Postdoctoral Researchers - bench and dry lab scientists in the field of lipoprotein metabolism and the role of lipids in cardiometabolic traits and diseases (including atherosclerosis and metabolic dysfunction-associated steatotic liver disease or M

University of Pennsylvania

Philadelphia, PA

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JOB DETAILS

SKILLS

Bash Scripting, Bioinformatics, Biology, Biomarkers, Biomedicine, Biostatistics, Cardiovascular Disease, Communication Skills, Computer Science, Data Management, Disease, Genetics, Genomics, Genotyping, High Throughput, Laboratory, Presentation/Verbal Skills, Proteomics, Python Programming/Scripting Language, R Programming Language, SQL (Structured Query Language), Statistics, Stem Cells, Writing Skills

LOCATION

Philadelphia, PA

POSTED

1 day ago

Faculty Mentor: Daniel J. Rader MD

Hiring Department: Medicine - Division of Translational Medicine and Human Genetics

Funding Sources: NIH and AHA grants

Number of Positions: 2

U.S. citizens and foreign nationals may apply.

Rader lab website: https://www.med.upenn.edu/raderlab/

Applications are invited for postdoctoral positions in the laboratory of Dr. Daniel J. Rader, Departments of Medicine and Genetics at the Perelman School of Medicine (PSOM) of the University of Pennsylvania. The Rader lab is a multidisciplinary research environment focused on leveraging human gene discovery to elucidate the biology and molecular physiology of genes and pathways that influence plasma lipoprotein metabolism as well as the role of lipids in cardiometabolic traits and diseases (including atherosclerosis and metabolic dysfunction-associated steatotic liver disease or MASLD) and neurodegeneration/Alzheimer’s disease. The lab integrates computational genomics, fundamental molecular investigation in cell and animal model systems, and targeted deep phenotyping in human subjects to establish molecular mechanisms, clinical relevance and accelerate translation of research insights to potential treatment of human cardiometabolic disorders. Approaches to this work incorporate 1) computational multi-omics to identify genes and pathways of interest; 2) human induced pluripotent stem cell (iPSC)-derived cell types to examine impact on hallmarks or biomarkers of phenotype and/or disease; 3) mouse model systems including germline and somatic gene manipulation; 4) use of natural genetic variants to elucidate protein structure-function relationships, and 5) recall-by-genotype studies in humans for deep phenotyping to inform genotype-phenotype relationships. We particularly encourage inquiries from 1) bench scientists with some background in lipid metabolism and 2) dry lab scientists with experience in bioinformatics and high-throughput genomics, metabolomics and/or proteomics technologies.

Bench scientists: PhD in a biological science and a strong record of academic productivity are required; excellent written and verbal communication skills are also required. Individuals should be able to demonstrate an ability to successfully complete projects independently. Applicants with experience in genetics/genomics, biochemistry, cell biology, or physiology, and/or cell and mouse models, are encouraged to apply. We are particularly interested in bench scientists with some background in lipid metabolism.

Dry lab scientists: Ph.D. degree in Biostatistics, Computer Science, Bioinformatics, or other biomedical domain required. A strong record of academic productivity, excellent written and verbal communication skills are also required. Individuals should be able to demonstrate an ability to successfully complete projects independently. Additionally, the following skills are desirable: fluency in statistical and data management computer languages such as R, Python, Bash, and SQL. We are particularly interested in individuals with experience in bioinformatics and high-throughput genomics, metabolomics and/or proteomics technologies.

To apply, please submit the following through Interfolio:

1. Brief statement of your research experience and interests detailing your qualifications for this position

2. Curriculum Vitae

3. Name and contact information of three references.

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.

About the Company

University of Pennsylvania

Penn's beautiful urban campus provides easy access to a range of educational, cultural, and recreational activities. We offer excellent healthcare and tuition benefits for you and your family, as well as generous retirement benefits, professional development opportunities and flexible work options. Penn is a diverse, multicultural learning community at the cutting edge of research and information technology. Click here to read more about why we're a Best Employer. Not only does Penn offer a unique environment within the city of Philadelphia to work, we also provide a wide array of employee benefits. From a competitive retirement program and comprehensive health care options to health promotion and wellness services and tuition assistance, there's a wealth of opportunities and resources available to you at Penn.

Penn is frequently cited as an outstanding employer:

Recipient of the 2010 Terri Lynne Lokoff Child Care Foundation Corporate Leadership Award for commitment to supporting worklife balance programs.
Selected as a recipient of the 2010 Healthy Workplace Award by the Philadelphia Business Journal and presenting sponsor UnitedHealthcare
Recognized as a 2010 Top Workplace by The Philadelphia Inquirer/Daily News.
Recipient of the 2009 Vision Award for commitment to workforce diversity and economic inclusion.
Selected for Computerworld's 100 Best Places to Work in IT six years in a row!
Recognized by the Delaware Valley Association for the Education of Young Children as a 2006 Best Employer for Working Parents
Named a Best Place to Work in the November 2007 issue of Philadelphia Magazine.
Designated a Best Workplace for Commuters by the National Center for Transit Research

COMPANY SIZE

100 to 499 employees

INDUSTRY

Advertising and PR Services

FOUNDED

1990

WEBSITE

http://www.cmimedia.com/