Research Associate, In Vivo

Frontier Medicines is seeking a highly motivated Research Associate II to join the In Vivo Phamacology group. This role combines hands-on in vivo pharmacology work in our South San Francisco vivarium with translational research responsibilities, The successful candidate will work as part of a multidisciplinary team in a fast-paced drug-discovery environment, contributing to both internal preclinical studies and translational medicine activities.

What will you be doing?

In Vivo Pharmacology:

• Execute in vivo experiments to evaluate the efficacy and PKPDTE relationship of novel compounds across multiple programs.
• Conduct murine-based tumor model studies, including animal handling, dosing via multiple routes, and health monitoring
• Perform mouse necropsies, tissue harvest, blood collection, and sample processing for downstream analysis
• Formulate and prepare test substances for in vivo administration
• Maintain sample inventory and coordinate sample shipment to designated internal and external teams
• Ensure animal welfare and maintain compliance with IACUC, GLP, and non-GLP policies through detailed electronic laboratory notebook documenting
• Maintain a clear, detailed electronic laboratory notebook to document all experiments and finding
• Knowledge in cell culture

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Translational Research:

• Manage mouse tumor model activities at CROs and through external collaborations.
• Design, coordinate, and conduct in vivo mouse tumor model studies in collaboration with the Translational Medicine team.
• Manage and support in vivo studies across multiple programs concurrently.
• Perform data analysis and prepare presentations for internal and external audiences.
• Effectively communicate with colleagues, collaborators, and stakeholders; engage in the science beyond the experimental objective.