Cell and Gene Therapy Technician

Job DescriptionResponsibilities:• Help with operational start-up of a new CART process development lab space• Participate in information/ tech transfer from external collaborator and implementation of CART processing technologies (T-cell isolation, activation, genome-engineering, expansion, cryopreservation, and supporting/ associated analytical characterization methods)• Contribute to relevant and impactful innovation programs to enhance CART manufacturing technologies/ capabilities and work-processes (such as alternate transfection/ cell engineering strategies, media development, disposable/ closed production systems and automation) as needed/ appropriate.• Process development for manufacturing of cell- or gene-therapies• T cell molecular biology/ engineering and characterization of primary T cells• Molecular virology/ engineering and production of recombinant viruses• Mammalian cell genome engineering• Development of analytical methods for characterization of cell-based or gene-therapies – experience with cell-based and flow-cytometry-based assays for characterization of cell populations and/ or activityOr• PhD degree in Molecular Immunology/ Molecular Biology or related field or Chem.•

Cell And Gene Therapy TechnicianA Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.Job DescriptionResponsibilities:• Help with operational start-up of a new CART process development lab space• Participate in information/ tech transfer from external collaborator and implementation of CART processing technologies (T-cell isolation, activation, genome-engineering, expansion, cryopreservation, and supporting/ associated analytical characterization methods)• Contribute to relevant and impactful innovation programs to enhance CART manufacturing technologies/ capabilities and work-processes (such as alternate transfection/ cell engineering strategies, media development, disposable/ closed production systems and automation) as needed/ appropriate.• Apply scientific and technical experience to establish safe, high-quality lab practices, and demonstrate strong personal leadership and technical and interpersonal skills• Ensure high-quality, timely documentation in electronic laboratory notebooks and contribute to and Technical Reports as appropriate.QualificationsQualifications and skills needed:• Degree in Molecular Immunology/ Molecular Biology or related field or Chem.• Engineering degree (with appropriate Cell and Gene Therapy focus) with relevant laboratory experience (BSc +5 years/ MSc +3 years), preferably in biotech/ biopharma industry.• Process development for manufacturing of cell- or gene-therapies• T cell molecular biology/ engineering and characterization of primary T cells• Molecular virology/ engineering and production of recombinant viruses• Mammalian cell genome engineering• Development of analytical methods for characterization of cell-based or gene-therapies – experience with cell-based and flow-cytometry-based assays for characterization of cell populations and/ or activityOr• PhD degree in Molecular Immunology/ Molecular Biology or related field or Chem.• Engineering degree (with appropriate Cell and Gene Therapy focus) with 4+ years of postgraduate experience (or MSc with 7+ years) in biotech/ biopharma industry (preferably in the development and characterization of manufacturing processes for cell- or gene-based therapies).• T cell molecular biology/ engineering and characterization of primary T cells• Molecular virology/ engineering and production of recombinant viruses• Mammalian cell genome engineering• Development of analytical methods for characterization of cell-based or gene-therapies – experience with cell-based and flow-cytometry-based assays for characterization of cell populations and/ or activity