Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver’s license information, etc) via email or messenger tools, or for a financial deposit of any kind. p>Reporting to the Head of CI & RPM, this role proactively identifies, evaluates, and shapes external opportunities across PROTACs, molecular glues, monovalent/direct degraders, degrader platforms, E3/UPS biology including CRBN, VHL, and novel E3 ligases, target engagement, proteomics/chemoproteomics, structural and computational degrader design, Degrader Antibody Conjugates (DACs), next-generation induced-proximity technologies such as RIPTAC and TCIP, and other oncology-relevant targeted-delivery or induced-proximity modalities. Responsibilities and Accountabilities:
External Ecosystem Engagement & Catalytic Scouting:
- Build trusted access to academic investigators, KOLs/KEEs, biotech founders, incubators, investors, CROs, tech-transfer offices, venture creation groups, and scientific consortia focused on TPD, induced proximity, oncology chemical biology, proteomics, and degrader-conjugate science.
This includes maintaining the healthy financial status of all accounts within the finance manager''s portfolio ensuring compliance of sponsor and institutional terms and conditions as well as proposal development, submission, and post-submission follow-up for manager''s portfolio of investigators and others as needed. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
Reporting to the Head of CI & RPM, this role proactively identifies, evaluates, and shapes external opportunities across PROTACs, molecular glues, monovalent/direct degraders, degrader platforms, E3/UPS biology including CRBN, VHL, and novel E3 ligases, target engagement, proteomics/chemoproteomics, structural and computational degrader design, Degrader Antibody Conjugates (DACs), next-generation induced-proximity technologies such as RIPTAC and TCIP, and other oncology-relevant targeted-delivery or induced-proximity modalities. + Actively track scientific and company activity across PROTACs, molecular glues, monovalent/direct degraders, novel E3 ligase recruiters, CRBN/VHL biology, target engagement, proteomics/chemoproteomics, next-generation induced-proximity technologies such as RIPTAC and TCIP, and DACs.
li>Working knowledge of areas such as: Trading workflows, Portfolio management processes, Portfolio analytics, Investment risk management, Order management and execution workflows, Investment compliance, IBOR and performance processes, Front-office data and operating models, OMS/EMS platforms and investment technology ecosystems.
This role is ideal for someone with experience at an asset manager, investment technology vendor, or service provider who wants to move beyond project delivery and operations into a role focused on research, writing, benchmarking, and market analysis.
Marlborough, MA20 days ago
Founded in 1998 and headquartered in Farmington Hills, MI, Kyyba has a global presence delivering high-quality resources and top-notch recruiting services, enabling businesses to effectively respond to organizational changes and technological advances. • Over time, and as business needs allow, cross-train in other workstreams as needed to support the team and organization growth such as filtration, formulation, Dry lab and Fab work, etc.
We pioneered cloud computing and never stopped innovating thats why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. Our team includes Account Managers, Solutions Architects, Customer Success Managers, and Higher Education and Research specialists who work together to deliver exceptional outcomes for academic institutions.
Marlborough, MA20 days ago
Today, On-Board is a thriving privately held family of companies with services including: Consulting, Professional Engineering, Industrial Maintenance and Facility Management, Contracted Manufacturing and Production Services, as well as Temporary Staffing and Recruiting throughout North America. Polymer & Organic Synthesis- Perform hands-on polymer and/or organic synthesis of monomers, oligomers, and polymers at the laboratory scale (typically 100 mL–20 L), following established procedures and safety protocols.
SUMMARY: Under the general supervision of the Director of the Sleep and Circadian Methods Research Core, together with the supervision of the COBRE Center Director, the role of the Sleep and Circadian Rhythms Methods Research Core Research Assistant (SCMRC RA) is to serve as key support for the COBRE Center for Sleep and Circadian Rhythms in Child and Adolescent Mental Health's project leaders as they integrate sleep and circadian rhythms methodologies into their projects. Brown University Health employees are expected to successfully role model the organization's values of Compassion, Accountability, Respect, and Excellence as these values guide our everyday actions with patients, customers and one another.
Department Overview: Located in Boston''s historic South End, the Department of Medicine at Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center is renowned for its impact of teaching and research programs and state-of-the-art clinical care for patients. In close partnership with the Vice Chair of Research for Clinical and Implementation Sciences, this role will ensure alignment across the full research continuum-from bench to bedside to population health-while identifying emerging scientific opportunities and driving strategic investments in faculty, infrastructure, and technology.
Providence, RI30+ days ago
The core Success Factors include: Instill Trust and Value Differences Patient and Community Focus and Collaborate In addition, our leaders will demonstrate an aptitude for: Ensure Accountability and Build Effective Teams Drive Vision and Purpose and Optimize Work Processes By applying core and leadership competencies, leaders help Brown University Health achieve its strategic goals. The position has direct responsibility for day-to-day management of all administrative and operational functional areas including research administration, compliance, reporting, laboratory operations, human resources, communications, professional development programs, volunteer programs, space and resource allocation.
li>Collaborate closely with Workshop Specialists, Research and Design Engineers, Autodesk Researchers, residents, product teams, and external partners to translate operational needs into well-scoped research experiments. This may include machine utilization, workflow planning, job scheduling, safety and training systems, documentation, predictive maintenance, quality control, fabrication intelligence, and data-informed decision-making across workshop environments.
Cambridge, MA30+ days ago
We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options. This role owns the full lifecycle of research instrumentation and partners closely with Research, Finance, Facilities, IT, Quality, and external vendors to minimize downtime, enable automation, and support scalable, reproducible science.
Cambridge, MA30+ days ago
Sound scientific and clinical judgment Familiarity with concepts of clinical research and clinical trial design, including biostatistics and regulatory agency organization guidelines and practices. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Board Certification (or equivalent) or specialist training is highly desirable; drug development experience in neurology (Huntington's Disease) would be a great advantage, but not essential 10+ years industry experience or equivalent clinical academic experience Sound scientific and clinical judgment Successful track record of leading Phase 2/3 clinical programs (preferably in Huntington's drug development), including major interactions with Health Authorities Familiarity with concepts of clinical research and clinical trial design, including biostatistics, regulatory agency organization, guidelines, and practices Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues Outstanding leadership and collaboration skills working within a matrix environment. Collaborate closely with Preclinical, Regulatory Affairs, Medical Affairs and Commercial to ensure tight strategic integration of product development plans Be accountable via Clinical Research and Operations for all relevant timelines and deliverables Drive/supervise all major written deliverables (regulatory submissions, original articles, abstracts), and presentation materials Be responsible (as appropriate in line with SOPs) for final review and sign off with respect to all controlled documents including protocols, IBs, informed consent forms Influence internal and external audiences in a high impact, highly visible fashion Qualifications MD with strong research background or MD PhD, with a track record of successful research support and peer review publications.
p>POSITION SUMMARY: The Office Based Addiction Treatment (OBAT) team in the Section of General Internal Medicine at Boston Medical Center seeks a highly motivated individual to provide administrative, operational and project support for its statewide capacity-building efforts with community healthcare providers integrating addiction treatment into office-based settings.
JOB RESPONSIBLITIES:
Project Coordination for OBAT Training and Technical Assistance (TTA):
ul>Serve as the market research lead across VPC assets supporting programs from preclinical through Phase 3. Lead insight generation to inform key decisions including indication prioritization, target product profile, positioning, and lifecycle strategy. Alnylam is seeking a Director of Market Research to support the Value Pipeline Commercialization (VPC) organization across the full pipeline from preclinical through Phase 3, spanning multiple therapeutic areas and potential business development opportunities.
The Section of Hematology and Medical Oncology at Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center is a rapidly expanding and innovative academic and clinical department that includes over 50 faculty members and over 100 staff, with a mission to provide high-level clinical care and lead research that reflects a diverse patient population. Organizes and coordinates departmental meetings or committees, including reserving conference rooms, creating power point slides, setting up room equipment and procuring food and beverage if necessary.
Providence, RI30+ days ago
p>SUMMARY: Under supervision of the Director/Research Center Manager of the Center for Behavioral and Preventive Medicine (CBPM), the Research Program Manager provides administrative leadership and operational oversight for the Stress Trauma and Resilience (STAR) COBRE Program, the Stress, Trauma, and Resilience (STAR) T32 Program, the CBPM Training and Mentorship Programs, and general CBPM Program Management. The core Success Factors include: Instill Trust and Value Differences Patient and Community Focus and Collaborate In addition, our leaders will demonstrate an aptitude for: Ensure Accountability and Build Effective Teams Drive Vision and Purpose and Optimize Work Processes By applying core and leadership competencies, leaders help Brown University Health achieve its strategic goals.
Reporting to the Clinical Research Program Manager (or local Hospital Administrator/Clinic Director) and Research Programs Office at SHC International Headquarters, the CRC provides support in accordance with SHC's policies and procedures, SHC's hospital regulations, the Code of Federal Regulation, and Good Clinical Practice guidelines, when applicable. experience with site management, study management, IRBs, and federal regulations regarding clinical research compliance requiredExperience in the coordination of intergroup or multi-site clinical studies preferred.
strong>Key Responsibilities- Lead the day-to-day operations, supervision, and development of the Clinical Research team, ensuring staff have the training, resources, and support needed to successfully recruit participants and execute study activities across a portfolio of research studies.
- Provide ongoing performance management, coaching, and guidance to clinical research staff while ensuring adherence to study protocols, institutional policies, and regulatory requirements; collaborate closely with Principal Investigators to address study needs and priorities.
Cambridge, MA30+ days ago
This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding CVM portfolio, which spans a number of disease areas including kidney disease. Medical Director, Clinical Research is expected to play a leading and influencing role in the overall clinical development strategies for the programs and to drive progress and operational excellence for the associated clinical trials.
This is an opportunity to provide clinical leadership in developing RNAi therapeutics in client's rapidly expanding portfolio, which spans the areas of rare genetic diseases, cardio-metabolic diseases, neuroscience, hematology and hepatology. The Senior Director, Clinical Research, will work in a matrix organization across Regulatory, Biostatistics, Clinical Operations, Preclinical, Commercial & QA teams to ensure fully harmonized and integrated development strategies.
Cambridge, MA30+ days ago
This is an opportunity to provide clinical leadership in developing RNAi therapeutics in client's rapidly expanding portfolio, which spans the areas of rare genetic diseases, cardio-metabolic diseases, neuroscience, hematology and hepatology. The Senior Director, Clinical Research, will work in a matrix organization across Regulatory, Biostatistics, Clinical Operations, Preclinical, Commercial & QA teams to ensure fully harmonized and integrated development strategies.
Cambridge, MA30+ days ago
This is an opportunity to provide clinical leadership in developing RNAi therapeutics, rapidly expanding portfolio, which spans the areas of rare genetic diseases, cardio-metabolic diseases, neuroscience, hematology and hepatology. While the primary focus responsibility will be as clinical lead physician on client's autoimmune liver disease programs, the role may support across a range of therapeutic areas and all stages of development may be required as pipeline assets evolve.
RequiredB.S. or Associate degree in a technical or scientific field related to chemistry, chemical engineering, material science, biological science, with industrial lab experience with clean room + wafer level processing methods & tools. Demonstrate ability to work well on cross-functional and global teams with personnel at multiple levels, including Asia-based customers and commercial points of contact.
p>Core Competencies: • Deep understanding of wealth management ecosystems, advisor business models, and industry trends • Strong analytical, critical thinking, and problem-solving skills • Ability to synthesize large amounts of information into clear, concise findings • Strong communication and presentation skills • Ability to influence stakeholders and work cross-functionally in a dynamic environment. The firm provides a wide range of advisor affiliation models, investment solutions, fintech tools and practice management services, ensuring that advisors and institutions have the flexibility to choose the business model, services, and technology resources they need to run thriving businesses.
Boston, Massachusetts30+ days ago
ul>Lead the transformation of insights and analytics by anticipating industry and competitive signals, setting a clear vision aligned to enterprise priorities, and modernizing traditional data approaches (including GenAI), while identifying, piloting, and scaling innovative analytics and emerging technologies in close partnership with enterprise leaders and Global Capabilities Centers—to enable foresight driven strategy, decision making, and immediate business impact.
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.
Cambridge, MA30+ days ago
p>Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. This individual will play a key role in shaping how our science is executed-designing the systems, workflows, and external collaborations that enable scientists to focus on innovation while accelerating the generation of high-quality data and platform insights.
Cambridge, MA30+ days ago
The role will work closely with senior scientific leaders and subject matter experts across research disciplines (including chemistry/computational sciences and biology) and collaborate broadly with Medical, Development, IR, and Commercial colleagues to ensure external insights are rapidly translated into strategic and portfolio implications. The position will stay on top of the rapidly evolving landscape (peer reviewed publications, press releases, patents, and congress readouts) and develop independent, data-driven insights in close collaboration with internal or external subject matter experts.
Cambridge, MA30+ days ago
p>This career opportunity will allow you to lead the team responsible for addressing critical pharmacology questions emerging from clinical studies, using in vitro and disease-relevant preclinical models to interrogate antigen-specific T cell dynamics, immune activation pathways, tumor-immune interactions, and mechanisms of response and resistance. Design and oversee rigorous in vitro and disease-relevant preclinical studies to interrogate antigen-specific T cell responses, immune activation pathways, tumor-immune interactions, mechanisms of response and resistance, and scientific rationale for combination strategies.
Cambridge, Massachusetts30+ days ago
The role will work closely with senior scientific leaders and subject matter experts across research disciplines (including chemistry/computational sciences and biology) and collaborate broadly with Medical, Development, IR, and Commercial colleagues to ensure external insights are rapidly translated into strategic and portfolio implications. The position will stay on top of the rapidly evolving landscape (peer reviewed publications, press releases, patents, and congress readouts) and develop independent, data‑driven insights in close collaboration with internal or external subject matter experts.
p/>Please be advised that Fidelity’s business is governed by the provisions of the Securities Exchange Act of 1934, the Investment Advisers Act of 1940, the Investment Company Act of 1940, ERISA, numerous state laws governing securities, investment and retirement-related financial activities and the rules and regulations of numerous self-regulatory organizations, including FINRA, among others. These benefits include comprehensive health care coverage and emotional well-being support, market-leading retirement, generous paid time off and parental leave, charitable giving employee match program, and educational assistance including student loan repayment, tuition reimbursement, and learning resources to develop your career.
Cambridge, Massachusetts30+ days ago
The role will work closely with senior scientific leaders and subject matter experts across research disciplines (including chemistry/computational sciences and biology) and collaborate broadly with Medical, Development, IR, and Commercial colleagues to ensure external insights are rapidly translated into strategic and portfolio implications. The position will stay on top of the rapidly evolving landscape (peer reviewed publications, press releases, patents, and congress readouts) and develop independent, data‑driven insights in close collaboration with internal or external subject matter experts.
p>As project lead, the G-TRL builds a connected view of the project within the Neuroscience TA strategy and treatment paradigm and can represent all core expertise at depth and align with stakeholders and sponsors across the organization including Research, Clinical Development and Commercial stakeholders and executive level governance committees. Leveraging a proven track record of leading at least 3 discovery programs to clinic, The Global Therapeutic Research Lead (G-TRL) is a pipeline critical strategic leader responsible for driving Research projects to the clinic.
Cambridge, Massachusetts19 days ago
Learn more about Flagship at www.flagshippioneering.com. By combining a large and growing proprietary in vivo biodistribution dataset, machine learning-guided lipid nanoparticle optimization, modular targeted particle design, and integrated translation and manufacturing capabilities, Mirai helps partners accelerate development, reduce technical risk, and pursue high-value programs making delivery a strategic advantage.
Boston, Massachusetts30+ days ago
p style="text-align:inherit"/>At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Understanding of key analytical deliverables for late-stage programs including method development, validation, specification setting, stability, release testing and analytical strategies to bring these individual items together collectively for a fast-paced program.
Cambridge, MA30+ days ago
li>Thorough understanding of relevant in vivo mammalian disease models strongly preferred, with experience in intracerebroventricular (ICV) injections, necropsy, behavioral analysis, ex vivo tissue processing, and downstream analysis including molecular and histological assessments. Working closely with a multidisciplinary team, the Scientist will be responsible for identifying and validating novel drug targets, championing early programs, and supporting programs as they advance through clinical stages.
Cambridge, MA30+ days ago
p>Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers. The Research Department at Alnylam is seeking a Principal Scientist to join a growing team responsible for advancing RNAi therapeutics into the future, by opening up targeted delivery to all tissues.
General Summary: Reporting to the SVP of Research and Site Head of Boston and Seattle Research, the Chief of Staff (Project Management & Strategic Operations Director) is a leadership role that sits on the Boston and Seattle Research Leadership Teams and champions functional and cross-functional project management excellence across Vertex. Leads development of clear, compelling executive communications, including presentations and briefing materials for Executive Committee members, select external audiences, and internal scientific and non-scientific audiences, ensuring complex scientific and strategic information is synthesized into decision‑ready insights.
Marlborough, MA5 days ago
strong>Analytical Characterization- Operate and maintain key analytical instruments such as GPC, HPLC, UPLC, NMR and related chromatography tools; perform routine calibrations and basic troubleshooting. Polymer & Organic Synthesis
- Perform hands-on polymer and/or organic synthesis of monomers, oligomers, and polymers at lab scale (typically 100 mL–20 L), following established procedures and safety protocols.
Marlborough, MA20 days ago
strong>Analytical Characterization- Operate and maintain key analytical instruments such as GPC, HPLC, UPLC, NMR and related chromatography tools; perform routine calibrations and basic troubleshooting. Polymer & Organic Synthesis
- Perform hands-on polymer and/or organic synthesis of monomers, oligomers, and polymers at lab scale (typically 100 mL–20 L), following established procedures and safety protocols.
Primary Responsibilities: Informing development strategies from HEOR / market access perspective Represent the HEOR and market access perspective in internal clinical development and regulatory forums Provide critical input into clinical development plans, including protocol design, endpoint selection, and other aspects of clinical trial evidence generation, to ensure alignment with future payer and HTA expectations Communication of value to payers and HTA bodies Lead development of AMCP dossiers for US payers Lead development of cost-effectiveness models for NICE and other HTA bodies requiring formal cost-effectiveness analyses Serve as a core team member for HTA submissions outside the US, with responsibility for shaping and stress-testing value narratives included in pricing and reimbursement dossiers and interpreting and recommending evidence to support such narratives, in a way that optimizes both credibility and relevance for payer decision-making Make substantial contributions to other payer communication materials (e.g., Medical Value Liaison slide decks) and launch readiness activities as needed Leading real-world evidence strategy and execution of real-world analyses Lead planning of real-world evidence generation activities to address evidence gaps as needed for informing decision-making by payers, HTA bodies, and clinicians Oversee execution of real-world data analyses, ensuring analytical rigor and fitness for purpose Interpret and translate results from real-world analyses into peer-reviewed publications and other external communications intended to meaningfully inform clinical practice and payer/HTA decision-making. Accordingly, the Director, Global HEOR, helps shape development plans, evidence strategies, and value narratives so that they align with how payers and health technology assessment (HTA) bodies make decisions, balancing analytical rigor with a clear focus on what is relevant for decision-making.
Acquired by Harris Healthcare in 2017, the company provides a comprehensive suite of services, including Practice Management, Medical Billing, Population Health, and Patient Engagement tools, all designed to enhance clinical efficiency and patient care. As a wholly owned subsidiary of Constellation Software Inc. ("CSI", symbol CSU on the TSX), Harris has become the cornerstone for CSI's investment in utility, local government, school districts, public safety, and healthcare software verticals.