Scientist II, Radiopharmacology

Position Title: Scientist II, Radiopharmacology

Reporting Location: Rockville, MD

Reports To: Head of Radiopharmacology

DUTIES, RESPONSIBILITIES:

• Design and execute radiolabeling reactions using a range of isotopes, including Lu-177, Ac-225, In-111, Zr-89, At-211, I-131, and Pb-212.
• Perform conjugation reactions between bifunctional chelators and peptides, proteins, antibodies, or other biological molecules.
• Develop, optimize, and troubleshoot radiochemical synthesis and radiolabeling protocols for both diagnostic and therapeutic applications.
• Conduct quality control and stability testing of radiolabeled compounds using appropriate analytical methods.
• Analyze experimental data, interpret results, and communicate findings to cross-functional teams.
• Support the design, execution, analysis, and interpretation of in vivo studies involving radiolabeled compounds.
• Develop, write, review, and maintain technical documents, including methods, SOPs, protocols, work instructions, and other documentation, in adherence to the Champions quality control system.
• Prepare, review, and ensure compliance of study protocols, technical reports, experimental procedures, and study-related documentation.
• Train and mentor junior staff in radiochemistry techniques, radiopharmacology procedures, radiation safety, quality control, and the safe handling of radioactive materials.
• Maintain accurate, complete, and traceable laboratory records, including experimental procedures, calculations, analytical results, and instrument records.
• Stay current with advancements in radiochemistry, radiopharmacology, molecular imaging, targeted radionuclide therapy, and nuclear medicine.
• Assist in the evaluation, validation, implementation, and routine use of new laboratory equipment, automation systems, analytical tools, and technologies.
• Collaborate with internal scientific teams, project managers, laboratory operations, and other cross-functional groups to support successful study execution.
• Assist with troubleshooting radiochemistry, formulation, analytical, and study-related issues as needed.
• Support laboratory organization, radioactive material management, and appropriate handling and disposal of radioactive waste in accordance with established procedures.
• Perform additional duties as assigned, either verbally or in writing, at any time.