Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Night Shift

Amgen

Holly Springs, NC

JOB DETAILS
SALARY
$106,148–$143,612 Per Year
SKILLS
Administrative Skills, Biotech and Pharmaceutical, Budgeting, Coaching, Code of Federal Regulations, Continuous Improvement, Current Good Manufacturing Practice (cGMP), Drug Products, Identify Issues, Lean Manufacturing, Maintain Compliance, Manufacturing Management, Manufacturing Operations, Mentoring, Process Improvement, Regulations, Safety Compliance, Safety/Work Safety, Set Goals, Sustainability, Team Lead/Manager
LOCATION
Holly Springs, NC
POSTED
1 day ago

This role is a Night Shift Manager in manufacturing, overseeing 24/7 biotech drug substance production in a state-of-the-art facility with advanced technology and sustainability initiatives.

  • Lead and manage teams of manufacturing associates on a 12-hour rotation, ensuring safety, compliance, and production goals.
  • Champion a culture of continuous improvement, Lean principles, and regulatory adherence, including cGMP and CFR standards.
  • Develop staff through coaching, training, and mentorship, while fostering a safe, respectful work environment.
  • Collaborate across functions to optimize processes, troubleshoot issues, and implement CAPAs.
  • Support administrative tasks such as budgeting and goal setting.

  • Qualifications include a relevant advanced degree and managerial experience in manufacturing or operations, with preferred biotech or pharmaceutical industry knowledge.

    Compensation ranges from $106,148 to $143,612, with comprehensive benefits and growth opportunities.

About the Company

A

Amgen

At Amgen, we believe in a “biology first” approach. We use cutting-edge science and technology to study the subtlest biological mechanisms in search of therapies that will improve the lives of those who suffer from serious diseases. Amgen believes the cure for disease can be found inside each and every one of us.
COMPANY SIZE
10,000 employees or more
INDUSTRY
Biotechnology/Pharmaceuticals
WEBSITE
http://www.amgen.com