Postdoctoral Fellow- Dr. Miller

University of Alabama at Birmingham

  • Birmingham, AL
  • 4 days ago

    Highlights

    The fellow will work closely with investigators in pathology, neuro-oncology, neurosurgery, cancer biology, genomics, proteomics, and computational biology, with access to extensive patient-derived datasets, state-of-the-art molecular profiling technologies, and the O'Neal Comprehensive Cancer Center's resources. Research projects will involve integrative analysis of large-scale multiomic datasets generated from human tumors and experimental models, including bulk and single-cell transcriptomics, epigenomics, proteomics, and emerging spatial technologies.

    Numbers & Facts

    LocationBirmingham, AL

    Description

    Position Details

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    Position Information

    Job Title Postdoctoral Fellow- Dr. Miller Department Name 392303040 Neuropathology School/College Academic Joint Departments Job Description

    A postdoctoral position is available in the laboratory of C. Ryan Miller in the Department of Pathology at the University of Alabama at Birmingham (UAB). We seek a highly motivated computational scientist to develop and apply cutting-edge bioinformatics approaches to understand the molecular drivers of malignant brain tumors and identify new therapeutic opportunities.

    The successful candidate will join a collaborative and multidisciplinary research environment focused on gliomas and other central nervous system tumors. The fellow will work closely with investigators in pathology, neuro-oncology, neurosurgery, cancer biology, genomics, proteomics, and computational biology, with access to extensive patient-derived datasets, state-of-the-art molecular profiling technologies, and the O'Neal Comprehensive Cancer Center's resources.

    Research projects will involve integrative analysis of large-scale multiomic datasets generated from human tumors and experimental models, including bulk and single-cell transcriptomics, epigenomics, proteomics, and emerging spatial technologies.

    The position provides outstanding opportunities for scientific independence, high-impact publications, grant development, and career advancement in cancer genomics and computational biology.

    Required Qualifications

    Required Qualifications

    • PhD, MD/PhD, or equivalent doctoral degree in Bioinformatics, Computational Biology, Genomics, Systems Biology, Computer Science, or a related field.
    • Demonstrated experience with next-generation sequencing data analysis.
    • Proficiency in R, Python, and related computational languages.
    • Experience working in Linux and high-performance computing environments.
    • Experience with agentic coding practices.
    • Strong quantitative, analytical, and problem-solving skills.
    • Excellent written and verbal communication skills.

    Preferred Qualifications

    • Experience analyzing bulk RNA-seq and single-cell RNA-seq datasets.
    • Experience with epigenomic data analysis, including CUT&RUN, ChIP-seq, ATAC-seq, chromatin accessibility, or DNA methylation profiling.
    • Experience with proteomics data analysis, including mass spectrometry-based and non-mass spectrometry-based platforms.
    • Familiarity with multiomic data integration, machine learning, statistical genetics, or network biology approaches.
    • Knowledge of cancer biology, neuro-oncology, tumor evolution, or tumor microenvironment biology.
    • Experience utilizing public genomic and proteomic resources such as TCGA, CPTAC, GEO, Synapse, and cBioPortal.
    • Evidence of scientific productivity through peer-reviewed publications.

    Preferred Qualifications

    Posting Detail Information

    Posting Number PF1093P Open Date 08/19/2026 Close Date Open Until Filled Yes Nondiscrimination Statement

    UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.

    Special Instructions for the Position

    Interested candidates should submit:

    • Curriculum vitae
    • Cover letter describing research experience, computational expertise, and career goals
    • Contact information for three professional references

    Applications should be sent to:

    C. Ryan Miller, MD, PhD

    Department of Pathology

    University of Alabama at Birmingham

    Email:rmiller@uab.edu

    Pre-employment Background Check

    A pre-employment background check investigation is performed on candidates selected for employment.

    About University of Alabama at Birmingham

    Supplemental Questions

    Required fields are indicated with an asterisk (*).

      • Did you complete postdoctoral training at another institution? Please provide name of institution and duration of tenure (e.g., month/year-month/year)

    (Open Ended Question)

      • Did you complete postdoctoral training at UAB in Birmingham? Please provide duration of tenure (e.g., month/year-month/year)

    (Open Ended Question)

    Documents Needed to Apply

    Required Documents

    • Curriculum Vitae
    • Graduate Transcripts (Unofficial Only)

    Optional Documents

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