Biologist

Candidates must be familiar with multiple scRNA-seq/snRNA-seq platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences). They are focused on the discovery and early phase clinical development of biologic, small molecule, oligonucleotide, and cell therapies for treatment of diabetes, obesity, cardiovascular disease, and associated metabolic disorders.

Job Title: Biologist
Location: Boston, MA
Work Model: Onsite
Hours: M-F 8am-5pm
Compensation: $48.70 - $57.25/hr
Type: 6-month contract, Potential for extension or conversion to permanent

Overview
Come join the Cardiometabolic Research (CMR) team at our client! They are focused on the discovery and early phase clinical development of biologic, small molecule, oligonucleotide, and cell therapies for treatment of diabetes, obesity, cardiovascular disease, and associated metabolic disorders. The Data Science team within CMR is seeking someone with wide-ranging experience in next-generation sequencing library preparation to help achieve their research goals. The successful candidate will be responsible for RNA-seq, scRNA-seq, snRNA-seq, and other types of -seq library preparations for all CMR groups. This will be a cross-therapeutic area role encompassing opportunities to impact science in the Boston team.

Responsibilities

• Conduct experiments to identify and validate drug targets.
• Support assay design, optimization, validation, and data analyses.
• Design and execute molecular and cell biology experiments.
• Troubleshoot and analyze complex data in support of drug discovery projects.
• Presentation of results and conclusions both orally and written.

Qualifications
Required

• B.S. and/or M.S. in biological or biochemical sciences (or a related field) with 3-5 years of laboratory research experience.
• Molecular biology mastery of nucleic acid extraction and purification, quantification, NGS library preparation/QC, and qPCR.
• Strong background in NGS technologies and their applications, including quantification, sequencing, and data QC (preferably Illumina). Direct experience with RNA-seq (bulk) and amplicon-seq.
• Direct experience with single-cell and single-nucleus RNA-seq library preparation is required. Candidates must be familiar with multiple scRNA-seq/snRNA-seq platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences).

Preferred

• Familiarity with CRISPR-based gene editing and high-throughput screening is a plus.
• Experience with automation is a plus (Mantis, Integra systems, Liquid Handlers, SPTLabtech Firefly, Tecan, etc).
• Strong organizational, time management, and communication skills.
• Experience with documentation in electronic notebook software.

System One, and its subsidiaries including Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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Ref: #558-Scientific