Helical is building the AI-native lab for biology; replacing slow, costly wet lab experimentation with scalable, virtual discovery. Our platform is already deployed with leading global pharma, enabling teams to run millions of experiments in days, not years.
We have product-market traction. Now we’re scaling and looking for someone to build and lead that journey.
We’re hiring a Head of Sales to own new business and build Helical’s commercial function from the ground up.
This is a player-coach role. You’ll be responsible for closing high-value deals yourself, while also shaping how we go to market; defining the playbook, building pipeline, and laying the foundations for a high-performing commercial team.
This is not a “manage and inherit” role. This is build, sell, and scale.
Requirements
Win New Business
Land new logos across top pharma and large biotech
Own the full sales cycle from prospecting to close
Navigate complex, multi-stakeholder deals with scientific buyers
Turn initial deals into long-term, multi-program partnerships
Build the GTM Engine
Define and execute the go-to-market strategy
Build repeatable pipeline, qualification, and forecasting processes
Implement AI-first sales workflows across prospecting and pipeline management
Hire, mentor, and scale the early commercial team
Drive Strategic Growth
Develop partnerships across pharma, tech, and research ecosystems
Expand Helical’s footprint through high-value relationships and collaborations
Be the Market Face
Represent Helical with credibility at key industry events and conferences
Build relationships with decision-makers in discovery, computational biology, and AI
Who You Are
Proven track record of closing complex enterprise deals and winning new logos
Experience building GTM and sales functions from scratch (early-stage environments)
Strong ability to sell into technical and scientific stakeholders
Comfortable operating in ambiguity and owning outcomes end-to-end
AI-first mindset—you leverage AI across your workflows to drive better results
Deep interest in how AI is transforming drug discovery
Benefits
Proven product already in use with top pharma
Opportunity to shape a category-defining company at an inflection point
High ownership, direct impact, and close collaboration with founders
Clear trajectory to CRO / full commercial leadership