Jordan Singer Yourth Enrichment Center Pre-K Director Manchester Boys Club Inc.Jordan Singer Yourth Enrichment Center Pre-K DirectorManchester, NHFull timeThe Pre-K Director is responsible for the creation, launch, and ongoing leadership of the BGCGM’s early childhood education program serving children ages 4 and 5 at the JSYEC. The Director ensures the program meets all applicable state childcare regulations and reflects the Club's mission of enabling all young people to reach their full potential.
Program Director Manchester Boys Club Inc.Program DirectorManchester, NHFull timeIs responsible for program marketing by working alongside the Director of Marketing, the Unit Director, and all program staff to ensure the promotion and marketing of programs and services for members are done promptly via posting of daily schedules, fliers, monthly newsletters, weekly announcements, and BGCGM social media. • Will serve as Assistant Camp Director for the summer day camp program, which will include working with the Unit Director on the hiring, training, scheduling, and evaluation of all summer program staff as well as program development.
NewAssistant Director of Nursing, RN Linden Ponds by Erickson Senior LivingAssistant Director of Nursing, RNWeymouth, MA$120,000–$150,000 / yearLocation: Linden Ponds by Erickson Senior Living Join our team as the Assistant Director of Nursing is responsible for clinical leadership and outcomes within our Skilled, Assisted Living, and Memory Care neighborhoods. See Erickson Senior Living Privacy Policy at https://www.ericksonseniorliving.com/privacy-policy and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions.
NewSafety Manager - Multifamily Construction JobotSafety Manager - Multifamily ConstructionBoston, MA$125,000–$150,000 / yearInformation collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. The Safety Manager oversees safety programs across multiple multifamily construction sites, working closely with site leadership to maintain a proactive safety culture.
Site Director at Nottingham West Elementary KinderCare EducationSite Director at Nottingham West ElementaryHudson, NHWhen you join our team as a Site Director, you will: Lead and supervise a group of teachers to create unique and engaging classroom experiences, leverage and develop “best in class” educators to be passionate and committed professionals. At KinderCare Learning Companies, the first and only early childhood education provider recognized with the Gallup Exceptional Workplace Award , we offer a variety of early education and child care options for families.
Before and After School Site Director at Anna Ware Jackson Primary KinderCare EducationBefore and After School Site Director at Anna Ware Jackson PrimaryPlainville, MA$20.25–$28.35When you join our team as a Site Director, you will: Lead and supervise a group of teachers to create unique and engaging classroom experiences, leverage and develop “best in class” educators to be passionate and committed professionals. At KinderCare Learning Companies, the first and only early childhood education provider recognized with the Gallup Exceptional Workplace Award , we offer a variety of early education and child care options for families.
Site Director at Prospect Hill Academy Charter Middle School Campus KinderCare EducationSite Director at Prospect Hill Academy Charter Middle School CampusCambridge, MA$20.25–$28.35When you join our team as a Site Director, you will: Lead and supervise a group of teachers to create unique and engaging classroom experiences, leverage and develop “best in class” educators to be passionate and committed professionals. At KinderCare Learning Companies, the first and only early childhood education provider recognized with the Gallup Exceptional Workplace Award , we offer a variety of early education and child care options for families.
Site Director at Henri A Yelle KinderCare EducationSite Director at Henri A YelleNorton, MA$20.25–$28.35When you join our team as a Site Director, you will: Lead and supervise a group of teachers to create unique and engaging classroom experiences, leverage and develop “best in class” educators to be passionate and committed professionals. At KinderCare Learning Companies, the first and only early childhood education provider recognized with the Gallup Exceptional Workplace Award , we offer a variety of early education and child care options for families.
Director of Social Services Care-OneDirector of Social ServicesNewton, MAEnsures and documents that residents/families have input into the care planning process; Acts as liaison between residents, families, outside agencies, and the Center Administrator to ensure that the resident's rights are maintained; Takes responsibility for conducting family meetings as needed; Functions in a management capacity and adheres to all policies and procedures of the Center as a representative of CareOne Administration; Performs administrative requirements such as completing necessary forms and reports under the direction of the Administrator and submitting such reports to the Administrator and/or consultants as required; Facilitates discharge planning including the development of an organized discharge plan for all customers; Concerns self with the safety of all Center residents in order to minimize the potential for fire and accidents. Also ensures that the Center adheres to legal, safety, health, fire, and sanitation codes by being familiar with his/her in carrying out the Center's fire, safety and disaster plans and by being familiar with current MSDS; Puts customer service first and adheres to the CareOne Culture of Excellence Pledge.
Assistant Director of Social Services Care-OneAssistant Director of Social ServicesNewton, MASocial Service functions include but are not limited to: supervising social service staff, direct services, advocacy, counseling, service coordination, education, in-servicing, policy and program development and community relations. The Assistant Director of Social Services will abide by and practice according to the company's Social Service Policies and Procedures Manual, State and Federal guidelines and the National Association of Social Workers' "Code of Ethics".
NewBusiness Development Director Encompass Health Rehabilitation Hospital of BraintreeBusiness Development DirectorDuxbury, MAIn this senior leadership role, you will be at the forefront of designing and implementing innovative referral programs, driving census growth and fostering a culture centered on patient safety and care excellence. You'll guide, train, and develop a dynamic Business Development team, all while creating strategies that align with our mission and deliver exceptional outcomes for patients, families and staff.
NewFacilities Management Director Encompass Health Rehabilitation Hospital of RichmondFacilities Management DirectorManchester, VAA minimum of five years of supervisory experience in healthcare-related facility equipment and systems operations, including expertise in chiller systems, steam boilers, hydraulic systems, building controls, electrical systems, and air handlers. Our achievements include being named one of the "World's Most Admired Companies" and receiving the Fortune 100 Best Companies to Work For® Award, among other accolades, which is nothing short of amazing.
NewArea Business Development Director Encompass Health Rehabilitation Hospital of RichmondArea Business Development DirectorManchester, VAThe Business Development Director is responsible in creating an environment and culture that enables the hospitals to fulfill their mission by meeting or exceeding goals, conveying the hospital mission to all staff, holding staff accountable for performance, motivating staff to continuously improve performance. The Area Business Development Director is responsible for inpatient and outpatient census of multiple hospitals through the design and implementation of referral programs and customer service strategies.
NewFacilities Management Director Encompass Health Rehabilitation Hospital of JohnstonFacilities Management DirectorCumberland, RIA minimum of five years of supervisory experience in healthcare-related facility equipment and systems operations, including expertise in chiller systems, steam boilers, hydraulic systems, building controls, electrical systems, and air handlers. Our achievements include being named one of the "World's Most Admired Companies" and receiving the Fortune 100 Best Companies to Work For® Award, among other accolades, which is nothing short of amazing.
Emergency Medicine Medical Director in Worcester, MA TeamHealthEmergency Medicine Medical Director in Worcester, MAWorcester, MA$359,200–$474,000 / yearFull timeThis role offers a balanced mix of hands-on clinical care and administrative leadership, with the opportunity to partner closely with hospital leadership to drive quality outcomes, operational efficiency, and patient experience initiatives. TeamHealth is seeking a board-certified emergency medicine physician to serve as medical director at the Saint Vincent Hospital emergency department in Worcester, MA.
Associate Director, Clinical Educator, Sickle Cell Disease (West Zone) - Remote Agios PharmaceuticalsAssociate Director, Clinical Educator, Sickle Cell Disease (West Zone) - RemoteBoston, MARemote$153,541–$230,312 / yearThe current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. The Regional Agios Clinical Educator Manager is a unique leadership opportunity, providing day to day oversight of 5-7 Agios Clinical Educators (ACEs) who interact directly with patients and healthcare professionals.
Associate Director, Field Marketer (Southwest) - Remote Agios PharmaceuticalsAssociate Director, Field Marketer (Southwest) - RemoteBoston, MARemote$153,541–$230,312 / yearThe current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities.
Director, Commercial Risk Evaluation and Mitigation Strategies (REMS) Lead - Remote Agios PharmaceuticalsDirector, Commercial Risk Evaluation and Mitigation Strategies (REMS) Lead - RemoteBoston, MARemote$183,549–$230,312 / yearThe Director leads the development, implementation, and ongoing management of commercial related REMS activities to support compliance, patient safety, and effective execution across sales, field marketing, patient support, specialty distribution and other customer-facing teams. The current base salary range for this position is expected to be between $183,549 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
Senior Director, Mid-Market Sales & Account Management - Remote MotiveSenior Director, Mid-Market Sales & Account Management - RemoteBoston, MARemoteMotive serves more than 120,000 customers – from Fortune 500 enterprises to small businesses – across a wide range of industries, including transportation and logistics, construction, energy, field service, manufacturing, agriculture, food and beverage, retail, and the public sector. Collaborate with Product, Sales, Onboarding, and Strategy leaders to identify customer needs, influence roadmap decisions, and design cohesive sales programs, incentive plans, and GTM strategies that connect across global functions for a seamless customer journey.
Director, Regulatory Strategy (Pediatrics) - Remote Agios PharmaceuticalsDirector, Regulatory Strategy (Pediatrics) - RemoteBoston, MARemote$183,549–$275,324 / yearThe current base salary range for this position is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. This individual will lead cross-functional teams in preparing and overseeing development of compliant, high quality, nonclinical and clinical global regulatory submissions to support development, registration, or life cycle management activities.
Director, Biostatistics - Remote Agios PharmaceuticalsDirector, Biostatistics - RemoteBoston, MARemote$183,000–$275,000 / yearThe current base salary range for this position is expected to be between $183,000 and $275,000 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. The Director will serve as the lead statistician for assigned clinical development programs, leading the development and implementation of statistical solutions to support all phases of clinical trials, regulatory filing and facilitating decision-making.
Director, Product Design - Remote MotiveDirector, Product Design - RemoteBoston, MARemote$187,000–$286,000 / yearA compelling online portfolio demonstrating a strong understanding of user-centered design principles, strategic thinking, leadership in driving design vision, problem-solving abilities, and the successful delivery of impactful user experiences and business outcomes. Motive serves more than 120,000 customers – from Fortune 500 enterprises to small businesses – across a wide range of industries, including transportation and logistics, construction, energy, field service, manufacturing, agriculture, food and beverage, retail, and the public sector.
Director, Sales Finance SamsaraDirector, Sales FinanceBoston, MARemoteThis is a high-visibility leadership role with exposure across senior leadership, and you will lead a team while working across Sales, Finance, Operations, Accounting, Legal, and Product to navigate complex commercial decisions. Samsara (NYSE: IOT) is the pioneer of the Connected Operations™ Cloud, which is a platform that enables organizations that depend on physical operations to harness Internet of Things (IoT) data to develop actionable insights and improve their operations.
Associate Director, Forecasting & Performance Analytics, Commercial Operations & Analytics - Remote Agios PharmaceuticalsAssociate Director, Forecasting & Performance Analytics, Commercial Operations & Analytics - RemoteBoston, MARemote$153,541–$230,312 / yearThe current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. Build, maintain, and evolve operational, unit-based forecasts across the portfolio – demand, revenue, and patient-based models – including scenario planning and risk and opportunity assessments for multiple launches and in-line products.
Associate Director, Scientific Communications & Publications - Remote Agios PharmaceuticalsAssociate Director, Scientific Communications & Publications - RemoteBoston, MARemote$153,000–$230,000 / yearOperating at the intersection of strategy and execution, this role partners closely with cross-functional colleagues and external experts to deliver high‑impact publications and scientific communications that advance both patient care and scientific dialogue. The current base salary range for this position is expected to be between $153,000 and $230,000 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
Regional Director, Enterprise East - Remote MotiveRegional Director, Enterprise East - RemoteBoston, MARemoteMotive serves more than 120,000 customers – from Fortune 500 enterprises to small businesses – across a wide range of industries, including transportation and logistics, construction, energy, field service, manufacturing, agriculture, food and beverage, retail, and the public sector. Motive is one of the fastest-growing software companies in the world, serving more than 120,000 businesses, across a wide range of industries including trucking and logistics, construction, oil and gas, food and beverage, field service, agriculture, passenger transit, and delivery.
Senior Scientist, Safety Assessment Prime Medicine, Inc.Senior Scientist, Safety AssessmentCambridge, MA$145,000–$177,000 / yearD. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Associate Director, Clinical Data Management Prime Medicine, Inc.Associate Director, Clinical Data ManagementCambridge, MA$174,000–$212,000 / yearPrime Medicine is seeking an experienced Associate Director of Clinical Data Management to lead clinical data strategy and execution across gene editing programs from first-in-human studies through regulatory submission. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Senior Enterprise Sales Director DoubleVerifySenior Enterprise Sales DirectorBoston, MABuilt on best practices, DV solutions create value for media buyers and sellers by bringing transparency and accountability to the market, ensuring ad viewability, brand safety, fraud protection, accurate impression delivery and audience quality across campaigns to drive performance. DV Rockerbox empowers marketers to confidently navigate the complexities of modern marketing measurement with a unified approach that combines Multi-Touch Attribution (MTA), Marketing Mix Modeling (MMM), and Testing.
Senior Director, Program Leader, Corporate Strategy Agios PharmaceuticalsSenior Director, Program Leader, Corporate StrategyCambridge, MA$229,562–$344,345 / yearDemonstrated ability to drive successful product launch and commercialization of innovative, first-in-class therapies, including lifecycle management (LCM) planning and execution; experience leading programs from late-stage development through commercial readiness and post-launch LCM strategies strongly desired. Define and continuously evolve the Target Product Profile, Clinical Development Plan, regulatory pathway, market access strategy, and commercial positioning in close partnership with cross-functional leaders and aligned with patient needs.
Associate Director, G&A Business Systems Analyst, IT Agios PharmaceuticalsAssociate Director, G&A Business Systems Analyst, ITCambridge, MA$153,541–$230,312 / yearCreate and deliver documentation required per established project implementation process for each phase of SDLC including but not limited to creating User requirements doc, system impact assessment, Test plan, Test scripts, traceability matrix, training plan, communications plan, end user guides, RAID logs, status reports, data migration plan, etc. Interact and support core G&A platforms including and not limited to Oracle HCM, Icertis CMS, Oracle Financials, Taleo ATS in a hybrid internal/vendor delivery model, partnering closely with IT Solutions Architect, PMO, and MSP.
Associate Director, Translational Medicine Agios PharmaceuticalsAssociate Director, Translational MedicineBoston, MA$153,541–$230,312 / yearThe current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities.
Senior Director, Search & Evaluation Waters CorporationSenior Director, Search & EvaluationMilford, MAThe Search & Evaluation (S&E) candidate will possess strong scientific expertise in the life sciences and relevant business development experience, as well as the strategic skills to architect and manage a portfolio of inorganic and partnering opportunities that complement Waters’ organic investments – building scientific and commercial leadership within the industry. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance.
NewSafety Manager Herc Rentals IncSafety ManagerBoston, MA$115,000–$145,000 / yearAssists the region at all levels with preparation and delivery of formal and informal safety training to Herc Rentals employees and customers at customer locations. Please be advised that the actual salary offered for any position is subject to the company's sole discretion and may be influenced by various factors, including but not limited to the candidate's qualifications, experience, location, and overall fit for the role.
NewTrauma Medical Director - Elliot Hospital, Manchester, NH (Tax-Free Living State and 1 hour to Boston) Elliot Health SystemTrauma Medical Director - Elliot Hospital, Manchester, NH (Tax-Free Living State and 1 hour to Boston)Manchester, TXWe are the only hospital in New England verified as a Comprehensive Hospital by the American College of Surgeons Quality Verification Program, and just the second in the country, to earn this highest-level designation for surgical quality and safety. Located in the heart of New England, Manchester is a thriving metropolitan community, located within an hour‘s drive of Boston, the seacoast, lakes region, and White Mountains of New Hampshire.
NewTrauma Medical Director - Elliot Hospital, Manchester, NH (Tax-Free Living State and 1 hour to Bosto Elliot Health SystemTrauma Medical Director - Elliot Hospital, Manchester, NH (Tax-Free Living State and 1 hour to BostoManchester, NHWe are the only hospital in New England verified as a Comprehensive Hospital by the American College of Surgeons Quality Verification Program, and just the second in the country, to earn this highest-level designation for surgical quality and safety. Located in the heart of New England, Manchester is a thriving metropolitan community, located within an hour's drive of Boston, the seacoast, lakes region, and White Mountains of New Hampshire.
NewMedical Director, Interventional Pain & Spine Center Beth Israel Lahey HealthMedical Director, Interventional Pain & Spine CenterBurlington, MA$485,000–$515,000 / yearCastro@lahey.org c/o Michael Kaufman, MD, Chair, Department of Anesthesiology & Interventional Pain Management and Dr. Zoher Ghogawala, MD, Chair, Division of Neurosurgery Beth Israel Lahey Health, including all of its employing entities, are a purpose-driven, values-based organization that unites our workforce of people who provide exceptional health care to everyone we serve. Clinical Leadership: Oversee patient care delivery and advance a full spectrum of pain services, including medication management, image-guided spine interventions, neuromodulation, minimally invasive therapies, and multidisciplinary chronic pain pathways.
NewRegional Safety Manager Aviva Staffing IncRegional Safety ManagerEaston, MA$100,000–$120,000 / yearFull timeThe Regional Safety Manager will work directly with field crews, supervisors, and operations leaders to reinforce safe work practices while keeping projects moving. These companies are part of the broader network, which provides shared resources and support, while allowing each business to operate with its own local identity and leadership.
Safety Director II Gilbane Building CoSafety Director IIBoston, MAComprehensive knowledge of construction safety principles, techniques, and methods Comprehensive knowledge of OSHA laws, regulations, and policies Capable of identifying known potential exposures and recommending corrective action Strong computer skills and familiarity with the Microsoft Office suite. • Works in real-time with Gilbane Insurance Group, Senior Management, Corporate and Division Safety Directors to identify loss leaders and effectively create safety procedures to reduce the number and severity of claims on all projects.
Safety Director II Next 150 Construction, LLCSafety Director IIBoston, Massachusetts$185,000–$245,000 / yearFull timeWorks in real time with Gilbane Insurance Group, Senior Management, Corporate and Division Safety Directors to identify loss leaders and effectively create safety procedures to reduce the number and severity of claims on all projects. • Regularly visit key projects within area of responsibility with Division Safety Directors to mentor, support development and ensure consistent application of safety program; organize minimum field presence and coaching expectations.
Director of Safety & Training Raymond Search GroupDirector of Safety & TrainingNorth Andover, MassachusettsWe are seeking an experienced Director of Safety & Training to lead instructional operations for a CDL training program focused on developing the next generation of professional drivers. This senior-level leadership role is responsible for ensuring excellence in training delivery, safety, and regulatory compliance across all phases of instruction.
Director of Safety, Security, and Emergency Management Sturdy Memorial HospitalDirector of Safety, Security, and Emergency ManagementAttleboro, MA$101,120.77–$157,957.62 / yearThe Director serves as the primary liaison with internal leaders and external partners (e.g., public safety, emergency management, and regulatory agencies) and ensures preparedness for all-hazards events through planning, training, exercises, response, recovery, and mitigation activities consistent with national incident management principles and healthcare best practices. The Director provides enterprise leadership for Safety, Security, Emergency Management, and Hazardous Materials programs to protect patients, visitors, employees, providers, and volunteers.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)Cambridge, MA$185,500–$344,500 / yearInternal Title: Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. You will be a critical enabler of portfolio progression, providing authoritative nonclinical safety leadership, regulatory credibility with Health Authorities, and strategic integration across therapeutic areas and modalities.
Director, Quality & Patient Safety Boston Medical CenterDirector, Quality & Patient SafetyBoston, MA$122,000–$177,000 / yearParticipates in DoM and QPS Department meetings including Inpatient Directors meeting, Ambulatory GIM meeting, QPS Medical Chiefs meeting, M and Ms, DOM Grand Rounds, QPC and Patient Safety Steering Committee and other meetings as requested. The Director coaches, mentors, and provides educational programs for staff and residents regarding quality improvement processes, program development to improve patient outcomes, clinical efficiency and value, patient-centered care, and patient satisfaction.
NewAssociate Director, Safety Scientist AlexionAssociate Director, Safety ScientistBoston, MassachusettsAuthoring safety sections, in collaboration with team members, on regulatory responses, IBs/CCDS, protocols, ICFs, Data Monitoring Committee reports and requests, and other documents, and provide the necessary quality control to ensure alignment with core safety position. The Associate Director, Safety Scientist plays a leadership role within Global Patient Safety (GPS) to actively evaluate and manage risk in collaboration with the GPS Medical Director(s) and cross-functional team members within the global regulatory framework.
Director, Patient Safety ICSR Vertex PharmaceuticalsDirector, Patient Safety ICSRBoston, MassachusettsRemoteThis position manages the technical aspects of end-to-end safety case intake, processing, quality control, and regulatory submissions within a therapeutic area (as assigned) covering the applicable drug, biologic, medical device, and combination products, ensuring operations are consistent, compliant, and inspection-ready worldwide. The role also represents GPS in cross-functional initiatives and requires strong technical PV expertise, communication, project management, and vendor management skills.
Associate Medical Director, Global Drug Safety Biogen IncAssociate Medical Director, Global Drug SafetyCambridge, MA$194,000–$267,000 / yearRegular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance. The Associate Medical Director, Global Safety Physician will be responsible for global pharmacovigilance for investigational and/or marketed products, including: • review and analysis of safety data • design of clinical trials • identification and investigation of safety signals • management of benefit-risk profile for assigned compounds and products.