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Assistant Scientist - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model

Indiana University

  • Bloomington, IN
  • 1 day ago

    Highlights

    40% Consortium Deliverables & Research: Prepare test cases, model packages, and model cards; write research papers; present findings; collaborate with national consortium partners in systems biology and clinical data science. You will map clinical biomarkers to model states, define biological scoring criteria for digital twin ensembles, collaborate with national consortium partners, write technical publications, and prepare milestone-ready contract deliverables.

    Numbers & Facts

    LocationBloomington, IN

    Description

    Posting Details

    Position Details

    Title Assistant Scientist - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model Appointment Status Non-Tenure Track Department IU Bloomington Intelligent Systems Engineering Location Bloomington Position Summary

    AI-Enabled Immune Digital Twin & Organ damage Mechanistic Model Scientist: Assistant Scientist; Biocomplexity Institute at Indiana University Bloomington (PI: Dr. James A. Glazier)

    Your primary duties will be to develop biologically meaningful, interpretable model components linking immune-state dynamics to organ-damage risk (lung, kidney, liver) in critical illness under the direction of Dr. James A. Glazier. You will map clinical biomarkers to model states, define biological scoring criteria for digital twin ensembles, collaborate with national consortium partners, write technical publications, and prepare milestone-ready contract deliverables.

    60% Dynamic Immune & Organ Modeling: Develop fast, interpretable

    ODE/network/mechanistic model modules linking immune dysfunction to organ injury; map clinical time-series and biomarkers to model states; formulate biological plausibility and scoring criteria.

    40% Consortium Deliverables & Research: Prepare test cases, model packages, and model cards; write research papers; present findings; collaborate with national consortium partners in systems biology and clinical data science.

    Basic Qualifications

    Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline.

    Programming proficiency in Python, Julia, R, or MATLAB; background in mechanistic modeling (ODE/dynamical systems, QSP, or agent-based); familiarity with inflammation, cytokine signaling, sepsis, or critical care biology.

    One year of successful postdoctoral research experience.

    Department Contact for Questions

    Please contact Professor James Glazier at glazier@iu.edu.

    Additional Qualifications Salary and Rank 100,000/Assistant Scientist Special Instructions For Best Consideration Date 11/02/2026 Expected Start Date Posting Number IU-101731-2026

    Supplemental Questions

    Required fields are indicated with an asterisk (*).

      • Have you previously been employed with IU?
    • Yes
    • No

    Applicant Documents

    Required Documents

    • Curriculum Vitae
    • Letter of Application
    • List Of References

    Optional Documents

    • Letter of Reference 1
    • Letter of Reference 2
    • Letter of Reference 3

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