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Bench Scientist - II

Aequor Technologies LLC

Cambridge, MA

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JOB DETAILS
SKILLS
Analysis Skills, Automation, Biochemistry, Biology, Biomedicine, Biotech and Pharmaceutical, Cell Cultures, Communication Skills, DNA, Data Analysis, Database Management Software/Systems (DBMS), Detail Oriented, Documentation, GMP (Good Manufacturing Practices), High Throughput, Identify Issues, Instrumentation, Inventory Management, Laboratory, Laboratory Information Management System (LIMS), Laboratory Notebook, Maintain Compliance, Molecular Biology, Multitasking, Next Generation Sequencing (NGS), Nucleic Acid, Organizational Skills, Pre-Clinical, Process Improvement, Production Schedule, Production Support, Project/Program Management, Python Programming/Scripting Language, Quality Control, Quantitative Analysis, Record Keeping, Research Laboratory, Safety Compliance, Specimens/Samples, Team Player, Testing, Time Management, Workflow Analysis
LOCATION
Cambridge, MA
POSTED
2 days ago
Role Summary
*** s BioMedicine Design (BMD) is seeking a highly motivated Biochemist/Molecular Biologist to join Biotherapeutic Expression and Purification group (BEP) in Cambridge, MA. Qualified candidate will play an essential role in a high-energy DNA production and protein expression research laboratory. The group supports non-GMP transient protein lead production across *** s diverse biotherapeutic discovery portfolio to enable *** s research units and their pre-clinical therapeutic in-vitro and in-vivo needs. The BEP DNA production and protein expression group is looking for a laboratory technician to provide DNA production support for the protein expression and purification activities in BEP. The candidate is expected to have a strong background in molecular biology techniques and experience with nucleic acid production and analysis. The successful candidate will grow bacterial cultures and perform large-scale DNA production activities following standardized protocols. The candidate will be a key contributor to the scientific team responsible for protein expression and purification.
Role Responsibilities
Independently execute high-throughput plasmid DNA production workflows including bacterial culture, plasmid purification, and downstream sample handling
Operate and troubleshoot automated instrumentation including Biotage, Opentrons, and related liquid handling platforms
Perform DNA quality control testing including gel electrophoresis, nucleic acid quantification, purity assessment, and endotoxin testing
Prepare and submit samples for next-generation sequencing (NGS) and support basic data review of sequencing results
Manage plasmid DNA inventory, sample storage, and tracking within electronic databases and sample management systems
Maintain accurate records in an electronic lab notebook and ensure documentation compliance
Collaborate with expression and purification scientists to ensure timely DNA delivery for downstream workflows
Contribute to process improvements to enhance throughput, reproducibility, and cycle time
Communicate progress, priorities, and risks to meet production schedules and deadlines
Qualifications
Education
B.S. in Biological Sciences, Molecular Biology, Biotechnology, Biochemistry, or a related life sciences discipline
Required
2+ years experience with molecular biology techniques including plasmid preparation, nucleic acid purification, and quantitative DNA analysis
2+ years experience with bacterial cell culture systems
Proficiency in DNA QC methods including gel electrophoresis and sample preparation for sequencing
Experience operating automated or semi-automated lab instrumentation
Strong organizational skills with the ability to manage multiple projects in a high-throughput setting
Proficiency with electronic lab notebooks and sample tracking systems
Attention to detail during repetitive, high-volume tasks
Strong communication and teamwork skills
Commitment to laboratory safety and compliance
Preferred
Experience with NGS library preparation or sequencing workflows
Familiarity with Python scripting for data analysis or workflow automation
Experience with plate-based (96/384-well) high-throughput workflows
Familiarity with LIMS or sample management platforms (e.g., FreezerPro, Genedata)

About the Company

A

Aequor Technologies LLC

COMPANY SIZE
100 to 499 employees
INDUSTRY
Staffing/Employment Agencies

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