Manager Commercial Production Lab

At GeneDx (Nasdaq: WGS), we don't just diagnose rare diseases - we redefine what's possible in precision

medicine. With one of the world's largest, rare disease datasets, we turn genomic data into answers that change lives

and accelerate discovery. Patients and families around the world are counting on us to lead with bold ideas,

relentless focus, and drive to end the diagnostic odyssey. Visit www.genedx.com to learn how we're making

precision medicine the global standard of care.

Summary

The Manager leads a team within the Commercial Production Lab, providing day-to-day guidance, coaching, and

support to ensure high-quality execution of diagnostic workflows. This role is responsible for fostering team

performance, maintaining a culture of accountability and continuous improvement, and ensuring alignment with

departmental goals. The Manager monitors key performance indicators, supports professional development, and

ensures adherence to standard operating procedures. In collaboration with Functional Leads and cross-functional

partners, the Manager helps drive timely completion of projects and contributes to broader operational success.

Job Responsibilities:

• Directly manages a small group of individual contributors with a primary focus on personnel management.

• Serves as the main point of contact for direct reports within the functional area.

• Conducts regular meetings to address performance, concerns, and development needs.

• Manages employee time-off requests and coordinates with functional leads to ensure adequate coverage.

• Collaborates with training leads to onboard new hires and reinforce team culture, policies, and expectations.

• Discusses performance goals and expectations; gathers feedback and prepares and delivers performance reviews.

• Provides constructive feedback, coaching, and mentoring to support ongoing skill development.

• Identifies training needs and individuals requiring additional support; participates in Performance Improvement Plans and terminations as needed.

• May perform competency assessments.

• Facilitates communication within the team and across functional areas.

• Serves as a key resource for complex cases and questions, applying expert knowledge of processes, policies, genes, tests, and workflows.

• Troubleshoots own cases and supports others in resolving issues.

• Maintains high accuracy and meets workload targets with attention to detail.

• Performs additional duties within validated competency scope and as assigned to support team or departmental needs.

• Credential-specific responsibilities include but are not limited to:

• ABMGG Certified: Fulfill responsibilities of Clinical Consultant as defined by CLIA (42 CFR 493.1457), including:

• Consultation Availability: Provides timely consultation to ordering providers regarding test selection, interpretation, and clinical correlation of laboratory results.

• Report Oversight: Reviews and ensures laboratory reports meet CLIA and CAP requirements for accuracy, completeness, and clinical relevance.

• Result Authorization: Approves and signs off on high-complexity test results in accordance with CLIA regulations.

• If performing clinical patient genetic counseling, maintains Certified Genetic Counselor (CGC) credential through the American Board of Genetic Counseling, Inc. and meets established standards for professional practice.

• Provides genetic counseling via teleconferencing .

• Participates in patient and client communication.

• Supports education and competency training for laboratory staff on genetic counseling principles, regulatory requirements, and best practices.

• Meets or exceeds annual continuing education requirements to maintain professional competency.

• If acting as a lab supervisor as defined by CLIA, CAP, and CLEP or performing genomic analysis, responsibilities include:

• Providing day-to-day supervision or oversight of the laboratory operation and the personnel performing testing.

• Ensuring accessibility at all times - on site, by telephone or by electronic consultation - to resolve technical problems in accordance with policies and procedures.

• Monitoring the performance characteristics of tests and ensuring that acceptable levels of performance are consistently maintained.

• Verifying that personnel are trained prior to performing testing on patient specimens independently.

• Completing staff competency assessments at the appropriate intervals.

• Ensuring action is taken when personnel do not perform as expected.

People Manager

• Yes
• Provides collaborative oversight of a small team, working closely with functional leads

Education, Experience, and Skills

• Degree in Molecular Biology, Genetics, Biotechnology, Genetic Counseling or a related field; PhD in Biology, Genetics or related field; MD or DO with experience in human genetics plus:
• At least 5 years of relevant experience with a Bachelor's degree, including progressive leadership responsibilities.
• At least 2 years of relevant experience with a Master's degree
• At least 1 years of relevant experience with a PhD, MD, or DO
• Demonstrated expertise in clinical diagnostics, with a strong track record of leadership and management in roles of increasing responsibility, including experience at GeneDx or within similarly specialized environments.
• Must maintain above average level of performance in duties with minimal errors. This may include, but is not limited to, demonstrating sustained above average level of performance related to quantity and quality of work being completed, dependability, teamwork, and initiative as expected for responsibilities.
• Excellent writing, communication, and collaboration skills, with strong organizational, time management, and critical thinking abilities.

Certificates, Licenses, Registrations

• For relevant positions, ABMGG Diplomate or equivalent certification in a specialty may be required.
• For Genetic Counselors, Master's degree from an accredited genetic counseling program is required. Certification by the American Board of Genetic Counseling (ABGC) or equivalent is required. Licensure is required in the state where the employee works, if applicable; additional state licenses may be requested based on organizational needs.

Physical Demands

• Prolonged periods of sitting or working at a computer in a home office environment
• Occasional need to lift or move materials or equipment weighing up to 20 pounds during travel or team visits
• For some roles, duties are performed onsite:
• Frequent standing, walking, and movement throughout laboratory and production areas
• Limited use of personal protective equipment (PPE), including lab coats, gloves, and safety goggles
• Occasional lifting, carrying, or movement of lab supplies, reagents, or equipment weighing up to 30 pounds

Work Environment

• Frequent use of digital communication platforms (e.g. video conferencing, email, and collaboration tools).
• Ability to focus and manage complex tasks in a remote setting with multiple concurrent priorities.
• May require occasional travel to laboratory sites, corporate offices, or conferences (typically <10%).
• For some roles, duties are performed onsite:
• Possible contact with water (hand washing and cleaning), biohazardous body fluids, and hazardous chemicals.
• Sufficient noise and interruptions cause distraction and stress.
• The noise level in the work environment is usually moderate.

Acknowledgements

The above job description is not intended to be an all-inclusive list of duties and standards of the position.

Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.

Pay Transparency, Budgeted Range

$110,000-$158,000 USD

~

Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry's genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

A culture that plays to win, because patients are counting on us

At GeneDx, we''re driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day - and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we''re proud to put our names on.

Here's what you can expect day to day:

1. Play like a champion (step up, redefine what's possible, own it)

We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments - with quality, speed, and care.

2. Think bigger (stretch beyond, courage not consensus)

We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls - choosing progress over perfection.

3. Grow fast (be curious, speak up, be agile)

We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.

If you're motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you'll thrive at GeneDx.

Benefits include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Stock Purchase Plan
• Employee Discounts
• Voluntary benefits
• Programs for parents and parents-to-be
• We provide expert support for family planning, pregnancy, and postpartum care, including up to 22 weeks of fully paid parental leave (U.S.) and up to $25K annually for fertility, adoption, or surrogacy.

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.