| Location | San Francisco, CA |
Senior Staff AI Engineer, Agentic AI
Location: Bay Area - Oakland, CA
Employment Type: Full-time
Experience: 8–15 years
Focus: Agentic AI, Scientific Reasoning, AI Harnesses, Tool Use, Memory, Evaluation Systems
About Our Client
Our client is building the first AI-native operating system for materials science.
Their platform helps scientists, chemists, and R&D teams reason through complex scientific problems using AI-native workflows, proprietary scientific data, and agentic systems designed for real-world research environments.
The company is working with a uniquely valuable scientific data foundation, including trillions of proprietary scientific tokens that are not available anywhere else. This creates a rare opportunity to build AI systems that understand how scientists think, work, and make decisions.
About the Role
Our client is hiring a Senior Staff AI Engineer to own the technical direction of the agentic AI harness at the center of the platform.
This is the most senior hands-on individual contributor role on the Agentic AI team. This person will define how the product evolves from a chat-based experience into an agentic-first platform where AI agents can reason, plan, use tools, remember context, evaluate outcomes, and operate across the full scientific workflow.
This is a true 0-to-1 role. You’ll build the orchestration, tool use, memory, planning, and reasoning layer for production agent systems while helping lead two junior engineers on the AI harness. You’ll also partner closely with product and ML leadership to expand agent capabilities across every surface of the platform.
What You’ll Do
Own the technical direction for the agentic AI harness
Build and expand production agent systems for scientific and chemistry workflows
Design orchestration, tool use, memory, planning, and evaluation layers for agentic systems
Help shift the platform from a chat-style interface into an agentic-first experience
Build tools and sub-agent personas that reflect how chemists think and work
Integrate frontier reasoning models into the application
Expand agent capabilities across scientific workflows and product surfaces
Contribute to potential fine-tuning programs for domain-specific scientific reasoning
Make agent behavior observable, measurable, and reliable through tracing and evaluation systems
Evaluate agent performance against real scientific tasks
Drive agent reliability to the level where customers can trust agents to act with increasing autonomy
Provide technical leadership to junior engineers on the AI harness team
Partner closely with product, ML, and engineering leadership on roadmap and architecture
What We’re Looking For
8–15 years of experience in AI engineering, software engineering, ML engineering, or related technical roles
Staff-level or Senior Staff-level experience setting technical direction, not just executing tasks
Experience building sophisticated production agent systems from inception through scale
Experience building an agent harness or similar agentic infrastructure
Hands-on experience with low-level agentic frameworks such as LangGraph, LangChain, or equivalent tools
Strong full-stack programming experience across Python, React, TypeScript, or similar technologies
Deep understanding of LLMs, agent orchestration, tool use, memory, planning, evaluation, and production reliability
Ability to design systems that move beyond chat into autonomous or semi-autonomous workflows
Strong judgment around system architecture, model behavior, observability, and product safety
Experience working in a startup, or a background combining big tech experience with startup execution
Ability to lead technically while remaining deeply hands-on
Technical Environment
Relevant technologies and concepts include:
Python
LangGraph
LangChain
Agentic frameworks
Frontier LLMs, including GPT-4, Claude, and similar models
Braintrust
Tracing and evaluation systems
RAG
React
TypeScript
Tool use
Memory systems
Agent orchestration
Scientific reasoning systems
Preferred Background
Our client is especially interested in candidates with:
A degree in science, engineering, computer science, or a related technical field
Master’s or PhD from a strong technical university
Scientific background or professional exposure to chemistry, physics, biology, materials science, or mechanical engineering
Experience fine-tuning reasoning models
Experience building AI systems for scientific reasoning
Experience working with proprietary datasets or domain-specific AI systems
Experience mentoring or leading junior engineers while staying hands-on
Why This Opportunity
Own the agentic AI layer at the center of an AI-native scientific platform
Build agent systems for real chemistry and materials science workflows
Work with proprietary scientific data that no one else has access to
Help define how scientists and AI reason together
Move a platform from chat-based AI into agentic-first workflows
Partner directly with product and ML leadership on company-defining technical direction
Step into a Senior Staff-level role with broad technical ownership and meaningful product influence
Build at the intersection of frontier LLMs, agentic systems, scientific reasoning, and enterprise R&D
Ideal Candidate Profile
The ideal candidate is a Senior Staff-level AI engineer who has already built production agent systems and knows what it takes to move them beyond version one.
They are deeply hands-on, technically opinionated, and capable of setting direction across agent orchestration, memory, tool use, evaluation, tracing, and product integration. They understand that reliable agent behavior requires more than model calls — it requires systems, feedback loops, observability, and strong product judgment.
This person should be excited by the opportunity to build AI systems that help scientists reason, discover, and work in fundamentally new ways.