Scientist III

Job Title: Scientist III
Location: Ridgefield, CT
Type: Contract
Compensation: $47.83
Contractor Work Model: Onsite
Hours: 40 hours per week

Overview
Leading pharmaceutical company looking for an experienced Scientist III. Ideal candidates should have a Masters degree with at least 6 years of experience in molecular, cell biology, or related scientific discipline.

Responsibilities

• Design, develop, and execute functional genomics assays, including CRISPR-based editing (e.g., RNP delivery, Perturb-seq), single-cell sequencing, spatial transcriptomics, and CITE-seq.
• Provide technical guidance and training to research scientists on FGSL technologies and techniques, including assay execution, troubleshooting, and resolution of technical issues.
• Document and maintain detailed laboratory records in accordance with policies.
• Operate and maintain lab equipment in collaboration with other lab members.
• Assist in the acquisition of necessary supplies and equipment.
• Define and perform appropriate quality control measures.
• Follow relevant scientific literature to ensure use of optimal methods and stay current with emerging practices across the field.
• Demonstrate the ability to interpret experimental outcomes, propose appropriate follow-up actions, and suggest new avenues of investigation.
• Communicate work effectively both orally and in writing.
• Contribute to writing protocols, procedures, and technical reports.
• Automate processing and results reporting/delivery.
• Report and handle data with integrity and ethics.

Requirements

• Minimum 2 years of CRISPR experience with designing guides, performing transfections/infections, selecting edited cells, and validating knockouts/knock-ins.
• Proficiency in molecular biology techniques such as qPCR, Western blot, cloning, and gel electrophoresis.
• Experience in cell culture, maintaining multiple cell lines, and sterile techniques.
• Hands-on experience with next-generation sequencing (NGS), including library preparation and quality control.
• Knowledge of single-cell technologies, sample prep, and library generation.
• Ability to troubleshoot experiments both independently and in a team environment.
• Excellent oral and written communication skills.
• Education: Master’s degree in molecular, cell biology, or a related scientific discipline with at least 6+ years of relevant experience.