Key Responsibilities: Defining and executing model-based development strategies for oncology projects Planning, conducting and reporting exposure-response analysis, simulation-based trial design and dose selection, and population PK modelling Applying innovative methods such as drug-disease modeling, longitudinal exposure-response analysis, model-based meta-analysis, quantitative systems pharmacology and AI/ML informed analyses to enhance data use and trial efficiency Presenting strategy and defending outcome of model-based approaches to internal governance boards and regulatory agencies Contributing to clinical program design, trial protocols, analysis plans, study reports and regulatory submissions Write or review clinical pharmacology components of regulatory documents and responses such that GSK products are rapidly and efficiently approved with optimum labelling (with regards to the clinical pharmacology, modelling and simulation contents) Implement best practices, trends, lessons learned from internal and external sources to further clinical pharmacology modelling and simulation contributions to R&D pipeline Ability to interact with line and middle management, staff and external contacts on a functional, strategic and tactical level Promoting model-informed drug discovery and development through external collaboration, journal publication and conference presentation Why you? Site Name: USA - Pennsylvania - Upper Providence, USA - Massachusetts - Waltham, USA - North Carolina - Durham Posted Date: May 1 2026 Company Overview At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade.