Part-Time Research Technician

Indiana University Foundation

  • Indianapolis, IN
  • 2 days ago
  • $20–$22.75 Per Hour

Highlights

Perform peptide conjugation reactions, including: Maleimide-thiol coupling, Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) click chemistry, PEGylation, and Cross-linking reactions. Characterize synthesized peptides by Liquid Chromatography-Mass Spectrometry (LC-MS), Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS), and analytical HPLC.

Numbers & Facts

LocationIndianapolis, IN
Salary$20–$22.75 Per Hour

Description

Department

CANCER CENTER (IN-CANC-IUINA)

Department Information

The Indiana University (IU) Melvin and Bren Simon Comprehensive Cancer Center (IUSCCC) is the central hub for cancer research and education across Indiana University. It is the states only National Cancer Institute (NCI) designated Comprehensive Cancer Center and 1 of only 57 in the nation. The comprehensive designation recognizes the centers excellence in basic, clinical, and population research; outstanding educational activities; and effective community outreach across the state.

Job Summary

  • Perform solid-phase peptide synthesis (SPPS) using fluorenylmethyloxycarbonyl (Fmoc) chemistry.
  • Conduct peptide cleavage, deprotection, precipitation, and lyophilization.
  • Purify peptides using preparative and analytical High-Performance Liquid Chromatography (HPLC).
  • Characterize synthesized peptides by Liquid Chromatography-Mass Spectrometry (LC-MS), Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS), and analytical HPLC.
  • Perform peptide conjugation reactions, including: Maleimide-thiol coupling, Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) click chemistry, PEGylation, and Cross-linking reactions.
  • Prepare multivalent peptide vaccine constructs.
  • Optimize reaction conditions to improve purity and yield.
  • Maintain detailed laboratory notebooks and electronic records.
  • Prepare buffers, solvents, reagents, and stock solutions.
  • Manage peptide inventories, chemical stocks, and laboratory supplies.
  • Assist with technology transfer and preparation of protocols for scale-up.
  • Follow laboratory safety procedures and institutional chemical hygiene guidelines.
  • Contribute to preparation of manuscripts, grant applications, and patent documentation when appropriate.
  • Perform a wide variety of complex experiments and reports results.
  • Keep organized analytical data of performed experiments.
  • Provide support for equipment maintenance as needed.
  • Act as a liaison to students and laboratory personnel for training.
  • Maintain laboratory supply requisition and management.
  • May train junior-level staff.
  • May help plan experiments or short-term goals.

Qualifications

EDUCATION

Required

  • Bachelors degree (preferably in science, chemistry, or a related field).

SKILLS

Required

  • Proficient communication skills

Working Conditions / Demands

The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The person in this role must be able to perform the essential functions with or without an accommodation.

Work Location

Medical Research and Library Building

975 West Walnut Street, Suite 537

Indianapolis, Indiana 46202

Advertised Salary

$20.00 - 22.75 per hour

Job Classification

Career Level: Part Time Employee

FLSA: Nonexempt

Job Function: Part Time Employee

Job Family: Part Time Employee

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Posting Disclaimer

This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.

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Equal Employment Opportunity

Indiana University is an equal opportunity employer and provider of ADA services and prohibits discrimination in hiring. See Indiana University Notice of Non-Discrimination here which includes contact information.

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