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Assistant Scientist - AI-Enabled Immune Digital Twin Workflows, Data Assimilation, and Ensemble Updating

Indiana University

  • Bloomington, IN
  • 1 day ago

    Highlights

    60% Digital Twin Workflows & Data Assimilation: Develop Python workflows for short-horizon forecasting and patient-specific rebasing; implement data-assimilation methods (Kalman/Bayesian updating); design anomaly detection and missing-information inference logic. You will implement patient-specific forecasting and rebasing pipelines, design anomaly-detection and residual-monitoring logic, infer unobserved state parameters, manage complex model ensemble interfaces, and coordinate computational infrastructure with national consortium collaborators.

    Numbers & Facts

    LocationBloomington, IN

    Description

    Posting Details

    Position Details

    Title Assistant Scientist - AI-Enabled Immune Digital Twin Workflows, Data Assimilation, and Ensemble Updating Appointment Status Non-Tenure Track Department IU Bloomington Intelligent Systems Engineering Location Bloomington Position Summary

    Your primary duties will be to build reproducible, testable, sequential data-assimilating digital twin workflows under the direction of Dr. James A. Glazier. You will implement patient-specific forecasting and rebasing pipelines, design anomaly-detection and residual-monitoring logic, infer unobserved state parameters, manage complex model ensemble interfaces, and coordinate computational infrastructure with national consortium collaborators.

    60% Digital Twin Workflows & Data Assimilation: Develop Python workflows for short-horizon forecasting and patient-specific rebasing; implement data-assimilation methods (Kalman/Bayesian updating); design anomaly detection and missing-information inference logic.

    40% Software Engineering & Integration: Build reproducible computational packages(CI/CD, containers, testing); manage ensemble interfaces; integrate workflows with external consortium platforms (Vivarium, QSP); write technical publications.

    Basic Qualifications

    Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline.

    Programming proficiency in Python, Julia, R, or MATLAB; background in mechanistic modeling (ODE/dynamical systems, QSP, or agent-based); familiarity with inflammation, cytokine signaling, sepsis, or critical care biology.

    One year of successful postdoctoral research experience.

    Department Contact for Questions

    Please contact Professor James Glazier at glazier@iu.edu with questions regarding the position.

    Additional Qualifications Salary and Rank 100,000/Assistant Scientist Special Instructions For Best Consideration Date 11/02/2026 Expected Start Date Posting Number IU-101733-2026

    Supplemental Questions

    Required fields are indicated with an asterisk (*).

      • Have you previously been employed with IU?
    • Yes
    • No

    Applicant Documents

    Required Documents

    • Curriculum Vitae
    • Letter of Application
    • List Of References

    Optional Documents

    • Letter of Reference 1
    • Letter of Reference 2
    • Letter of Reference 3

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