| Location | Palo Alto, California |
| Website | \"https://guardanthealth.com/contact/privacy-notice-for-job-applicants/\" |
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Associate Director, Oncology Product Management (Therapy Selection)
The Guardant Health Associate Director, Oncology Product Management (Therapy Selection) reports to the Senior Director of Product Management and helps drive market evolution across Guardant Health's liquid biopsy therapy selection portfolio.
This is a high-impact role for an execution-driven product leader who thrives at the intersection of product innovation, clinical impact, and commercial growth.
In this role, you will own roadmap execution and commercial readiness for the Guardant360 Liquid therapy selection products, and contributes to the product strategy that shapes how these diagnostics enter and expand within standard of care.
The Associate Director, Oncology Product Management requires a strong clinical science foundation alongside product management judgment.
Responsibilities
Own and drive end-to-end execution of the Guardant360 Liquid and Guardant360 Liquid CDx roadmaps — new biomarkers and features, assay optimization, workflow enhancements, and indication/companion-diagnostic label expansion.
Translate portfolio strategy into a prioritized, resourced roadmap and contribute to the multi-year product strategy.
Own product requirements and prioritization for the product line, making day-to-day trade-off decisions within the roadmap.
Lead cross-functional programs across product, engineering, bioinformatics, and operations; drive phase gates and release-readiness reviews for major launches.
Own product lifecycle and change management activities across both the LDT and CDx offerings.
Partner with R&D, clinical development, regulatory, and quality to advance CDx submissions and ensure compliance in regulated environments (IVD, CLIA, CAP, FDA).
Partner with biopharma stakeholders to align companion diagnostic development with drug programs and biomarker-driven trials.
Own competitive and landscape analysis for the product line and contribute to Guardant's differentiation strategy.
Provide clinical and technical leadership for the therapy selection portfolio, translating evolving molecular oncology, biomarker, and treatment evidence into product priorities, roadmap recommendations, and cross-functional decisions
Partner with Market Access and Medical Affairs on evidence and reimbursement strategy, and contribute to scientific communications and publications.
Lead, coach, and develop direct reports by setting clear goals, providing timely feedback, supporting career growth, and fostering a high-performance, accountable team culture.
Manage core people leadership responsibilities, including performance management, prioritization, capacity planning, hiring support, and ensuring team members are aligned to business priorities and execution expectations.
Required Qualifications
Typically requires: ~12 yrs with a Bachelor's; 8 with a Master's; 5 with a PhD; or 3 with a PharmD/MD within life sciences, bioengineering, molecular biology, or a related field.
Experience in product management, clinical science, medical affairs, or strategy within diagnostics or oncology.
Strong clinical science grounding and knowledge of clinical practice in oncology and biomarker-driven therapy selection.
Deep understanding of liquid biopsy and molecular diagnostics, including familiarity with NGS assays.
Working knowledge of diagnostic assay workflows and regulated-lab environments (CLIA, CAP, IVD, FDA).
Strong strategic thinking, execution rigor, and cross-functional collaboration.
Advanced degree (MBA, MPH, PhD, PharmD, or MD).
Familiarity with companion diagnostic (CDx) development and regulatory submissions.
Experience with Guardant360 or comparable liquid biopsy products.
Prior biopharma engagement and knowledge of the competitive and reimbursement landscape.
Required people management experience, including direct oversight of team members, goal setting, performance feedback, coaching, development planning, and accountability for team execution.
AI & Digital Fluency
Hybrid Work Model:This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $204,700 - $281,500 Other US Location(s) Base Pay Range: $173,995 - $239,275 If the role is performed in Colorado, the pay range for this job is: $184,230 - $253,350
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to
Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at: http://www.guardanthealth.com/jobs/