Research Triangle Park, NC
Description
Kriya is a biopharmaceutical company whose mission is to develop life-changing gene therapies for diseases affecting millions of patients around the world.
We leverage our proprietary computational engine, in-house manufacturing infrastructure, and integrated design platform to engineer technologies and therapeutics with the potential to transform the treatment of a broad universe of diseases of high unmet need, with a focus on metabolic disorders, neurology, and ophthalmology.
We are proud to have been named Triangle Business Journal’s Life Sciences 2024 “Best Private Company to Work For,” recognized by Forbes as one of “America’s Best Startup Employers of 2024,” and honored as one of BioSpace’s “2025 Best Places to Work.”
Role Overview
The Scientist III, Analytical Development will uses their knowledge and experience in analytical development of complex therapeutic products to develop methods to evaluate the identity, quantity, purity, and/or potency of AAV products. They serve as Subject Matter Expert (SME) and primary AD representative for one or more analytical technologies for AAV products.
Key Responsibilities
- Develop chromatographic, electrophoretic and ELISA-based analytical methods for identity, quantitation and purity analysis of AAV in-process, drug substance and drug product.
- Collaborate with other scientists to identify areas of improvement.
- Review and approve ELN entries for other group members.
- Execute test methods in support of process development and development vector characterization.
- Support Quality Control with qualification/validation of analytical test methods and identify needs for release testing.
- Evaluate emerging technologies for characterization of AAV and process intermediates and implement as needed.
- Author documents in support of manufacturing activities.
- Collaborate with other scientists and routinely present data.
- Perform other duties as necessary.
Experience & Skills and Work Environment
Experience & Skills
- BS or equivalent in Science, Biotechnology, Engineering or other related field with 10+ years of industry experience.
- Master’s degree with 6+ years of industry experience.
- PhD with 4+ years of industry experience.
- Experience with analytical techniques including Chromatography, ELISA, Capillary Electrophoresis strongly preferred.
- In-depth experience of the development, qualification, and implementation of analytical methods for the characterization and release testing of AAV vectors or biologic products in an industry setting strongly preferred.
- Relevant AAV gene therapy experience in leading analytical development is preferred.
- Previous experience with development of analytical methods supporting late-stage clinical manufacturing is a plus.
- Experience with characterization and release testing of viral vector-based systems, plasmid DNA, or RNA products is a plus.
- Sound understanding and demonstrated application of statistical methods/tools.
- Strong verbal, written, and interpersonal communication skills.
- Self-motivated, organized, capable of working independently and in a collaborative environment.
- Exercise of discretion and independent judgment.
- Ability and desire to work in a fast paced, startup environment.
- An ability to build effective relationships and work cross-functionally to deliver results and meet business objectives.
Work Environment
- Primarily a desk setting but may include laboratory work.
- May involve standing, sitting, and using laboratory equipment for extended periods.
- Must have flexible work hours, and be willing to work outside of normal, schedule hours; as necessary.
Life at Kriya
Discover True Collaborative Teamwork
We have an ambitious set of goals, but our confidence – and our inspiration – stems from our people. From California to North Carolina, our teammates bring a spirit of Collaboration, Leadership, and Innovation to their work every day.
We’re always looking for teammates with the drive and energy to help us grow. If you want to be a part of a company with an entrepreneurial culture, a bold vision, and a meaningful purpose, join us.
Rewards & Benefits
- Time Off & Work-Life Balance: Flexible Time Off Paid Parental & Medical Leave Paid Company Holidays
- Health & Wellness: Fertility & Family Building Benefits Medical, Dental, and Vision Insurance Employee Assistance Program (EAP) Life Insurance Short- and Long-Term Disability Coverage
- Financial Security:Equity 401(k) with Company Match Identity Theft Protection
- And More!