Scientist, Proteins, Analytical Development

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression . Purpose: The Therapeutics, Development & Supply (TDS), Proteins Analytical Development (AD) is recruiting for a Scientist who will conduct peptide mapping method development and qualification activities on monoclonal antibodies, bi- and tri-specific antibodies and antibody drug conjugates.

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com .

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Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

All Job Posting Locations:
Malvern, Pennsylvania, United States of America

Job Description:

About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Scientist, Proteins, Analytical Development.

Purpose: The Therapeutics, Development & Supply (TDS), Proteins Analytical Development (AD) is recruiting for a Scientist who will conduct peptide mapping method development and qualification activities on monoclonal antibodies, bi- and tri-specific antibodies and antibody drug conjugates.

You will work and grow in an environment that values innovation, leadership, scientific excellence, urgency, and personal accountability.

You will be responsible for:

• Operate state-of-the-art LC and MS instrumentation
• Learn and apply different software packages for LCMS/protein analysis
• Perform LCMS-based quantitation of post-translational modifications
• Design and implement peptide mapping / MS experiments on antibodies and recombinant proteins to assess sequence coverage and sites of modification
• Participate in IND, IMPD, BLA, and other regulatory filings
• Develop test methods, provide documentation and write scientific reports.
• Conduct testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
• Lead or facilitate technical discussions and participate in cross-functional teams at project-related meetings

Qualifications / Requirements:
Education:

• A master's degree with 5+ years, or a bachelor's degree with 9+ years of relevant biochemical experience

Experience and Skills:

Required:

• Proven scientific expertise with extensive hands-on experience with LC-MS

• Knowledge of method robustness, method design and familiarity with assay validation parameters
• Excellent organization, communication, presentation skills and scientific/technical writing skills

• Proficiency at running and trouble-shooting assays

• Able to manage multiple tasks, handle tight timelines and deliver quality data

Preferred:

• Experience peptide mapping method development and qualification activities on monoclonal antibodies, bi- and tri-specific antibodies and antibody drug conjugates
• Excellent interpersonal skills

• Experience with commercialization of therapeutic proteins

• An understanding and experience in the application of various GXP concepts
• Experience preparing reports, protocols and SOPs

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

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Required Skills:

Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression