UNIV - Postdoctoral Fellow - Department of Biochemistry

Job Description Summary

The department of Biochemistry & Molecular Biology at MUSC has an immediate opening for a highly motivated and collegial Postdoctoral Fellow in the laboratory of Dr. Noel Warfel. The Warfel lab focuses on the role of hypoxia and reoxygenation in tumor metastasis and drug resistance. The Successful candidate will perform integrated multi-omics statistical and bioinformatics analysis to understand how temporal hypoxia alters cancer cell resistance to therapy and related biological processes. The lab is also invested in drug development and testing in prostate cancer and other solid tumors. The candidates will work to integrate multiomics data sets including RNA-seq, lipidomics, and phospho-proteomics.

Entity: Medical University of South Carolina (MUSC) Univ: Worker Type: Employee Worker Sub-Type: Regular Cost Center: CC001336 HCC Recruitment & Retention Pay Rate Type: Salary Pay Grade: University-00 Pay Range: 0.00 - 0.00 - 0.00 Scheduled Weekly Hours: 40 Work Shift: [Not Specified]

Job Description

Job Purpose The position will entail a combination of unbiased discovery and hypothesis-driven research to derive causal relationships between hypoxia-driven pathways contributing to cancer drug resistance. The candidate will be responsible for the generation and analysis of large-scale datasets and relating those findings to generate testable models for mechanistic investigations. Key responsibilities will be to integrate multi-omics to uncover mechanisms of therapeutic resistance and identify biological vulnerabilities related to changing oxygen in tumors. The candidate will work with the PI to implement a career development plan and participate in various career advancement opportunities. The candidate will also mentor undergraduate, graduate students, and postdoctoral fellows in the Lab.

Additional Knowledge, Skills & Abilities (Preferred)

• Prior experience with multi-omics data analysis and publications in bioinformatics are preferred.
• Must have the ability to think creatively and work independently as well as part of the team.
• Must have strong organizational skills, verbal and written communication skills, and interpersonal skills.

Job Duties

• 30% - Analyze and interpret complex transcriptomic, proteomic, and lipidomic datasets/molecular datasets to identify novel biology related to tumor progression and metastasis.
• 30% - Collaborate with graduate students and scientists at MUSC to identify actionable targets for mechanistic evaluation of tumor biology.
• 15% - Work with the PI to create a career development plan and participate in various career advancement opportunities.
• 15% - Interact and coordinate efforts with undergraduate, graduate students, and postdoctoral fellows in the lab.
• 10% - Stay updated on the latest advancements in cancer biology, bioinformatics, and genomics research and present findings to internal teams and external stakeholders while also publishing research outcomes and presenting at conferences.

Additional Job Description: Physical Requirements Note: The following descriptions are applicable to this section.

• Continuous: 6-8 hours per shift
• Frequent: 2-6 hours per shift
• Infrequent: 0-2 hours per shift

Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform pinching operations. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs. unassisted. (Continuous) Ability to lift objects up to 15 lbs. from floor level to height of 72 inches unassisted. (Frequent) Ability to lower objects up to 15 lbs. from height of 72 inches to floor level unassisted. (Frequent) Ability to push/pull objects up to 15 lbs. unassisted. (Frequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Infrequent) Ability to maintain 20/40 vision corrected. (Frequent) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects/depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically by medical personnel for respirator use initially and annually. (Continuous) Ability to work alone in isolated areas such as darkrooms. (Frequent)

Additional New Requirements

• Ability to obtain and maintain a valid drivers license.
• Computer literacy.
• Ability to work rotating shifts as required.
• Ability to work overtime as required.
• Ability to learn and use new processes, tools, and equipment as required.

If you like working with energetic, enthusiastic individuals, you will enjoy your career with us.

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit, and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program please click here: http://www.uscis.gov/e-verifyemployees