Lab Support IT administrator

Noblesoft Technologies

  • Wilmington, OH
  • 1 day ago

    Highlights

    Administer, support, maintain, and troubleshoot Windows-based laboratory workstations (Windows 7 through current supported versions) and associated infrastructure supporting analytical and manufacturing laboratory instruments. Technical Communication & Leadership: Translate complex technical concepts into business-focused language for laboratory personnel, quality organizations, managers, and executive leadership.

    Numbers & Facts

    LocationWilmington, OH

    Description

    Job Title: Lab Support IT administrator

    Location: Wilmington, OH 45177

    Laboratory Systems Administration

    • Administer, support, maintain, and troubleshoot Windows-based laboratory workstations (Windows 7 through current supported versions) and associated infrastructure supporting analytical and manufacturing laboratory instruments.
    • Install, configure, upgrade, patch, and maintain operating systems, instrument software, middleware, and supporting applications.
    • Manage complete lifecycle activities including provisioning, imaging, deployment, upgrades, migrations, validation support, and decommissioning.
    • Perform advanced hardware and software troubleshooting for instrument-attached workstations while minimizing laboratory downtime.
    • Coordinate upgrades, migrations, software releases, and system enhancements with laboratory personnel, validation teams, and equipment vendors.
    • Support business continuity, disaster recovery, and backup/recovery activities for laboratory systems.

    GxP Compliance, Validation & Data Integrity

    • Ensure laboratory systems operate in compliance with GMP, GLP, GCP, FDA, and other applicable regulatory requirements.
    • Support and maintain validated systems through established Computer System Validation (CSV) methodologies.
    • Author, review, and execute validation documentation as required which may include:
      • User Requirements Specifications (URS)
      • Functional Requirements Specifications (FRS)
      • Design Specifications
      • Risk Assessments
      • Installation Qualification (IQ)
      • Operational Qualification (OQ)
      • Performance Qualification (PQ)
      • Validation Summary Reports
      • Traceability Matrices
    • Maintain systems in a validated state through approved change control processes.
    • Support regulatory inspections, customer audits, quality audits, and compliance assessments.
    • Ensure compliance with:
      • FDA 21 CFR Part 11
      • EU Annex 11
      • ALCOA+ Data Integrity Principles
      • GAMP 5 methodologies
      • Corporate cybersecurity and quality standards

    Compliance Reporting, Assessments & Quality Systems

    • Perform and document periodic reviews and assessments of GxP systems to ensure ongoing compliance and operational effectiveness.
    • Generate and maintain:
      • Periodic System Reviews
      • Data Integrity Assessments
      • User Access Reviews
      • Audit Trail Reviews
      • Security Assessments
      • Technical Impact Assessments
      • Compliance Status Reports
    • Analyze system trends, audit findings, and operational performance data to identify compliance risks and improvement opportunities.

    Risk Assessment & Root Cause Analysis

    • Conduct technical and compliance risk assessments related to infrastructure, laboratory applications, instrument software, cybersecurity vulnerabilities, and system changes.
    • Evaluate risks affecting product quality, patient safety, data integrity, system availability, and regulatory compliance.
    • Lead investigations involving system failures, deviations, cybersecurity incidents, and compliance concerns.
    • Perform fault isolation, troubleshooting, and root cause analysis utilizing methodologies such as:
      • 5 Why Analysis
      • Fishbone Analysis
      • Root Cause Analysis (RCA)
      • Failure Mode and Effects Analysis (FMEA)
    • Develop corrective and preventive action plans (CAPAs) to address identified issues and prevent recurrence.
    • Document investigation findings, impact assessments, and remediation plans.

    Identity & Access Management:

    • Administer Active Directory environments supporting laboratory and regulated systems.
    • Design, implement, and maintain Organizational Units (OUs), security groups, delegated administration models, and authentication services in partnership with the corporate Active Directory team.
    • Develop and maintain Group Policy Objects (GPOs) supporting security baselines, workstation hardening, application controls, and laboratory compliance requirements.
    • Manage local workstation permissions, privileged accounts, service accounts, and role-based access controls.
    • Conduct periodic access reviews to verify appropriate user permissions and segregation of duties.
    • Ensure identity and access management processes comply with GxP and data integrity requirements.

    Cybersecurity & Endpoint Security:

    • Execute cybersecurity efforts supporting laboratory workstations and regulated systems.
    • Implement and support endpoint protection technologies including:
      • Antivirus solutions
      • Endpoint Detection and Response (EDR)
    • Assess cybersecurity risks associated with legacy operating systems and vendor-supported instrument software.
    • Develop and implement compensating controls for unsupported or restricted laboratory systems.
    • Support security monitoring, incident response, remediation activities, and vulnerability assessments.
    • Collaborate with Information Security teams to maintain secure laboratory environments while preserving validated system states.

    Networking, Infrastructure & Firewall Technologies:

    • Provide engineering and support for laboratory networks and infrastructure.
    • Demonstrate advanced knowledge of:
      • TCP/IP Networking
      • DNS
      • DHCP
      • VLANs
      • Routing and Switching
      • Network Segmentation
      • Wireless Technologies
      • Firewall Technologies
    • Support the troubleshooting network connectivity supporting laboratory instruments, workstations, servers, and integrated business systems.

    Third-Party Software & Technology Evaluation:

    • Assess third-party laboratory software, vendor applications, and supporting technologies for alignment with enterprise architecture, cybersecurity requirements, and regulatory expectations.
    • Evaluate technical specifications, software requirements, system architecture, and integration capabilities.
    • Identify security, compliance, operational, and supportability risks associated with proposed solutions.
    • Develop recommendations for software implementation, remediation, and lifecycle planning.
    • Partner with vendors and internal stakeholders to ensure compliance with corporate standards and industry best practices.

    Technical Communication & Leadership:

    • Translate complex technical concepts into business-focused language for laboratory personnel, quality organizations, managers, and executive leadership.
    • Present technical risks, compliance findings, system health assessments, and strategic recommendations to non-technical stakeholders.
    • Develop executive summaries, technical reports, assessment findings, and decision-support documentation.
    • Serve as a trusted technical advisor for laboratory operations, validation, quality, and business leadership.
    • Facilitate cross-functional collaboration between IT, Cybersecurity, Quality Assurance, Validation, Engineering, Operations, and external vendors.

    BASIC QUALIFICATIONS:

    Minimum Education:

    • Bachelor's degree in information technology, Computer Science, Engineering, Biotechnology, or a related technical discipline.
    • Equivalent combination of education and experience may be considered.

    Experience:

    • 5+ years of IT infrastructure, systems engineering, or systems administration experience.
    • 3+ years supporting regulated GxP systems within pharmaceutical, biotechnology, medical device, or life sciences organizations.
    • Experience supporting laboratory instrumentation and computerized systems validation.
    • Experience working within highly regulated environments subject to FDA and international regulatory requirements.

    Technical Knowledge/Skills Needed:

    Required:

    • Microsoft Windows administration (Windows 7 through current supported versions).
    • Advanced Active Directory administration.
    • Expert-level Group Policy Object (GPO) administration and troubleshooting.
    • Local permissions and privileged access management.
    • Endpoint security technologies and cybersecurity controls.
    • Vulnerability management and system hardening.
    • Networking technologies including TCP/IP, DNS, DHCP, VLANs, routing, and switching.
    • Firewall technologies and network segmentation.
    • PowerShell scripting and automation.
    • Backup, disaster recovery, and business continuity processes.
    • Risk assessment and root cause analysis methodologies.
    • Audit trail review and user access review processes.
    • Computerized System Validation (CSV) methodologies.
    • Data Integrity principles and regulatory compliance frameworks.

    Preferred:

    • VMware virtualization technologies.
    • Waters Empower, ThermoFisher Sample Manager, MODA-EM, or similar laboratory software platforms.