Manager, Order-to-Cash (O2C)

The Position

Arrowhead Pharmaceuticals is seeking a strategic and experienced Manager, Order-to-Cash (O2C) to help establish, lead, and scale the global O2C function in support of the company's first commercial product launch and future growth initiatives. This role is responsible for supporting the vision, strategy, governance, and execution of end-to-end commercial revenue cycle processes while ensuring operational excellence, scalable infrastructure, strong internal controls, and exceptional customer service.

As a key member of the Finance organization, the Manager will optimize O2C operations, develop cross-functional operating models, and serve as a trusted business partner to Commercial, Supply Chain, Market Access, Legal, Accounting, and external trading partners. The ideal candidate brings expertise in life sciences commercialization, commercial product launches, and finance transformation, with experience implementing processes, systems, and controls that support business growth and compliance.

This role is full-time onsite, 5 days a week in Verona, WI. 

Responsibilities

Strategy, Leadership & Business Partnership

• Support the development and execution of the global O2C strategy, operating model, and roadmap to support commercial product distribution and business growth.
• Build and enhance scalable processes and controls that support global expansion, new product launches, and increasing transaction complexity.
• Own O2C policies, performance metrics, and continuous improvement initiatives.

Commercial Launch & Operations

• Partner with Commercial, Market Access, and Finance leadership to develop customer onboarding, contracting, pricing administration, and customer service processes.
• Ensure commercial agreements, customer terms, rebate programs, and related activities are effectively operationalized and executed in compliance with company policies.

Systems, Transformation & Process Excellence

• Lead the implementation, optimization, and governance of O2C capabilities within Microsoft Dynamics 365 and related commercial systems.
• Define and execute automation initiatives utilizing EDI, workflow automation, system integrations, analytics, and emerging technologies.

Controls and Compliance

• Partner with Internal Audit and External Audit teams to maintain effective controls and ensure SOX compliance across all O2C activities.

Requirements

• Bachelor's degree in Finance, Accounting, Business Administration, Life Sciences, or a related field.
• Five years of progressive experience in O2C, Revenue Operations, Finance Operations, or Shared Services.
• Experience building, optimizing, and scaling O2C functions within biotechnology, pharmaceutical, medical device, or other highly regulated industries.
• Significant ERP implementation, optimization, or transformation experience, preferably with Microsoft Dynamics 365.
• Strong understanding of revenue cycle processes and SOX compliance requirements.
• Proven ability to work independently, prioritize competing priorities, and manage multiple projects and timelines.
• Excellent communication and interpersonal skills with the ability to influence across multiple levels of the organization.
• Intermediate to advanced proficiency in Microsoft Office applications, including Excel, Word, Outlook, and PowerPoint.

Preferred

• MBA or other relevant professional certification.
• Experience with chargebacks, rebates, distributor fee-for-service arrangements, and market access programs.