Analysis Skills, Biology, Cell Biology, Cell Cultures, Clinical Medicine, Clinical Research, Communication Skills, Cross-Functional, DNA, DNA Sequencing, Data Analysis, Data Collection, Detail Oriented, Disease, Documentation, Equipment Maintenance/Repair, Genomics, Hospital, International Health, Laboratory, Laboratory Equipment, Laboratory Operations, Laboratory Techniques, Medicine, Molecular Biology, Neurology, Neuroscience, Next Generation Sequencing (NGS), Nonprofit, Oncology, Patient Care, People Management, Polymerase Chain Reaction (PCR), Presentation/Verbal Skills, Problem Solving Skills, Real-time PCR (qPCR), Record Keeping, Regulations, Research Laboratory, Team Player, Technical Research, Time Management, Translational Research, Willing to Travel, Writing Skills
Job Summary and Responsibilities
As a Research Tech, you will perform standard laboratory procedures with some independence, under the general supervision of a PI or Research Technician. Your contributions are vital for efficient lab operations.
Every day you will execute experimental protocols, collect/record data, and maintain lab equipment. You may also perform complex procedures and provide guidance to students.
To be successful in this role, you will possess a strong foundation in lab techniques, meticulous attention to detail, and work effectively independently and collaboratively. Reliability, safety adherence, and a willingness to learn are key. Other primary responsibilities include:
- Receive process and manage biospecimens-including tumor tissue cerebrospinal fluid (CSF) and blood-in compliance with CLIA-regulated protocols
- Isolate cell-free DNA from CSF and extract genomic DNA from tumor tissue and peripheral blood
- Isolate circulating cells from CSF and perform tissue dissociation for downstream applications
- Prepare single-cell RNA sequencing libraries using the 10x Genomics platform from tumor and CSF-derived cells
- Generate DNA sequencing libraries from tumor tissue blood and cell-free DNA
- Maintain rigorous accurate documentation of experimental workflows in accordance with established protocols and regulatory standards
- Contribute to a collaborative research environment through participation in lab meetings seminars and journal clubs
- Keeps accurate records of studies conducted with minimal supervision.
- Performs basic data analysis and processing as required by senior laboratory personnel.
- Creates, maintains, and updates lab's internal procedure manuals.
The Ivy Brain Tumor Center is a pioneering non-profit clinical research program dedicated to developing transformative therapies for patients with aggressive brain tumors. As a global leader in early-phase neuro-oncology trials the Center hosts the largest portfolio of Phase 0 studies for brain tumors worldwide. Our multidisciplinary team integrates clinical care translational science and precision medicine to accelerate the identification and development of first-in-class therapies.
We are seeking a highly motivated Research Tech II to join our translational neuro-oncology research team. This role is ideal for an individual with strong laboratory experience who is capable of independently executing complex experimental workflows. The successful candidate will play a key role in advancing innovative liquid biopsy platforms to study pharmacogenomic response tumor evolution and disease progression.
Job Requirements
Required
- Bachelor's degree in biological sciences or a related field
- Two (2) years prior experience in ar research, clinical, or other scientific environment
- Prior laboratory research experience with demonstrated proficiency in cell culture molecular biology techniques (e.g. PCR qPCR) and/or sequencing library preparation
- Strong analytical and problem-solving skills with the ability to learn and execute new techniques independently
- Excellent attention to detail organization and time management
- Strong written and verbal communication skills
Preferred
- Four (4) years of prior experience in a research, clinical, or other scientific environment
- Background in cell biology neuroscience or oncology
- Familiarity with CLIA-regulated workflows and liquid biopsy methodologies
- Experience with single-cell RNA sequencing and next-generation sequencing platforms
- Additional Information: Two to three letters of recommendation may be requested
Where You'll Work
Hello Humankindness: Join a Legacy of Healing at Saint Joseph's Hospital and Medical Center (SJHMC)
Ready to make a real difference? Join SJHMC in Phoenix AZ., a 571-bed nonprofit founded by the Sisters of Mercy over 125 years ago. We're more than a hospital; we're a global destination for life-changing care, embracing patients with humankindness.
Here, your calling will flourish. We're not just a workplace; we're a community dedicated to a mission of service.
Leaders in Specialized Care:
- Barrow Neurological Institute (BNI): A world-renowned center for groundbreaking neurological research and innovative treatments.
- Norton Thoracic Institute (NTI): A national leader in advanced thoracic care with pioneering surgical techniques.
- Level I Trauma Center: One of Arizona's busiest ERs, providing immediate, comprehensive care for critically injured patients 24/7.
Why SJHMC?
- Culture of Excellence & Well-being: We care for our people, fostering professional and personal growth.
- Community & Collaboration: Be part of a network committed to global health and well-being.
- Join a Legacy, Shape a Future: Over 20% of our patients travel internationally for our specialized care.
This is an invitation to join a family of dedicated professionals at the forefront of medical innovation, united by the power of humankindness.