Post-Doctorate Research Associate - Lipidomics and Biomarker Development

Pacific Northwest National Laboratory

Richland, WA

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JOB DETAILS

SALARY

SKILLS

Adjudication, Analysis Skills, Analytical Chemistry, Artificial Intelligence (AI), Assays, Background Investigation, Biochemistry, Bioenergy, Bioinformatics, Biology, Biomarkers, Biomedical Software, Budgeting, Clinical Information Systems, Communication Skills, Conferences, Cross-Functional, Data Sets, Diabetes, Earth Sciences, Ecosystems, Environmental Sciences, Equal Employment Opportunity (EEO), Genomics, Government, Homeland Security, Hubs, Human Health, Instrumentation, Leadership, Liquid Chromatography, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry, Molecular Analysis, National Institutes of Health (NIH), Physical Science, Plasma, Presentation/Verbal Skills, Problem Solving Skills, Proposal Development, Publications, Recreation, Research Skills, Sample/Specimen Processing, Scientific Research, Sustainability, System Integration (SI), Team Player, United States Department of Energy (DOE), Writing Skills

LOCATION

Richland, WA

POSTED

16 days ago

**Overview** At PNNL, our core capabilities are divided among major departments that we refer to as Directorates within the Lab, focused on a specific area of scientific research or other function, with its own leadership team and dedicated budget. Our Science & Technology directorates include National Security, Earth and Biological Sciences, Physical and Computational Sciences, and Energy and Environment. In addition, we have an Environmental Molecular Sciences Laboratory, a Department of Energy, Office of Science user facility housed on the PNNL campus. The Earth and Biological Sciences Directorate (EBSD) leads critical research in four areas: Atmospheric, Climate & Earth Sciences, Biological Sciences, Environmental Molecular Sciences, and Global Change. Our vision is to develop a predictive understanding of biological and Earth systems in transition. We aim to understand energy and material flows within the integrated Earth system; to understand, predict, and control the response of biosystems to environmental and/or genomic changes; and to?? Model the Earth system from the subsurface to the atmosphere.? The?Biological Sciences Division?has 17 collaborative, interdisciplinary biology-based teams to tackle major challenges in ecosystem sustainability, bioenergy, human health, and national security. Teams use unique field sites, advanced instrumentation, and integrated computational approaches to explore molecular-scale processes. Strategic efforts focus on advancing molecular measurement capabilities, uncovering the structure and function of molecular dark matter, identifying control points in complex systems, and developing domain-aware AI to accelerate discovery and hypothesis-driven research. **Responsibilities** Pacific Northwest National Laboratory (PNNL) is a world-class research institution powered by a highly educated, diverse workforce committed to collaboration and work-life balance. Every year, scores of dynamic, driven post-docs come to PNNL to work with world-renowned researchers on cutting edge science, innovations, and technologies. The Translation Omics Group at PNNL is seeking a Postdoctoral Research Associate to join our multi-disciplinary team with a focus on mass spectrometry-based lipidomics analysis and LC-MS biomarker development related to type 1 diabetes. The postdoc will be working across multiple cutting-edge NIH-funded projects related to biomedical and clinical applications. The individual will develop and optimize targeted and untargeted LC-MS methods to advance lipidomics profiling capabilities, identify and validate candidate biomarkers, and contribute to type 1 diabetes research. The candidate will have the opportunity to receive technical training in the latest cutting-edge mass spectrometry applications available within PNNL. The selected candidate is expected to: + Have strong expertise in mass spectrometry analytical approaches for omics and biological interpretation, + Develop and validate quantitative LC-MS assays for candidate biomarkers in complex biological matrices (e.g., plasma, serum), + Conduct independent research and work on team assignments, lead manuscripts and maintain a strong overall publication record in the peer-reviewed scientific literature, + Interact, communicate, and problem-solve with a diverse team of multi-disciplinary research staff across PNNL, + Present research projects at national conferences, + Work safely and independently in a laboratory setting, and + Participate in the development of research proposals. An ideal candidate will also have experience in ion mobility spectrometry and bioinformatics pipelines. This is a full-time, limited-term employment position. The duration of this appointment is two years, with the option of extending the appointment for up to three years. **Qualifications** Minimum Qualifications: + Candidates must have received a PhD within the past five years (60 months) or within the next 8 months from an accredited college or university. Preferred Qualifications: + The ideal candidate would have a Ph.D. degree in analytical chemistry, biochemistry, or closely related fields with strong biological knowledge of human metabolism. + Experience with mass spectrometry. + Experience with chromatography (LC-MS) and/or ion mobility spectrometry, and the ability to tackle large, complex omics datasets is desirable but not required. + Additionally, the candidate should be safety-oriented, possess excellent communication skills (oral and written), be collaborative, and have a desire to learn and develop new concepts and research techniques. The ability to critically think, problem-solve, and execute routine research tasks independently is essential. **Hazardous Working Conditions/Environment** The candidate may process samples in a Biosafety Level 2 laboratory. **Testing Designated Position** This is not Testing Designated Position (TDP). **About PNNL** Pacific Northwest National Laboratory (PNNL) is a world-class research institution powered by a highly educated, diverse workforce committed to the values of Integrity, Creativity, Collaboration, Impact, and Courage. Every year, scores of dynamic, driven people come to PNNL to work with renowned researchers on meaningful science, innovations and outcomes for the U.S. Department of Energy and other sponsors; here is your chance to be one of them! At PNNL, you will find an exciting research environment and excellent benefits including health insurance, and flexible work schedules. PNNL is located in eastern Washington State-the dry side of Washington known for its stellar outdoor recreation and affordable cost of living. The Lab's campus is only a 45-minute flight (or ~3 hour drive) from Seattle or Portland, and is serviced by the convenient PSC airport, connected to 8 major hubs. **Commitment to Excellence and Equal Employment Opportunity** Our laboratory is committed to fostering a work environment where all individuals are treated with fairness and respect while solving critical challenges in fundamental sciences, national security, and energy resiliency. We are an Equal Employment Opportunity employer. Pacific Northwest National Laboratory (PNNL) is an Equal Opportunity Employer. PNNL considers all applicants for employment without regard to race, religion, color, sex, national origin, age, disability, genetic information (including family medical history), protected veteran status, and any other status or characteristic protected by federal, state, and/or local laws. We are committed to providing reasonable accommodations for individuals with disabilities and disabled veterans in our job application procedures and in employment. If you need assistance or an accommodation due to a disability, contact us at careers@pnnl.gov . **Drug Free Workplace** PNNL is committed to a drug-free workplace supported by Workplace Substance Abuse Program (WSAP) and complies with federal laws prohibiting the possession and use of illegal drugs. If you are offered employment at PNNL, you must pass a drug test prior to commencing employment. PNNL complies with federal law regarding illegal drug use. Under federal law, marijuana remains an illegal drug. If you test positive for any illegal controlled substance, including marijuana, your offer of employment will be withdrawn. **Security, Credentialing, and Eligibility Requirements** As a national laboratory, PNNL is responsible for adhering to the Homeland Security Presidential Directive 12 (HSPD-12) and Department of Energy (DOE) Order 473.1A, which require new employees to obtain and maintain a HSPD-12 Personal Identify Verification (PIV) Credential. To obtain this credential, new employees must successfully complete the applicable tier of federal background investigation post hire and receive a favorable federal adjudication. The tier of federal background investigation will be determined by job duties and national security or public trust responsibilities associated with the job. All tiers of investigation include a declaration of illegal drug activities, including use, supply, possession, or manufacture within the last 1 to 7 years (depending on the applicable tier of investigation). Illegal drug activities include marijuana and cannabis derivatives, which are still considered illegal under federal law, regardless of state laws. For foreign national candidates: If you have not resided in the U.S. for three consecutive years, you are not eligible for the PIV credential and instead will need to obtain a favorable Local Site Specific Only (LSSO) Federal risk determination to maintain employment. Once you meet the three-year residency requirement thereafter, you will be required to obtain a PIV credential to maintain employment. The tier of federal background investigation required to obtain the PIV credential will be determined by job duties at the time you become eligible for the PIV credential. **Mandatory Requirements** Please be aware that the Department of Energy (DOE) prohibits DOE employees and contractors from having any affiliation with the foreign government of a country DOE has identified as a "country of risk" without explicit approval by DOE and Battelle. If you are offered a position at PNNL and currently have any affiliation with the government of one of these countries, you will be required to disclose this information and recuse yourself of that affiliation or receive approval from DOE and Battelle prior to your first day of employment. **Rockstar Rewards** Employees and their families are offered medical insurance, dental insurance, vision insurance, robust telehealth care options, several mental health benefits, free wellness coaching, health savings account, flexible spending accounts, basic life insurance, disability insurance*, employee assistance program, business travel insurance, tuition assistance, relocation, backup childcare, legal benefits, supplemental parental bonding leave, surrogacy and adoption assistance, and fertility support. Employees are automatically enrolled in our company-funded pension plan* and may enroll in our 401 (k) savings plan with company match*. Employees may accrue up to 120 vacation hours per year and may receive ten paid holidays per year. * Research Associates excluded. **All benefits are dependent upon eligibility. Click Here For Rockstar Rewards (https://careers.pnnl.gov/rockstar-rewards) **Notice to Applicants** PNNL lists the full pay range for the position in the job posting. Starting pay is calculated from the minimum of the pay range and actual placement in the range is determined based on an individual's relevant job-related skills, qualifications, and experience. This approach is applicable to all positions, with the exception of positions governed by collective bargaining agreements and certain limited-term positions which have specific pay rules. As part of our commitment to fair compensation practices, we do not ask for or consider current or past salaries in making compensation offers at hire. Instead, our compensation offers are determined by the specific requirements of the position, prevailing market trends, applicable collective bargaining agreements, pay equity for the position type, and individual qualifications and skills relevant to the performance of the position. **Minimum Salary** USD $69,000.00/Yr. **Maximum Salary** USD $119,100.00/Yr.

About the Company

Pacific Northwest National Laboratory

INDUSTRY

Other/Not Classified