SD_Scientist I

The successful candidate will support the analytical characterization of novel lipid nanoparticle (LNP)-based therapeutics and collaborate with cross-functional teams in a fast-paced research environment. Key Responsibilities Perform quantitative analysis of lipid nanoparticles (LNPs) encapsulating nucleic acids under the guidance of Analytical Scientists.

Position: Scientist I
Location: San Diego, CA 92111 (Poseida)
Contract Duration: 12 Months (Potential for Extension or Full-Time Conversion)
Pay Rate: $27.96 - $44.82/hour (W2)
Benefits: Weekly Pay, Medical, Dental, and Vision Insurance
 
Position Overview
Our client is seeking a highly motivated Scientist I to join the Gene Therapy team in San Diego, CA. This is an exciting opportunity to contribute to the development of innovative non-viral nucleic acid delivery technologies for in vivo and ex vivo genome editing and gene therapy applications. The successful candidate will support the analytical characterization of novel lipid nanoparticle (LNP)-based therapeutics and collaborate with cross-functional teams in a fast-paced research environment.
 
Key Responsibilities

• Perform quantitative analysis of lipid nanoparticles (LNPs) encapsulating nucleic acids under the guidance of Analytical Scientists.
• Analyze raw materials used in LNP formulations to ensure quality and consistency.
• Evaluate the relationship between the physicochemical properties of experimental nanoparticle formulations and their efficacy and safety.
• Maintain accurate, detailed, and organized analytical records and experimental documentation.
• Collaborate closely with cross-functional teams to support research and development activities.
• Assist with routine laboratory operations, including supply ordering, instrument calibration, and maintenance of laboratory schedules.

 
Qualifications

• Bachelor's or Master's degree in Pharmaceutical Sciences, Bioengineering, Chemical Engineering, Chemistry, or a related scientific discipline.
• 0–2 years of relevant industry or academic laboratory experience (or an equivalent combination of education and experience).

 
Preferred Skills & Experience

• Hands-on experience with analytical techniques such as:
  • RiboGreen assays
  • Dynamic Light Scattering (DLS)
  • Zeta Potential measurements
• Experience with High-Performance Liquid Chromatography (HPLC) is strongly preferred.
• Familiarity with additional analytical characterization techniques is a plus.
• Experience preparing and formulating laboratory buffers.
• Strong attention to detail with the ability to generate accurate, reproducible results.
• Proficiency in Microsoft Excel; experience with data analysis software such as GraphPad Prism or JMP is desirable.
• Excellent verbal and written communication skills.
• Strong organizational skills with the ability to manage multiple priorities while working effectively in a collaborative team environment.

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