Research Associate II/ Senior Research Associate I

WHY WORK FOR ARCTURUS?

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a global late-stage clinical mRNA medicines and vaccines company with enabling technologies: (i) LUNAR lipid-mediated delivery, (ii) STARR mRNA Technology (sa-mRNA) and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus developed the first self-amplifying messenger RNA (sa-mRNA) COVID vaccine in the world to be approved. Arcturus has an ongoing global collaboration for innovative mRNA vaccines with CSL Seqirus, and a joint venture in Japan, ARCALIS, focused on the manufacture of mRNA vaccines and therapeutics. Arcturus' pipeline includes RNA therapeutic candidates to potentially treat ornithine transcarbamylase deficiency and cystic fibrosis, along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. Arcturus' versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics. Arcturus' technologies are covered by its extensive patent portfolio (over 400 patents and patent applications in the U.S., Europe, Japan, China, and other countries).

Arcturus Therapeutics is presently recruiting outstanding candidates with experience in the field of mRNA technologies and nanoparticle sciences. Our corporate culture is dynamic, diverse, and creative. We value collaboration and teamwork. We seek individuals to join us with a genuine passion for the science behind helping to cure disease and improve the lives of patients.

WHY WORK FOR ARCTURUS?

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a global late-stage clinical mRNA medicines and vaccines company with enabling technologies: (i) LUNAR lipid-mediated delivery, (ii) STARR mRNA Technology (sa-mRNA) and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus developed the first self-amplifying messenger RNA (sa-mRNA) COVID vaccine in the world to be approved. Arcturus has an ongoing global collaboration for innovative mRNA vaccines with CSL Seqirus, and a joint venture in Japan, ARCALIS, focused on the manufacture of mRNA vaccines and therapeutics. Arcturus' pipeline includes RNA therapeutic candidates to potentially treat ornithine transcarbamylase deficiency and cystic fibrosis, along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. Arcturus' versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics. Arcturus' technologies are covered by its extensive patent portfolio (over 400 patents and patent applications in the U.S., Europe, Japan, China, and other countries).

Arcturus Therapeutics is presently recruiting outstanding candidates with experience in the field of mRNA technologies and nanoparticle sciences. Our corporate culture is dynamic, diverse, and creative. We value collaboration and teamwork. We seek individuals to join us with a genuine passion for the science behind helping to cure disease and improve the lives of patients.

Position Summary:

The Research Associate II / Senior Research Associate will support the Analytical Development team by performing analytical testing, method development, and characterization of RNA-based drug substances, intermediates, and formulated drug products. This position supports multiple development programs, including early research through clinical development, by generating high-quality analytical data to enable process development, formulation development, stability studies, and product characterization.

The successful candidate will work in a collaborative, fast-paced environment and contribute to the development, optimization, qualification, and execution of analytical methods for nucleic acid therapeutics.

Essential Responsibilities:

• Perform analytical testing of RNA drug substances, intermediates, and formulated drug products using a variety of analytical techniques.
• Execute analytical methods including chromatography, electrophoresis, spectroscopy, fluorescence-based assays, particle characterization, and other physicochemical characterization techniques.
• Support development, optimization, troubleshooting, qualification, and transfer of analytical methods.
• Analyze, interpret, and summarize experimental data and communicate results to project teams.
• Maintain accurate laboratory documentation, electronic laboratory notebooks (ELNs), and technical reports in accordance with company documentation practices and ALCOA principles.
• Support laboratory equipment qualification, calibration, routine maintenance, and troubleshooting.
• Manage analytical reagents, reference standards, laboratory inventory, and sample tracking.
• Collaborate effectively with cross-functional teams, including Process Development, Formulation Development, Quality Control, and Manufacturing.
• Present scientific findings during team meetings.
• Perform additional responsibilities as assigned.

Primary Outcomes:

• Generate accurate, high-quality analytical data within project timelines.
• Independently execute routine analytical assays with minimal supervision.
• Support development and continuous improvement of analytical methods.
• Maintain high standards of laboratory documentation and data integrity.
• Contribute to efficient execution of analytical activities across multiple development programs.

Position Requirements:

• Education Required: Bachelor's degree in Chemistry, Biochemistry, Molecular Biology, Pharmaceutical Sciences, or related scientific discipline.
• Experience Required: Research Associate II: BS with 2+ years of relevant industry experience.
• Senior Research Associate: BS with 5+ years of relevant industry experience or MS with 2+ years of industry experience.

Preferred Qualifications:

• Experience supporting analytical development for biologics or nucleic acid therapeutics.
• Experience with HPLC/UPLC, CE, Fragment Analysis, UV-Vis spectroscopy, fluorescence assays, or related analytical techniques.
• Familiarity with analytical method development and qualification.
• Experience with electronic laboratory notebooks (ELN).
• Experience supporting stability studies and analytical characterization.
• Knowledge of GMP/GDP documentation practices is a plus.

Planning & Organizational:

• Experience analyzing scientific data and troubleshooting laboratory experiments.
• Ability to manage multiple priorities while maintaining data quality.
• Strong attention to detail and organizational skills.
• Ability to independently execute routine laboratory work while recognizing when guidance is needed.
• Proficiency with Microsoft Office and scientific software

Interpersonal/ Communication:

• Strong written and verbal communication skills.

• Excellent organizational and time management abilities.

• Ability to work independently and collaboratively in a multidisciplinary environment.

• Demonstrated scientific curiosity and willingness to learn new analytical techniques.

• Strong problem-solving skills and attention to detail.

• High level of integrity and commitment to data quality.

• WHAT WE OFFER

• Free variety of snacks and beverages

• Health and Wellness programs

• Referral Bonuses

• Company-sponsored FUN events

Arcturus is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics