Postdoctoral Fellow-MSH-32035-051

Job Title: Postdoctoral Fellow in Diabetes, Obesity and Metabolism Institute, Mount Sinai, NY

The lab of Dr. Romina Bevacqua, an early-career Principal Investigator in the Diabetes, Obesity and Metabolism Institute, is seeking a curious, motivated, Postdoctoral Fellow interested in performing transformative research on human diabetes and pancreatic islet biology.

The broader significance of the work in Bevacqua Lab is that diabetes affects over 400 million people worldwide and advancing our understanding of adult human islet functionality, will lead to development of novel approaches for the treatment of diabetic patients. More specifically, Bevacqua Lab is interested in studying:

1. The regulatory mechanisms driving human islet maturation:
2. The genetic basis for their dysregulation in disease:
3. The application of these findings towards -cell regeneration and replacement therapies.

These approaches will include implementation of novel genetic approaches in vivo to reverse diabetes, and will open new possibilities for the treatment of patients with diabetes.

To address these topics, the lab uses cellular biology, including genetics on pseudoislet organoids derived from non-diving human islets, molecular biology, Next-gen sequencing (CUT&RUN, RNA-seq, ATAC-seq, Mi-seq), FACS of different islet cell populations, functional studies, islet transplantation approaches, and imaging.

Responsibilities and Qualifications

Responsibilities:

• Design and perform research studies
• Perform high-throughput data analysis
• Prepare figures and manuscripts
• Apply for external fellowship competition
• Contribute to grant applications
• Supervise and train graduate students
• Present work at internal, local, national and international meetings
• Perform ongoing literature review to remain current with new procedures, computational tools and related research
• Propose new research directions based on the advances discussed in literature

Qualifications:

• Recent PhD in Cellular Biology, Diabetes, Genetics, Genomics, Molecular Biology, Biochemistry, Bioengineering, Bioinformatics, Computational Biology or related field
• Experience in molecular biology techniques and high-throughput experimental methods (preferred)
• Experience in cell culture and mice handling (preferred)
• Goal-oriented and self-motivated with excellent verbal and written scientific communication skills
• Excellent organizational and project management skills
• Strong problem-solving skills
• Able to work well in multidisciplinary and collaborative research environment
• A track record of conference presentations and first author peer-reviewed publications

How to Apply:

To apply for the position, please submit:

• 2 references
• Cover letter briefly describing candidate's research experience, major contributions to the field, research interests and fit for this position
• CV

Please submit your CV, cover letter and 2 letters of reference in a single PDF or Word document to romina.bevacqua@mssm.edu

About the Mount Sinai Health System:

The Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education.

Mission and Values:

Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it.

Equal Opportunity Employer:

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law.

Compensation:

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72,500 - $80,000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.