We are sharing a specialised part-time consulting opportunity for experienced preclinical R&D scientists with hands-on expertise in antibody-drug conjugates (ADCs), bispecific or multispecific antibodies, and in-house drug development.
This role supports a research initiative focused on improving how advanced computational systems reason about real-world biologics discovery and preclinical development. Selected experts will review scientific materials and programme data, evaluate technical outputs, contribute practical judgement on modality and development decisions, and help define high-quality data structures grounded in authentic ADC and bispecific R&D workflows.
Key Responsibilities
ADC & Bispecific Programme Review
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Review technical materials and scientific data from ADC, bispecific, and multispecific antibody programmes
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Evaluate whether analyses and conclusions reflect realistic preclinical development practice
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Identify weak assumptions, unsupported claims, and biologically implausible outputs
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Apply hands-on programme experience to complex development scenarios
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Assess trade-offs involving efficacy, safety, developability, manufacturability, and programme risk
Target & Modality Strategy
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Evaluate target-selection and modality-selection decisions
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Assess biological rationale, therapeutic hypothesis, and competitive differentiation
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Review trade-offs between ADC, bispecific, multispecific, and other biologic approaches
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Identify risks associated with target biology, expression patterns, mechanism of action, or therapeutic window
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Apply practical judgement to programme progression and prioritisation decisions
ADC Development
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Contribute expertise across antibody selection, linker strategy, payload choice, conjugation, and overall ADC design
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Evaluate potency, selectivity, internalisation, stability, exposure, and toxicity considerations
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Review development decisions affecting efficacy and therapeutic index
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Assess preclinical evidence supporting candidate progression
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Identify common failure modes and optimisation challenges in ADC programmes
Bispecific & Multispecific Antibodies
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Review programmes involving bispecific or multispecific antibody architectures
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Evaluate target combinations, binding strategy, format selection, and functional activity
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Assess developability, PK/PD, immunogenicity, safety, and manufacturability considerations
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Review translational evidence and candidate-selection decisions
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Identify modality-specific risks that may affect progression toward the clinic
Preclinical & Translational Development
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Apply experience across in vitro, in vivo, translational, pharmacology, and PK/PD workflows
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Evaluate experimental design and interpretation of preclinical evidence
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Assess how findings influence candidate optimisation and development strategy
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Review programme readiness for lead optimisation or IND-enabling development
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Identify evidence gaps, unresolved risks, and appropriate next-stage studies
Cross-Functional R&D Expertise
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Contribute expertise from areas such as:
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Discovery biology
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Medicinal chemistry
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Protein and antibody engineering
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Computational drug discovery
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In vivo and translational research
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Pharmacology and PK/PD
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Toxicology
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CMC and formulation
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Apply cross-functional judgement to integrated programme decisions
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Evaluate how findings from different disciplines affect candidate selection and development
Scientific Data Evaluation
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Label, classify, and annotate scientific data and technical outputs
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Identify meaningful experimental signals, development decisions, and failure modes
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Evaluate the relevance and quality of information used in downstream research workflows
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Help establish consistent standards for scientific review and annotation
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Translate practical R&D expertise into structured, usable data
Dataset & Research Development
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Help define structure and quality standards for scientific data pipelines
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Identify which experimental and development variables should be captured
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Surface workflow details that are often missed outside hands-on preclinical R&D
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Participate in expert discussions, interviews, and research engagements
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Provide practical perspective on how biologics programmes are advanced in industry
Ideal Profile
- 5+ years of relevant pharmaceutical or biotechnology R&D experience, with flexibility for candidates demonstrating exceptional technical depth
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Hands-on, non-administrative preclinical R&D experience within a company developing its own therapeutic assets
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Direct professional experience with ADCs and/or bispecific or multispecific antibodies
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Experience at an organisation that has advanced internal drug programmes toward or into clinical development
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Current or recent work in a core R&D function such as discovery biology, medicinal chemistry, protein or antibody engineering, computational discovery, translational science, pharmacology, PK/PD, toxicology, or CMC
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Strong understanding of biologics discovery, optimisation, and preclinical development
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Experience advancing a programme through lead optimisation, IND-enabling studies, or preclinical development is highly valued
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Experience within mid-sized, emerging, or resource-constrained biotechnology environments is advantageous
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Seniority may range from experienced individual contributor through Director level
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Strong scientific judgement and ability to explain development decisions clearly
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This opportunity is best suited to hands-on drug-development professionals rather than backgrounds focused primarily on CRO/CDMO services, academic-only research, QC/analytical functions, clinical development, diagnostics, regulatory affairs, or medical writing
Engagement Details
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Part-time independent contractor engagement
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Fully remote
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Expected commitment of approximately 10 hours per week
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Ongoing engagement based on project needs
- Compensation: $50–$90/hour
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Contributors will interact directly with the assigned research team
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Projects may be extended, shortened, or concluded based on project needs and performance
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Work must be completed without using confidential or proprietary information belonging to any employer, client, institution, or other third party
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H1-B and STEM OPT support is unavailable for this engagement
About the Platform
This opportunity is available through 24-MAG LLC. We connect experienced professionals with remote consulting opportunities across technical, evaluation, and project-based workstreams.
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