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Senior Manager, Clinical Data Management

Connexion Systems + Engineering

Remote, MA(remote)

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JOB DETAILS
SALARY
$110–$125 Per Hour
SKILLS
Acceptance Testing, Audit Metrics, Budgeting, Case Report Form (CRF), Clinical Data, Clinical Data Collection, Clinical Data Management, Clinical Practices/Protocols, Clinical Research, Clinical Trial, Compensation and Benefits, Contract Research Organization (CRO), Cross-Functional, Data Cleaning, Data Collection, Data Management, Data Processing, Database Analysis, Electronic Data Capture (EDC), Financial Management, GCP (Good Clinical Practices), GxP, ICH Regulations, Industry Standards, Laboratory, Medical Coding, Medical Research, Medical Writing, Mentoring, Oncology, Operations Research, People Management, Quality Control, Reconciliation, Risk Analysis, Standard Operating Procedures (SOP), System Validation, Systems Engineering, Training Data Sets
LOCATION
Remote, MA
POSTED
24 days ago
Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.

Title: Senior Manager, Clinical Data Management
Hiring Organization: Connexion Systems & Engineering

Compensation, Benefits, and Employment Type
  • Duration: 6 month contract
  • Pay rate: $110-$125/hr
  • Job Location: Remote
  • Schedule: M-F, flexibility required to accommodate global team members
  • Job#: bh18341

Description:
We are seeking a highly experienced Senior Manager, Clinical Data Management to lead multiple high-volume, complex clinical studies. This role requires deep expertise in Oncology trials, Medidata Rave, and ideally Elluminate. The Senior Manager will provide strategic oversight, hands-on execution, and mentorship while collaborating cross-functionally with internal teams, external vendors, and CRO partners.

This is a fully remote position supporting global teams and requires someone who can start immediately.
Key Responsibilities
  • Lead all clinical data management activities across assigned studies with full functional, administrative, and financial oversight.
  • Identify potential out-of-scope activities early and collaborate on contract modifications while maintaining budget alignment.
  • Mentor and guide junior staff and study teams to achieve high-quality, compliant deliverables aligned with ICH/GCP.
  • Proactively identify and resolve operational challenges based on metrics, audit findings, and team input.
  • Assess risk throughout study lifecycles and implement mitigation strategies.
  • Execute and oversee clinical data management tasks, including data processing, QC, enrollment tracking, eCRF review, and query management.
  • Collaborate with CROs, vendors, CDM, and Clinical teams to develop and review CRFs, annotations, and other data collection tools.
  • Contribute to the creation and refinement of CDM SOPs and Work Instructions.
  • Review and provide guidance on DMPs, DVS/edit checks, SAE reconciliation plans, and data cleaning strategies.
  • Partner with CROs to support data cleaning, interim analyses, database lock, and ad hoc requests.
  • Liaise with external labs and vendors on timelines and deliverables.
  • Develop data transfer agreements and technical specifications.
  • Review and validate EDC systems, including screens, edit checks, code lists, UAT outputs, and database structures.
  • Provide input on protocols, SAPs, and clinical study reports.
  • Collaborate cross-functionally with Clinical Operations, Research, Medical Monitoring, Medical Writing, and other teams to ensure accuracy and efficiency in data collection.
  • Apply industry-standard conventions and processes for medical coding.
  • Oversee study timelines, ensuring milestones and data management standards are met with high quality.
  • Perform other related duties as needed.
Required Qualifications
  • 10–12 years of experience in Clinical Data Management.
  • Strong background in Oncology clinical trials.
  • Extensive experience with Medidata Rave.
  • Experience with Elluminate preferred.
  • Proven success overseeing multiple complex studies and mentoring CDM teams.
  • Strong understanding of ICH/GCP, GxP principles, and global clinical data standards.
 
Please use the apply button to submit your resume for consideration.  A Connexion Representative will contact you shortly.

You may also send your resume and cover letter via email to the recruiter listed below. You MUST include the Job# and Job Title in your subject line.

If you are active in a job search but this job is not for you, please reach out to 

jobpostings@csetalent.com

. We would be glad to help you find the perfect job!

About the Company

C

Connexion Systems + Engineering

Connexion is an award-winning professional staffing firm that strives to be the unrivaled staffing solution for job seekers by expertly connecting talent with opportunity.  Over the last 20 years Connexion has built the most admired team of staffing experts in the industry.  We give back, change lives and offer unconditional support to the candidates we represent.

Put Connexion's 20 years of experience to work for you! Our professionals have unrivaled relationships and contacts with the hiring managers, human resources team and decision makers at the most desirable companies to work for.

Don't let your resume get lost in an inbox, Connexion's recruiting team will advocate on your behalf to get you the job you want

COMPANY SIZE
500 to 999 employees
INDUSTRY
Staffing/Employment Agencies
FOUNDED
1999
WEBSITE
https://www.csetalent.com/