The Director, Investor Relations & External Communications will play a critical role in shaping how Cabaletta Bio is understood by the investment community and external stakeholders during a period of significant value creation. Responsibilities: Strategic Leadership Develop and execute an integrated investor relations and external communications strategy aligned with Cabaletta Bio's corporate milestones, including BLA submission and commercialization readiness. Partner with executive leadership to shape, refine, and consistently communicate Cabaletta Bio's investment thesis and corporate narrative. Serve as a trusted advisor to the CFO, CBO, and CEO on messaging, positioning, and engagement with the investment community. Build scalable processes and infrastructure to support Cabaletta Bio's evolution into a commercial-stage organization. Investor Relations Serve as a primary point of contact for investors and analysts, fostering strong, long-term relationships across the investment community. Lead preparation of earnings materials, investor presentations, and key external communications. Support capital markets activities, including financings, investor targeting, and roadshows. Monitor market dynamics, peer landscape, analyst coverage, and investor sentiment to inform strategy and leadership decision-making. Provide ongoing insights to executive leadership regarding valuation drivers and investor expectations. Track and schedule investor interactions and provide insights into future interactions. External Communications Own and ensure consistency of messaging across all external channels, including press releases, investor materials, and corporate content. Translate complex clinical, regulatory, and scientific developments into clear, accessible, and compelling narratives. Support communications related to clinical milestones, regulatory interactions, and business development activities. Partner with external agencies to enhance Cabaletta Bio's visibility and ensure alignment of messaging. Support executive visibility, conference participation, and thought leadership opportunities. Cross-Functional Collaboration Work closely with Clinical, Regulatory, R&D, Commercial, and Business Development teams to ensure alignment between internal progress and external messaging. Support preparation for investor meetings, earnings calls, and key external engagements. Ensure consistent, thoughtful communication during critical inflection points, including clinical readouts and regulatory milestones. Qualifications: