhancer RNA regulation in gene activation; (4) RNA-based mechanisms in nuclear signaling and gene regulation; and (5) systems-level approaches to map signaling-gene regulation networks across the genome and transcriptome, with applications to cancer, metabolism, development, and a variety of human diseases. Expertise in next-generation sequencing approaches (e.g., RNA-seq, ChIP-seq), genome editing, or computational genomics is highly desirable.

POSTDOCTORAL RESEARCHER - Gene Regulation and Functional Genomics - Kraus Lab

Wang lab studies 1) oxidative stress / mitochondrial dysfunction-induced neurodegeneration and neuronal cell death in aging-related neurological diseases (Wang Y et al., A postdoctoral training position is available in the laboratory of Dr. Yingfei Wang in Departments of Pathology and Neurology at UT Southwestern Medical Center to study Alzheimer's disease and neurodegeneration.

POSTDOCTORAL RESEARCHER - Pathology - Wang Lab

The successful candidates will have demonstrated expertise in pulse sequence programming, image reconstruction, deep learning, and/or translational science, as evidenced by high-quality peer-reviewed publications. Ongoing projects include cardiovascular MRI applications in atrial fibrillation, pediatric heart disease, cardiac implantable electronic devices, and cardiotoxicity.

POSTDOCTORAL RESEARCHER - Cardiothoracic Imaging - Kim Lab

We interested in discovering novel interactions of host proteins that regulate autophagy with viral factors at the molecular level followed by mapping how these interactions impact cellular and mammalian host response to virus infection. Our laboratory has several exciting projects related to understanding how autophagy facilitates the clearances of virus particles and promotes immune activation in the central nervous system to improve cellular and organismal survival during virus infection.

Security Researcher Jobs in Dallas, TX

POSTDOCTORAL RESEARCHER - Center for the Genetics of Host Defense - Yue Lab University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - Biochemistry - Chen Lab University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - Gene Regulation and Functional Genomics - Kraus Lab University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - Pathology - Wang Lab University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - Cardiothoracic Imaging - Kim Lab University of Texas Southwestern Medical Center

POSTDOCTORAL RESEARCHER - IM (Infectious Disease) - Thinwa Lab University of Texas Southwestern Medical Center

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