Postdoctoral Fellow-MSH-30025-251

Mount Sinai Health System

New York, NY

JOB DETAILS
SALARY
$72,500–$80,000 Per Year
SKILLS
Artificial Intelligence (AI), Cancer, Career Development, Cataloguing, Cell Biology, Cell Cultures, Community Health, Community Support, Funding, Genetics, Genomics, Geriatrics, Grant Writing, Healthcare, Hospital, Informatics, Medicine, Memory Hardware, Mentoring, Molecular Biology, National Institutes of Health (NIH), News Reporting, Nursing, Ophthalmology, Outpatient Care, Patient Care, Pediatrics, Process Improvement, Publications, Stem Cells, Team Player, Technical Support, Training/Teaching, Windows PowerShell
LOCATION
New York, NY
POSTED
5 days ago

Description

Research Focus

Our research aims to uncover the molecular mechanisms that govern cancer cell behavior by focusing on:

  • Functional heterogeneity within tumors
  • Phenotypic plasticity during tumor evolution and therapy response
  • Cellular competence in tumor initiation, adaptation, and drug resistance

Rather than simply cataloging cellular states, we seek to identify the mechanisms that establish, maintain, and

regulate them. We combine genetic barcoding-based lineage tracing, functional genomics, organoid and

mouse models, CRISPR perturbations, and single-cell multiomics to track cancer evolution at clonal resolution

and uncover causal regulators of cancer cell identity and behavior.

The laboratory includes both experimental and computational researchers, fostering a collaborative and

interdisciplinary approach to studying cancer evolution and cell-state dynamics.

Current Research Areas

  • Cellular competence and tumor evolution
  • Phenotypic plasticity, memory, and adaptation
  • Developmental programs and cancer cell states

Responsibilities

Responsibilities

  • Design and execute independent research projects.
  • Perform experiments using organoid, cell culture, and mouse models.
  • Conduct genetic barcoding, lineage tracing, and functional genomics studies.
  • Contribute to manuscripts, grant applications, and mentoring activities.

Qualifications

Qualifications

Required

  • Ph.D. in Cancer Biology, Molecular Biology, Genetics, Epigenetics, Stem Cell Biology, or a related field.
  • Strong publication record or evidence of research productivity.
  • Ability to work independently and collaboratively.
  • Experience with molecular biology and mammalian cell culture.

Preferred

Experience in one or more of the following:

  • Organoids or mouse models
  • Genetic barcoding, clonal tracking, and lineage tracing
  • Single-cell genomics and multiomics
  • ATAC-seq, RNA-seq, CUT&Tag, or CUT&RUN
  • CRISPR technologies

What We Offer

Join an NIH-funded laboratory and help shape an ambitious research program at the intersection of cancer

biology, epigenetics, stem cell biology, and genomics. Trainees will receive close mentorship, access to stateof-

the-art technologies, and strong support for career development and scientific independence.

Application Instructions

Please submit: Cover letter, CV and contact information for three references to slim.mzoughi@mssm.edu

Subject line: "Postdoctoral Fellow / Assistant Scientist Application - Mzoughi Lab"

Shortlisted candidates will be contacted for an interview.

Mount Sinai is an equal opportunity employer, and we encourage applications from individuals of all

backgrounds. We value diversity and inclusion in our research community.

Employer Description

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

About the Company

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Mount Sinai Health System