Senior Manager, ARD Instrument Systems

Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that change patients' lives. Central to this mission is our Research and Development team, which is dedicated to translating advanced science and cutting-edge technologies into the therapies and vaccines that matter most. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage innovative design and process development capabilities to accelerate the delivery of best-in-class medicines to patients around the globe. 

What You Will Achieve

The Manager, Instrument Systems is responsible for personally conducting while also leading a team of instrument systems professionals who support the lifecycle management, operational performance, and continuous improvement of Biotherapeutics Pharmaceutical Sciences ARD GxP-regulated laboratory systems. The role ensures that instrument systems remain compliant, reliable, inspection-ready, and aligned with business and regulatory requirements while enabling efficient scientific and operational execution.

This position provides direct oversight on the execution, strategic and day-to-day leadership for instrument systems operations, data integrity oversight, and cross-functional stakeholder engagement. The manager is accountable for prioritizing team activities, removing barriers, establishing governance, driving standardization, and building organizational capabilities that support sustainable business growth and operational excellence.

The role serves as a key liaison between Quality, Global Workplace Experience, Digital, Validation, and Scientific functions to ensure instrument-related risks are proactively managed, regulatory requirements are met, and continuous improvement opportunities are identified and implemented.

Role Responsibilities

• Lead and develop a team responsible for instrument systems lifecycle management, ensuring effective prioritization, resource allocation, performance management, and talent development.
• Provide strategic oversight of instrument systems compliance, data integrity, computerized system controls, and adherence to applicable GMP, GxP, regulatory, and company requirements.
• Establish and maintain inspection-ready processes, ensuring support for internal audits, regulatory inspections, quality assessments, and remediation activities.
• Drive governance and oversight of instrument-related quality systems, including CAPAs, changes, risk assessments, and life cycle documentation.
• Partner with Quality, GWE, Digital, and BTx ARD organizations to prioritize work, resolve issues, remove roadblocks, and ensure business continuity.
• Develop and maintain procedures, standards, work practices, and documentation supporting the instrument systems program and compliance framework.
• Lead training strategy and competency development for instrument systems personnel, ensuring knowledge transfer, qualification, and ongoing capability building.
• Identify, prioritize, and implement continuous improvement initiatives that enhance compliance, reliability, system performance, user experience, efficiency, and scalability across the instrument systems organization.

Here Is What You Need (Minimum Requirements)

• BS degree in Biology, Chemistry, or related field with 6+ years of experience in a GMP laboratory or similar field; MS degree with 5+ years, or PhD with 1+ years
• Significant experience supporting regulated laboratory, manufacturing, or quality environments.
• Demonstrated leadership experience managing technical, quality, compliance, or instrument systems teams.
• Experience with regulated computerized systems, validation, and data integrity programs.
• Experience supporting audits/inspections on the topic of instrument lifecycle.
• Experience implementing operational excellence and continuous improvement initiatives.
• Strong understanding of pharmaceutical, biotechnology, or regulated healthcare environments.

Bonus Points If You Have (Preferred Requirements)

• Experience supporting research, development, laboratories, quality, manufacturing, or technical organizations.
• Experience leading enterprise compliance, quality transformation, governance, or continuous improvement initiatives.
• Experience supporting digital quality transformations, eQMS implementations, or AI-enabled compliance solutions.
• Experience partnering with Quality Assurance, GWE, and Digital.
• Demonstrated success leading organizational change and capability-building efforts.

PHYSICAL/MENTAL REQUIREMENTS

Position requires occasional light lifting and periods of standing, sitting or walking.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Some occasional travel to other Pfizer sites is possible. 

Additional Information:

• Work Location Assignment: On Premise
• Last Day to Apply: November 2, 2026

The annual base salary for this position ranges from $116,000.00 to $193,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

Research and Development