A postdoctoral position focuses on inner ear regeneration and hearing restoration using reprogramming, animal models, and bioengineering approaches.
- Projects include testing new delivery vehicles (viral and non-viral) for inner ear gene, mRNA, and protein delivery with minimal toxicity, and optimizing hair cell regeneration using human organoids.
- The research aims to regenerate diverse inner ear cell types (hair cells, neurons) in adult mice and pigs to restore hearing, building on previous discoveries of mechanisms and molecules promoting regeneration.
- State-of-the-art techniques such as scRNAseq, genome editing, nanoparticle delivery, and functional studies are employed.
- The lab has a successful history in gene therapy, including a pioneering clinical trial restoring hearing in children.
- Candidates should have a Ph.D., M.D./Ph.D., or MD with a strong background in molecular, cellular, genetics, gene editing, and animal models, and a publication record.
- The position offers an exciting opportunity to advance basic research toward translational hearing therapies.