Senior Scientist I/II - Oncology/Immuno-Oncology

Job ID

REQ-10091289

Nov 03, 2026

USA

Summary

Role Type: Onsite Working #LI-OnsiteLocation: Cambridge, Massachusetts, United StatesRelocation: Relocation assistance is available for this position Join Novartis Oncology-OIT (Oncology Immune Therapies) group for an exciting opportunity to make a significant impact on cancer immunology.As a key member of our dynamic, multidisciplinary team, you will contribute to the development of groundbreaking therapeutic modalities.Your work will play a crucial role in advancing new therapies and bringing our innovative drugs to patients.

About the Role

Key Responsibilities:Support drug screening, novel target identification and validation, including working with replication-incompetent lentiviruses, mRNA-LNP, cell lines, primary cells, and tissuesDevelop and perform cell-based assays, flow cytometry, and biochemistry-based assays for drug discovery. Occasionally, you will also employ molecular biology (e.g. gel electrophoresis, cloning, qPCR, western blot, etc.) Conduct biological and pharmacological studies by developing and performing analyses of preclinical tissue samples provided by the in vivo teamEmploy good laboratory practices, data recording, analysis and documentationCollaborate effectively while working in a matrixed environmentPresent results in lab and department meetingsAssist in writing research documents and publicationsEssential Requirements:Bachelor's degree in immunology, immuno-oncology, oncology, molecular or cell biology, or a related field is required. A master's degree is preferred.5+ years of relevant laboratory experience in industryKnowledge of immunology and expertise in cancer biology and/or immunology are requiredExpertise in tumor immunology, especially T cell mediated anti-tumor activity is highly desiredProficiency in cell culture including cell lines and primary cells, and multi-color flow cytometry is required.Extensive hands-on experience with immune cell-based assays, including primary immune cell isolation, manipulation, phenotyping, and in vitro functional assays, as well as mammalian cell line culture is highly desired.Experience with molecular cloning, qPCR, reporter assays, ELISA, viral production and transduction, mRNA-LNP-mediated gene expression in primary cells, gene silencing (RNAi or CRISPR), or other target validation methods is a plus.Demonstrated ability to quickly learn and perform in new areas, implement new techniques and instrumentationStrong scientific motivation and rigor, with experience independently designing, developing, executing, and troubleshooting cell-based assays for drug discovery, are preferred.Excellent presentation, written and verbal communication, and interpersonal skills, with the ability to thrive in a fast-paced, collaborative environment.A record of accomplishments with peer-reviewed publications a plusWhat We OfferThis is a dual level posting and as such the salary for this position is expected to range between:Senior Scientist I: $93,800 - $174,200 per yearSenior Scientist II: $98,700 - $183,400 per yearThe final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-cultureBenefits and Rewards: Learn about all the ways we'll help you thrive personally and professionally.Read our handbook (PDF 30 MB)

EEO Statement:The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.Accessibility & Reasonable AccommodationsThe Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Division

Biomedical Research

Business Unit

Research

Location

USA

State

Massachusetts

Site

Cambridge (USA)

Company / Legal Entity

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Research & Development Biomedical Research USA

Job ID

REQ-10091289

Senior Scientist I/II - Oncology/Immuno-Oncology

Apply to Job

Job ID

REQ-10091289

Senior Scientist I/II - Oncology/Immuno-Oncology

Apply to Job