Senior Clinical Bioinformatician, Molecular Medical Genetics Lab, Winston Campus

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Senior Clinical Bioinformatician, Molecular Medical Genetics Lab, Winston Campus

Winston Salem, NC, United States

Job ID: R237233

Shift: 1st

Job Type: Regular

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Department:

60939 Wake Forest Baptist Medical Center - Lab: Molecular Medical Genetics

Status:

Full time

Benefits Eligible:

Yes

Hours Per Week:

40

Schedule Details/Additional Information:

Monday thru Friday

8AM - 5PM

possible occasional extra hours as needed

Pay Range

$44.15 - $66.25

Position Highlights:

• Full-Time; 40 hours/week

• Monday thru Friday, 8AM - 5PM, possible occasional extra hours as needed

• Winston Campus

MAJOR RESPONSIBILITIES

• Lead project management efforts, ensuring timely completion of goals and projects in alignment with strategic plans, and identify necessary resources for successful delivery.
• Conduct regular audits of bioinformatics processes to identify areas for improvement and ensure compliance with best practices and regulatory requirements.
• Implement and manage bioinformatics methodologies and pipelines for somatic and germline targeted genes sequencing, exhibiting good code and development practice.
• Analyze and interpret NGS data from various sequencing platforms (e.g., Illumina, Ion Torrent) for clinical applications such as hereditary disease diagnostics, cancer genomics, and solid tumor mutation detection.
• Hands-on design, develop, and optimize bioinformatics pipelines for tasks like variant calling, copy number variation (CNV) detection, structural variant analysis, and gene expression profiling.
• Work closely with clinical laboratory staff, pathologists, directors, and researchers to translate bioinformatics analyses into actionable clinical insights. Communicate complex bioinformatics concepts and results to non-technical stakeholders in a clear and effective manner.
• Assess data analysis workflows to identify opportunities for automation of analysis, reporting, and quality control (QC). Implement improvements in collaboration with laboratory leadership.
• Ensure all bioinformatics workflows and analyses comply with clinical laboratory regulations and standards (e.g., CLIA, CAP). Lead the validation and verification of bioinformatic systems, including modifications, upgrades, and other changes; develop and maintain documentation for bioinformatics processes.
• Develop and implement bioinformatics policies and practices that adhere to CLIA, CAP, CDC, OSHA, AABB, and FDA guidelines. Oversee CAP bioinformatics surveys and ensure compliance with CAP inspections. Monitor regulatory changes and update policies accordingly.
• Ensure the implementation of effective quality assurance and quality control programs, integrating with related committees and processes to maintain high standards.

Education/Experience:

• Ph.D. in Bioinformatics, Statistics, Computer Science, data science or a related field and 3+ years of bioinformatics experience, OR
• Master's degree with 5+ years of experience, OR
• Bachelor's degree with 8+ years of experience.
• Experience with Linux-based or cloud computing environments.
• Proficiency in Python, R for developing somatic and germline analysis pipelines, with experience managing the codebase using Git.
• Proven experience in NGS data analysis, variant detection, and annotation.

KNOLWEDGE, SKILLS AND ABILITIES REQUIRED

• Familiar with the basic of genomics, genetics or molecular and cell biology.
• Proficiency in Python, R, Bash, or similar programming/scripting languages.
• Experience with high-performance computing (HPC) and cloud platforms is preferred.
• Ability to write custom code for constructing analysis pipelines and manipulating sequence data.
• Familiarity with cancer genomics, liquid biopsy, or hereditary disease testing preferred.
• Experience with machine learning applications in bioinformatics preferred.
• Demonstrated organizational ability, attention to detail, and accuracy.
• Effective written and verbal communication skills and ability to build rapport and relate to all people.
• Ability to work in a fast-paced environment and to handle multiple tasks simultaneously.
• Excel with working independently, troubleshooting problems, and providing solutions.
• Ability to speak effectively and present material to be understood by a diverse group of individuals.
• Maintains patient confidentiality in and out of the workplace.

DISCLAIMER

All responsibilities and requirements are subject to possible modification to reasonably accommodate individuals with disabilities.

This job description in no way states or implies that these are the only responsibilities to be performed by an employee occupying this job or position. Employees must follow any other job-related instructions and perform any other job-related duties requested by their leaders.

Our Commitment to You:

Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more - so you can live fully at and away from work, including:

Compensation

• Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training

• Premium pay such as shift, on call, and more based on a teammate's job

• Incentive pay for select positions

• Opportunity for annual increases based on performance

Benefits and more

• Paid Time Off programs

• Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability

• Flexible Spending Accounts for eligible health care and dependent care expenses

• Family benefits such as adoption assistance and paid parental leave

• Defined contribution retirement plans with employer match and other financial wellness programs

• Educational Assistance Program

Note: Eligibility for programs listed above may depend on your FTE or status (e.g., full-time, part-time, per diem, temporary, etc.); please ask a Recruiter for more information during an interview.

About Advocate Health

Advocate Health is the third-largest nonprofit, integrated health system in the United States, created from the combination of Advocate Aurora Health and Atrium Health. Providing care under the names Advocate Health Care in Illinois; Atrium Health in the Carolinas, Georgia and Alabama; and Aurora Health Care in Wisconsin, Advocate Health is a national leader in clinical innovation, health outcomes, consumer experience and value-based care. Headquartered in Charlotte, North Carolina, Advocate Health services nearly 6 million patients and is engaged in hundreds of clinical trials and research studies, with Wake Forest University School of Medicine serving as the academic core of the enterprise. It is nationally recognized for its expertise in cardiology, neurosciences, oncology, pediatrics and rehabilitation, as well as organ transplants, burn treatments and specialized musculoskeletal programs. Advocate Health employs 155,000 teammates across 69 hospitals and over 1,000 care locations, and offers one of the nation's largest graduate medical education programs with over 2,000 residents and fellows across more than 200 programs. Committed to providing equitable care for all, Advocate Health provides more than $6 billion in annual community benefits.

Provide leadership and expertise in bioinformatics methodology development, implement and maintain production pipelines to support clinical diagnostics efforts. This role will lead and manage bioinformatics projects, collaborate with teammates, wet-lab scientist, clinician, and IT teams to analyze and interpret genomics data, ensuring high-quality and compliant clinical reporting. Strong background in Next-Generation Sequencing (NGS) data analysis.

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