The successful candidate will lead efforts to characterize protein-small molecule interactions and their functional consequences in cellular systems. Responsibilities will include expression and purification of recombinant proteins, quantitative analysis of ligand binding using techniques such as isothermal titration calorimetry (ITC), and evaluation of target engagement in live cells using NanoBRET-based assays. The candidate will also assess protein levels and degradation using Western blotting and luminescence-based methods, including the HiBiT system (Promega).
A Ph.D. degree in chemistry, biochemistry, biophysics, biology, or a related discipline.
Please email the PI (uttam.tambar@utsouthwestern.edu) and include a CV (with publications and contact information for 3 references listed) and a one page cover letter that includes:
A summary of your past research experiences and accomplishments.
Potential research questions you are excited about in the Tambar Lab and why you could be a great fit.
Your goals for your postdoctoral training period.
Your current long-term career goals and ideal time frame for the next steps.
Your potential start date.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
Benefits
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include: