Associate Scientist, In Vivo Pharmacology

• Lead in vivo PK/PD model development or execution including biospecimen collection, processing, and analyses.
• Serve as study monitor or study lead for IND-enabling studies performed in-house.
• Write and amend IACUC protocols and internal SOPs as necessary.
• Liaise with vivarium staff as necessary.
• Oversee animal vendors, CROs, and diagnostic labs to ensure timely completion of non-GLP in vivo studies.
• Participate in all aspects of vivarium and lab operation, training, and compliance including external audits where applicable.
• Other duties and responsibilities as assigned.

• Bachelors degree with a minimum of 8 years of experience or Masters degree with a minimum of 6 years of experience in Immunology or other relevant life sciences (2 years must be in biotech or industry setting).
• Familiarity with animal handling, survival blood draws (lateral tail vein, facial/maxilliary/submandibular), terminal blood draws (cardiac puncture), and dosing methods including i.v., s.c., i.p., and p.o. a must.
• Independently execute immune models in relevant rodent species including but not limited to type 1 diabetes, colitis, lupus, rheumatoid arthritis, and multiple sclerosis.
• Experience running GSP/”GLP-like” studies suitable for regulatory submissions including gross necropsy and tissue preparations for histopathology.
• Nice to have:
  • Knowledge of surgical techniques including transplantation and portal vein infusion 
  • Experience with common bioanalytical methods such as Ligand binding assays, flow cytometry
  • Experience writing study reports
• Excellent oral, written communication, and presentation skills.
• Demonstrated ability to effectively work in cross-functional teams, meet deadlines, and prioritize multiple projects is required.
• Comfortable working collaboratively in a small, fast-paced environment.
• Ability to quickly adjust to shifting project demands and priorities.

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