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The Technician II (Purification) is responsible for purifying custom oligonucleotides according to the customer's order. This generally includes the sorting, purification, and QC sampling of the products being made.
This position reports to the Supervisor (Purification) and is part of the Purification Value Stream located in San Diego, CA and will be an on-site role (Monday - Friday, 6am - 3pm).
In this role, you will have the opportunity to:
- Synthesize custom oligonucleotides
- Purify oligos using ion-exchange and reverse phase methods
- Measure quality using optical density, mass spectrometry, and capillary electrophoresis
The essential requirements of the job include:
- Adheres to safety regulations, lab SOPs, and contamination controls
- Synthesizes custom oligonucleotides on various platforms
- Performs the purification of oligos using various techniques
- Uses automated and manual lab equipment including limited maintenance and troubleshooting activities
- Quantifies and samples oligos for quality control tests
- Assesses QC data accurately and assigns pass/fail dispositions for oligos
- Ensures that product meets final purity guarantees through the custom purification process
- Sorts oligos for the proper purification method using software
- Troubleshoots oligo failures and makes thoughtful sorting and purification decisions
- Follows and records process steps accurately
- Demonstrates behavior consistent with the Integrated DNA Technologies Core Values
- Performs other duties as assigned
Education:
- Associate's (2 year) degree or comparable combination of education and experience required
- Bachelor's (4 year) degree in a science related field (Biology, Chemistry, etc.) preferred
Experience:
- Proficiency in a variety of PC software programs with strong working knowledge of Microsoft Office required
Other Job Qualifications
- Ability to work in a team environment, remaining attentive to ideas, recognizing responsibilities, and actively participating with others to accomplish assignments and achieve desired goals
- Strong attention to detail
- Ability to communicate with peers and all levels of management
- Ability to manage time and work independently
- Ability to prioritize and organize workload to efficiently accomplish departmental goals
- Uses aids and SOPs to make decisions about the proper production path per product
- Ability to perform under stress when confronted with emergent, critical, unusual, or dangerous situations
- Ability to perform a variety of duties, without loss of efficiency or composure
- Ability to maintain both a high standard of courtesy and cooperation in dealing with co-workers
- Ability to accept responsibility for the direction, control, or planning of an activity
- Adaptability to situations requiring the precise attainment of set limits, tolerances, or standards
- Ability to perform repetitive work regularly, including capping and labeling test tubes
Physical Requirements:
Exert 20-50 lbs. of force occasionally and/or 10-15 lbs. of force frequently
Constant (67%-100% of work day)
- Reaching: extending hand(s) and arm(s) in any direction.
- Using Fingers/Grasping/Feeling: writing or otherwise working, primarily with fingers rather than with the whole hand or arm as in handling. Applying pressure to an object with the fingers or palm and perceiving attributes of objects such as size, shape, temperature, or texture by touch.
- Talking: expressing or exchanging ideas by means of the spoken work - those activities in which they must convey detailed or important spoken instructions to other workers accurately, loudly, or quickly.
- Hearing: perceiving the nature of sounds at normal range; ability to receive detailed information through oral communication, and to make fine discriminations in sound, such as when auscultating and percussing.
- Repetitive Motion: substantial movements (motion) of the wrists, hands, and/or fingers.
Frequently (34-66% of work day)
- Sitting: to assume a position in which the weight is largely supported by the buttocks, usually with the body vertical and the thighs horizontal.
- Standing: maintaining an upright position.
- Walking: moving about on foot to accomplish tasks.
- Lifting: raising objects from a lower to a higher position or moving objects horizontally from position to position.
- Bending: bending body downward and forward by bending spine at the waist and/or bending leg; bending legs at knee to come to rest or kneel.
- Pushing/Pulling: using upper extremities to press against something with steady force to thrust forward, downward or outward/using upper extremities to exert force to drag, haul or tug objects in a sustained motion.
Occasional (33% or less of work day)
- Climbing: stairs, stools, ramps, ladders.
Visual Acuity:
- Work requires close vision, distance vision, peripheral vision, depth perception and ability to adjust focus
- Ability to read pertinent printed material and distinguish colors
- Ability to accurately read measurements on equipment
- Ability to prepare and read written documentation, using a computer
It would be a plus if you also possess previous experience in:
- Manufacturing
- Purification
- Quality Control