Associate Director, Clinical Pharmacology City TherapeuticsAssociate Director, Clinical PharmacologyCambridge, Massachusetts$174,000–$196,000 / yearThe successful candidate will work in a highly cross-functional environment, partnering closely with Clinical Development, Regulatory Affairs, Clinical Operations, Biostatistics, Data Science, CMC and external collaborators to drive data-driven decision making and advance clinical development. Lead and execute model-informed drug development (MIDD) activities, including population PK, exposure-response, PBPK, and mechanistic PK/PD modeling, either independently or in collaboration with quantitative scientists, to support regulatory interactions and development planning.
Associate Director, Toxicology (Nonclinical Safety Evaluation) City TherapeuticsAssociate Director, Toxicology (Nonclinical Safety Evaluation)Cambridge, Massachusetts$174,000–$196,000 / yearThe Ideal Candidate • PhD or DVM, or equivalent advanced degree in Toxicology, Pharmacology, Pathology, Veterinary Sciences, or a related field, with 5+ years, Masters with 7+ or a Bachelors with 10+ of relevant experience in biotech or pharmaceutical drug development, or direct experience as a Study Director at a GLP-qualified CRO.• Strong experience overseeing outsourced nonclinical safety studies and critically reviewing protocols, data, and final reports.• The Role We’re seeking an Associate Director, Nonclinical Safety Evaluation (NSE) who will play a pivotal role in overseeing and critically evaluating nonclinical safety studies across City’s RNAi therapeutic programs.
Senior Director, Executive Compensation ModernaTXSenior Director, Executive CompensationCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Lead the preparation and review of executive compensation disclosures for the annual proxy statement, including drafting and coordinating the Compensation Discussion & Analysis (CD&A), compensation tables, supporting narratives, and related SEC filings in partnership with Legal, Finance, and external advisors.
Director, Data Management Operational Excellence ModernaTXDirector, Data Management Operational ExcellenceCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. As a senior leader within Data Management, the Director translates portfolio strategy into operational execution frameworks, proactively mitigates regulatory and operational risk, and ensures sustainable inspection readiness through robust oversight, metrics, and process harmonization.
Associate Director, Marketing - Oncology ModernaTXAssociate Director, Marketing - OncologyCambridge, MassachusettsThis role plays a key role in developing and scaling commercial capabilities, operational processes, and launch readiness activities to support successful oncology product launches and sustained growth This role sits at the intersection of commercial strategy, field execution, and operational excellence, ensuring that the organization is equipped with best-in-class tools, processes, and capabilities to compete in a complex and rapidly evolving market. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Associate Director, Sterility Assurance ModernaTXAssociate Director, Sterility AssuranceNorwood, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Lead or support investigations with potential impact to sterility assurance (e.g., EM excursions, media fill failures, decontamination issues, bioburden or sterility failures), ensuring robust root cause analysis and effective corrective and preventive actions.
Programs Underwriting Director ProSelect Insurance CompanyPrograms Underwriting DirectorBoston, MassachusettsOperating within our carrier's Delegated Underwriting Program team, this role operates as the carrier-side owner of the program business, directly aligned with segment objectives and responsible for disciplined execution across the portfolio. Must be knowledgeable in insurance policy contracts, medical malpractice liability, general liability, directors’ and officers’ liability, managed care liability, excess/umbrella liability, reinsurance and SIR and deductible programs.
Associate Director, Compensation ModernaTXAssociate Director, CompensationCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This role partners closely with HR Business Partners, Talent Acquisition, Finance, Legal, and business leaders to ensure compensation programs are competitive, equitable, scalable, and aligned with market practices and organizational objectives.
Tax Director - Global Information Reporting PricewaterhouseCoopers LLPTax Director - Global Information ReportingBoston, MA$150,000–$438,000 / yearPwC does not intend to hire experienced or entry level job seekers who will need, now or in the future, PwC sponsorship through the H-1B lottery, except as set forth within the following policy: https://pwc.to/H-1B-Lottery-Policy . At PwC, we recognize that conviction records may have a direct, adverse, and negative relationship to responsibilities such as accessing sensitive company or customer information, handling proprietary assets, or collaborating closely with team members.
Director, Resilience Lifecycle & Supply Chain Operations ModernaTXDirector, Resilience Lifecycle & Supply Chain OperationsNorwood, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. The role connects global portfolio and supply strategies with country execution, ensuring launches and lifecycle changes are delivered in a coordinated, compliant and supply-ready manner while maintaining reliable day-to-day performance.
Director, Brand & Communications Boston Dynamics, inc.Director, Brand & CommunicationsWaltham, MA$193,000–$205,000 / yearYou will lead and scale internal teams and external partners to ensure our brand narrative and top-level company messaging are consistent and impactful across earned and social media, sponsored content, shareholder and partner collaborations, and executive speaking engagements. Identify strategic executive speaking opportunities and support appearances with thought leadership narratives and content, and train new spokespeople as needed.
Business Development Director - Custom Silicon FlexBusiness Development Director - Custom SiliconLittleton, MA$164,300–$225,900 / yearThis role leads the identification, development, and closing of strategic opportunities for JetCool's liquid cooling solutions, particularly with leading semiconductor companies, advanced packaging specialists, and organizations developing high‑performance and next‑generation compute architectures. The Business Development Director- Custom Silicon, based in Littleton, MA, Austin, TX, or San Jose, CA, is a seasoned professional responsible for building long‑term, trusted‑advisor relationships with key chipmakers and emerging custom silicon innovators.
Payer Quality Consultant, Director PricewaterhouseCoopers LLPPayer Quality Consultant, DirectorBoston, MA$155,000–$410,000 / yearPreference for at least one of the following fields of study: Accounting, Actuarial Science, Analytics/Data Science, Business Administration/Management, Computer Science/Information Systems, Economics, Engineering, Finance, Government/Public Policy, Health Administration/Public Health, Mathematics/Statistics, Operations/Supply Chain, Organizational Management/Behavior, Risk Management/Insurance. PwC does not intend to hire experienced or entry level job seekers who will need, now or in the future, PwC sponsorship through the H-1B lottery, except as set forth within the following policy: https://pwc.to/H-1B-Lottery-Policy .
SAP BRIM Consultant, Director PricewaterhouseCoopers LLPSAP BRIM Consultant, DirectorBoston, MA$155,000–$410,000 / yearAs a SAP BRIM Consultant, Director, you will play a pivotal role in helping clients optimize their operational efficiency through specialized consulting services for SAP Customer Relationship Management (CRM) applications. PwC does not intend to hire experienced or entry level job seekers who will need, now or in the future, PwC sponsorship through the H-1B lottery, except as set forth within the following policy: https://pwc.to/H-1B-Lottery-Policy .
Director, Agentic Software Development CSL Behring LLCDirector, Agentic Software DevelopmentWaltham, MA$228,000–$270,000 / yearWe use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas.
Associate Director, Clinical Data Enablement 3316 Takeda Development Center AmericasAssociate Director, Clinical Data EnablementMassachusettsBS/BA (or equivalent) plus 7+ years in data ingestion/integration, ETL/ELT operations, or clinical data pipeline support, ideally supporting clinical data review and recurring study/vendor transfers. Detail-oriented, highly organized, Strong collaboration and communication; organized, self-directed, proactive problem-solver and able to manage recurring operational workloads while driving issues to closure and preventing recurrence.
Associate Director, CRM Field Operations Vertex Pharmaceuticals IncAssociate Director, CRM Field OperationsBoston, MA$164,400–$246,600 / yearProactively identifies and communicates potential new improvements to platforms, leverages subject matter expertise to support both Sales & Marketing in identifying opportunities for improvement and communicating complex technical solutions to business problems. The North America Commercial Operations CRM Field Operations Team is looking for an Associate Director, CRM Field Operations to ensure continued customer centricity and success.
Field Analytics & Reporting Associate Director, Kidney Vertex Pharmaceuticals, IncField Analytics & Reporting Associate Director, KidneyBoston, MA$157,800–$236,600 / yearDemonstrated experience in understanding, facilitating, and communicating with field sales teams and field sales leadership to drive high field adoption and field performance in understanding and utilizing operational functions, identifying areas for improvement, and measuring field impact. This role will support strategy, design, roadmap planning, delivery, and adoption of all analytics across all field roles within the Strategic Customer Engagement Team including Field Account Managers, Regional/Area Managers, Strategic Account Leads, and Virtual Field Representatives.
Senior Director, Commercialization Technology Architect Vertex PharmaceuticalsSenior Director, Commercialization Technology ArchitectBoston, Massachusetts$228,000–$342,000 / yearAt Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. This role ensures technologies deployed by Product, Data, and Engineering teams are aligned to enterprise architecture, interoperable across systems, and built for long-term scale.
Associate Director, GMP Operational Quality (Biologics And Devices) Vertex Pharmaceuticals, IncAssociate Director, GMP Operational Quality (Biologics And Devices)Boston, MA$94,600–$141,800 / yearThe successful candidate will be a key member of the Vertex Biologics and Devices Quality Team, influencing cross-functional alignment, proactively managing risk, and providing timely quality direction in support of external drug substance manufacturing and disposition. Key Duties and Responsibilities: Lead cross-functional collaboration with Manufacturing, Quality Control, MSAT, Regulatory Affairs, and other Quality functions to resolve complex deviations and align decisions with patient safety, product quality, and regulatory compliance.
Director, Regulatory Affairs CMC Vertex Pharmaceuticals, IncDirector, Regulatory Affairs CMCBoston, MA$190,400–$285,600 / yearGeneral Summary: The Director, Chemistry Manufacturing Controls (CMC) leads a Regulatory CMC team responsible for developing and executing global regulatory strategies across multiple investigational and commercial products in the small molecule portfolio. This role provides strategic leadership for complex regulatory CMC activities, oversees Health Authority engagement, and ensures regulatory requirements are effectively integrated into development and commercialization plans.
Director, Global Submission Management Vertex PharmaceuticalsDirector, Global Submission ManagementBoston, Massachusetts$190,400–$285,600 / yearThis role partners closely with Major Submission Leads, Global Regulatory Strategy, Regulatory CMC, Labeling, Publishing, and Advertising & Promotion functions to support coordinated submission planning, execution consistency, and steady‑state portfolio throughput. Demonstrates the ability to effectively adopt and leverage emerging technologies, including AI driven tools, and maintains a continuous learning mindset to strengthen GSM decision-making and operational efficiency.
Human Resources Business Partner Senior Director Vertex PharmaceuticalsHuman Resources Business Partner Senior DirectorBoston, Massachusetts$227,200–$340,800 / yearStrategic Workforce Planning: Drive strategies to attract, develop, and retain high-quality technical and leadership talent, proactively closing capability gaps through targeted build/buy/borrow approaches, internal mobility and upskilling/reskilling pathways as roles evolve with AI, and location strategies that expand access to scarce talent while balancing cost, speed, and business needs, supported by focused retention actions for critical roles. Executive Coach and Developer: Elevate leadership and team performance by coaching the senior leaders, designing and facilitating a structured leadership team journeys that strengthens cohesion, decision quality, prioritization, and accountability, and leading rigorous talent reviews and succession planning that build continuity and deepen pipelines for critical roles.
Clinical Development Associate Medical Director- Pain Vertex Pharmaceuticals, IncClinical Development Associate Medical Director- PainBoston, MA$204,000–$306,000 / yearParticipates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, IND safety reports and annual reports for assigned trials, responses to regulatory authorities and Ethics Committees/IRBs, and other documents as appropriate. Provides scientific and clinical input to study-related documents and analysis plans including informed consent forms, clinical research forms, statistical analysis plans, clinical pharmacology analysis plans, and clinical study reports.
Clinical Development Medical Director- Pain Vertex PharmaceuticalsClinical Development Medical Director- PainBoston, Massachusetts$240,000–$360,000 / yearThe Clinical Development Medical Director will serve as the Medical Lead for Vertex clinical trials, working with cross-functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. Provides scientific and clinical input to study-related documents and analysis plans including Informed consent forms (ICF), clinical research forms (CRF), statistical analysis plans (SAP), clinical pharmacology analysis plans (CPAP), and clinical study reports (CSR).
Associate Director, Global Submission Management Vertex PharmaceuticalsAssociate Director, Global Submission ManagementBoston, Massachusetts$163,200–$244,800 / yearThis role partners closely with Major Submission Leads, Global Regulatory Strategy, Regulatory CMC, Labeling, Publishing, and Advertising & Promotion functions to support coordinated submission planning, execution consistency, and steady‑state portfolio throughput. Demonstrates the ability to effectively adopt and leverage emerging technologies, including AI driven tools, and maintains a continuous learning mindset to strengthen GSM decision-making and operational efficiency.
Associate Director, Commercial Operations Field Strategy & Execution Vertex Pharmaceuticals, IncAssociate Director, Commercial Operations Field Strategy & ExecutionBoston, MA$164,000–$246,000 / yearServing as a critical link between strategy and execution, the Associate Director will collaborate across Commercial Operations teams and other cross-functional and technical stakeholders to ensure seamless delivery, drive business performance, and improve the overall field experience. This role will partner closely with business and field leadership to enhance field effectiveness by ensuring appropriate resourcing, clear communication, and strong support across field-facing initiatives.
Health Economics & Outcomes Research Associate Director, Pain Vertex Pharmaceuticals, IncHealth Economics & Outcomes Research Associate Director, PainBoston, MA$176,000–$264,000 / yearKey Duties and Responsibilities: Leads others to execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Biostatistics Associate Director (HYBRID) Vertex PharmaceuticalsBiostatistics Associate Director (HYBRID)Boston, Massachusetts$174,800–$262,200 / yearBiostatistics Associate Director will perform sophisticated scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with minimal guidance and mentoring on new and complex issues. Develops Cross-functional Data Review (xFDR) plan, Key Reports Memo (KRM), and Data Dissemination Plan (DDP) in order to facilitate the review, summary, and dissemination of key study data/results.
Associate Director, Quality Systems - Cell and Gene Therapies (VCGT) Vertex PharmaceuticalsAssociate Director, Quality Systems - Cell and Gene Therapies (VCGT)Boston, Massachusetts$148,000–$222,000 / yearThe Quality Systems Associate Director supports strategicdesignofand ensures tactical execution of quality systems, risk management, and quality culture across the Vertex Cell and Gene Therapy (VCGT) organization. Responsible for strategic, Risk Management monitoring support, and Data Integrity initiatives and activities to drive prioritization and in-support continuous improvement across VCGT QMS/Compliance processes .
Field Medical Director Vertex PharmaceuticalsField Medical DirectorBoston, Massachusetts$252,000–$378,000 / yearThrough these activities, the Field Medical Director is integral to achieving Vertex scientific communication objectives and that external clinical perspectives are effectively reflected in strategic priorities including evidence generation priorities and medical education planning. The Field Medical Director (Nephrology) is a key member of the Vertex Medical Affairs team providing a real‑world clinical practice perspective to Medical Affairs by delivering high‑quality scientific and clinical engagement with key stakeholders.
Executive Director, Data & Methods (Data And Computational Sciences) Vertex Pharmaceuticals, IncExecutive Director, Data & Methods (Data And Computational Sciences)Boston, MA$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers - building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Associate Director, Digital Marketing - HCP Vertex PharmaceuticalsAssociate Director, Digital Marketing - HCPBoston, Massachusetts$162,800–$244,200 / yearThe Associate Director, Digital Marketing HCP will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with healthcare professionals (HCPs) within the US Kidney Business Unit. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Associate Director, Talent Acquisition Vertex PharmaceuticalsAssociate Director, Talent AcquisitionBoston, Massachusetts$146,400–$219,600 / yearDemonstrates digital and AI fluency, with proven ability to leverage AI-powered tools and digital platforms across the recruiting lifecycle including sourcing, screening, and candidate engagement to enhance talent intelligence, interpret labor market data, and support data-driven hiring decisions. Track milestones and timelines across projects, analyzing and communicating project risks and issues as necessary, making adjustments to project plans, timelines or resources to ensure successful project delivery.
Senior Director, Finance Integration Lead Vertex Pharmaceuticals, IncSenior Director, Finance Integration LeadBoston, MA$212,000–$318,000 / yearThis role will oversee the financial strategy, execution, and outcomes of M&A integrations, ensuring that cross-functional value capture assumptions, financial considerations, and integration-related commitments are clearly baselined, tracked, governed, and supported throughout the integration. Partner closely with Vertex and acquiring company's Finance, HR, Accounting, and other key stakeholders on finance integration activities, including key coordination points related to systems, financial data flows, and reporting consistency.
Health Systems Marketing Associate Director, Pain Vertex PharmaceuticalsHealth Systems Marketing Associate Director, PainBoston, Massachusetts$162,800–$244,200 / yearThis role will develop high impact personal and digital promotional content and work closely with colleagues on the health systems marketing team, US market access team, Health Economics and Outcomes Research team, HCP marketing team, and strategic accounts team. Collaborate with cross-functional partners within strategic accounts, market access and HCP marketing to ensure strategic alignment, operational efficiency, and collaborative strategies & tactics where appropriate.
Senior Director, Global Medical Affairs - Nephrology Vertex PharmaceuticalsSenior Director, Global Medical Affairs - NephrologyBoston, Massachusetts$252,000–$378,000 / yearExcellent understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with key external stakeholders (e.g., healthcare providers, payers, advocacy bodies). This role will work closely with a cross-functional group to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs and will ensure the flawless execution of Nephrology medical plans.
Executive Director, Data & Methods (Data and Computational Sciences) Vertex PharmaceuticalsExecutive Director, Data & Methods (Data and Computational Sciences)Boston, Massachusetts$270,600–$406,000 / yearThis leader will set AI and computational strategy that spans the full breadth of modern drug discovery and scientific therapeutic development; and will translate vision into scalable platforms, methods, and tools that serve every modality and measurably speed up discovery and translation, through the development of cutting-edge methods that leverage critical proprietary and public data to drive impact across our global research portfolio. Lead a multidisciplinary organization of scientists, engineers, and managers — building structure, growing other leaders, and driving organizational effectiveness as a leader of leaders.
Associate Director, HCP Experience - US Pain Vertex Pharmaceuticals, IncAssociate Director, HCP Experience - US PainBoston, MA$162,800–$244,200 / yearThe Associate Director, HCP Experience will play a critical role in shaping and delivering best-in-class experiences for healthcare professionals (HCPs) as we continue the launch of JOURNAVX, a novel selective pain signal inhibitor of NaV1.8 in acute pain. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Associate Director, Quality Systems - Cell And Gene Therapies (Vcgt) Vertex Pharmaceuticals, IncAssociate Director, Quality Systems - Cell And Gene Therapies (Vcgt)Boston, MA$148,000–$222,000 / yearThe Quality Systems Associate Director supports strategic design of and ensures tactical execution of quality systems, risk management, and quality culture across the Vertex Cell and Gene Therapy (VCGT) organization. Responsible for strategic, Risk Management monitoring support, and Data Integrity initiatives and activities to drive prioritization and in-support continuous improvement across VCGT QMS/Compliance processes.
Modeling & Simulations Associate Director Vertex Pharmaceuticals, IncModeling & Simulations Associate DirectorBoston, MA$168,000–$252,000 / yearGeneral Summary: The Modeling & Simulations Associate Director will be responsible for developing and executing M&S strategies and activities in cross functional drug development project teams in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D. Typically requires the following: PhD and 6 years experience or Master's Degree and 10 years experience in the application of Pharmacometric and other Modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies.
Associate Director, HCP Experience – US Pain Vertex PharmaceuticalsAssociate Director, HCP Experience – US PainBoston, Massachusetts$162,800–$244,200 / yearThe Associate Director, HCP Experience willplay a critical role in shaping and delivering best-in-class experiences for healthcare professionals (HCPs) as we continue the launch of JOURNAVX, a novel selective pain signal inhibitor of NaV1.8 in acute pain. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Biostatistics Associate Director (Hybrid) Vertex Pharmaceuticals, IncBiostatistics Associate Director (Hybrid)Boston, MA$174,800–$262,200 / yearGeneral Summary: Biostatistics Associate Director will perform sophisticated scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with minimal guidance and mentoring on new and complex issues. Develops Cross-functional Data Review (xFDR) plan, Key Reports Memo (KRM), and Data Dissemination Plan (DDP) in order to facilitate the review, summary, and dissemination of key study data/results.
Health Economics & Outcomes Research Associate Director, Cell & Gene Therapy Vertex PharmaceuticalsHealth Economics & Outcomes Research Associate Director, Cell & Gene TherapyBoston, Massachusetts$176,000–$264,000 / yearLeads others to execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value. The Health Economics & Outcomes Research Associate Director, Cell and Gene Therapy (CGT) will participate in leading the development and execution of HEOR studies in support of Vertex's CGT products, including in hemoglobinopathies and type 1 diabetes.
Senior Director, Business Operations Lead - Small Molecule, Commercial Manufacturing and Technical Operations Vertex Pharmaceuticals IncSenior Director, Business Operations Lead - Small Molecule, Commercial Manufacturing and Technical OperationsBoston, MAReporting to the Executive Director, Business Operations and Performance, this role is accountable for product-level business leadership across commercial manufacturing activities, with a primary focus on CDMO business management, manufacturing performance governance, readiness and growth planning, cost of goods oversight, and scenario-based business decision support. Lead and support commercial manufacturing scenario planning in support of DST, enterprise, and manufacturing assessments, including scenarios driven by scale, geopolitical changes, supply risk, or evolving business strategy.
Digital Media Analytics, Associate Director - Kidney Business Unit Vertex Pharmaceuticals, IncDigital Media Analytics, Associate Director - Kidney Business UnitBoston, MA$157,800–$236,600 / yearIf you've successfully optimized digital media budgets, held publishers accountable for on-budget, quality audience acquisition and translated complex data into actionable marketing strategy, we want to talk. Vertex is launching innovative therapies in our Kidney Business Unit, and we need a strategic digital media analytics leader to drive measurement, optimization, and agency accountability across our DTC and HCP marketing campaigns.
Associate Director, GMP Operational Quality (Biologics and Devices) Vertex PharmaceuticalsAssociate Director, GMP Operational Quality (Biologics and Devices)Boston, Massachusetts$94,600–$141,800 / yearThe successful candidate will be a key member of the Vertex Biologics and Devices Quality Team, influencing cross-functional alignment, proactively managing risk, and providing timely quality direction in support of external drug substance manufacturing and disposition. Lead cross-functional collaboration with Manufacturing, Quality Control, MSAT, Regulatory Affairs, and other Quality functions to resolve complex deviations and align decisions with patient safety, product quality, and regulatory compliance.
Executive Director, Msat - Type 1 Diabetes Vertex Pharmaceuticals, IncExecutive Director, Msat - Type 1 DiabetesBoston, MA$249,400–$374,200 / yearYou will build and lead a high-performing MSAT organization that bridges Process Development and GMP Manufacturing, ensuring processes are robust, scalable, compliant, and inspection-ready from early clinical supply through commercialization. This role is accountable for process performance, technical transfer, validation, continued process verification, comparability, and lifecycle management-with a particular focus on external manufacturing partners (CMOs).
Senior Director, Business Operations Lead – Small Molecule, Commercial Manufacturing and Technical Operations Vertex PharmaceuticalsSenior Director, Business Operations Lead – Small Molecule, Commercial Manufacturing and Technical OperationsBoston, Massachusetts$218,400–$327,600 / yearReporting to the Executive Director, Business Operationsand Performance, this role is accountable for product-level business leadership across commercial manufacturing activities, with a primary focus on CDMO business management, manufacturing performance governance, readiness and growth planning, cost of goods oversight, and scenario-based business decision support. Lead and support commercial manufacturing scenario planning in support of DST, enterprise, and manufacturing assessments, including scenarios driven by scale, geopolitical changes, supply risk, or evolving business strategy.
Executive Director, Biotherapeutics Dmpk Vertex Pharmaceuticals, IncExecutive Director, Biotherapeutics DmpkBoston, MA$268,000–$402,000 / yearGeneral Summary: We are seeking an accomplished and strategic leader to serve as Executive Director, Biotherapeutics DMPK-Bioanalysis (DMPK-BA), to guide the DMPK-BA strategy for our rapidly growing Biotherapeutics portfolio that includes protein, antibody, ADC, and cell and genetic therapies. The ideal candidate will bring deep strategic and scientific expertise in DMPK-BA for one or more biotherapeutic modalities described above, have demonstrated record of people management and leadership in a direct line as well as matrixed environment, and will have the ability to influence cross-functional teams and governance bodies at Vertex.