Lead System Engineer

Title: Lead Design Engineer
Location: Onsite, Pittsburgh, PA 15213
Type: Direct-Hire/Permanent
Hours: Standard business hours
Start: May
Overview: Join a cutting-edge lab to discover novel therapeutics that are seekinga highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments.

Responsibilities:

• Design, prototype, and refine biomedical devices and components supporting advanced experimental system
• Develop and optimize fabrication processes to ensure consistency, quality, and scalability
• Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows
• Perform testing and validation of device performance, including durability, reproducibility, and functional integrity
• Collaborate with scientific and engineering teams to align device design with experimental requirements
• Maintain documentation related to design iterations, fabrication processes, and quality control
• Troubleshoot device-related issues and implement design improvements
• Support coordination of engineering activities across multidisciplinary teams and contribute to project execution
• Contribute to preparation of technical documentation, reports, and related materials

Requirements:

• Bachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field
• Minimum of 3 years of relevant experience in device design, prototyping, or fabrication
• Experience with engineering design tools (e.g., CAD software)
• Strong problem-solving skills and attention to detail
• Ability to work effectively in multidisciplinary research and engineering environments

Preferred Qualifications

• Master’s or Ph.D. in a relevant engineering discipline
• Experience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling
• Familiarity with polymer-based materials and manufacturing processes
• Experience with iterative prototyping and design-for-manufacturing principles
• Experience working at the interface of engineering and biological systems

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