Research Scientist, Cell Biology – T Cell Biology
Artech LLC
Santa Monica, CA
JOB DETAILS
SALARY
$68–$71.42 Per Hour
LOCATION
Santa Monica, CA
POSTED
7 days ago
Location: Santa Monica CA
Duration: 12+ Months
Pay Range: $68/hr - $71.42
Client is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) cell therapies designed to empower the immune system's ability to recognize and kill tumors.
Discovery Research is seeking a highly motivated Research Scientist to lead characterization studies that address product efficacy and safety. The successful candidate will report to a Director and will be expected to independently design and perform experiments, organize and analyze results, and communicate and present findings in team meetings.
Responsibilities
Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development or support combination strategies to enhance T cell product potency and safety
Experimental design aimed to address basic tumor immunology aspects related to the immunosuppressive tumor microenvironment
Genetic/biochemical manipulation of T cells and evaluation of impact on T cell function
Analyze, organize and communicate results at different research and cross-functional meetings
Plan and effectively execute experiments based on strategy, project timelines and goals
Analyze and present scientific results to the project team in addition to cross-functional and cross-site audiences
Document experimental results to enable subsequent clinical studies and patent applications
May serve as a core team member or leader on a project team
Work effectively with other functions (including Process Development, Translational Medicine, Clinical Development) to ensure alignment cross-functionally
Coordinate tasks across multiple projects, demonstrating prioritization and planning
May mentor junior team members and supervise the work of a research team including, but not limited to, organizing and prioritizing laboratory work and review of generated experimental results
Basic Qualifications
Advanced scientific degree (i.e. MD, PharmD, PhD)
OR
Masters Degree and 6+ years of scientific experience
Preferred Qualifications
Experience designing and developing primary immune cell assays using key immune cell populations
Hands-on expertise in T-cell functional characterization assays including in vitro Cytotoxicity, proliferation, cytokine/chemokine measurements, cell signaling, activation, differentiation and exhaustion
Proficient in cell culture aseptic technique
Proficient in multi-parameter flow cytometry (panel design, sample acquisition, data processing) and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel)
Experience with MSD/ELISA and/or Luminex
Ph.D. degree in biology-related field (immunology, cellular and/or tumor biology or a closely related field)
A strong background in cancer immunotherapy and human immunology, experience working with engineered T cells strongly preferred
Demonstrated independence in experimental design, data analysis, interpretation, and presentation
Maintain a high degree of accuracy and attention to detail
Drive to learn and make a meaningful impact
Comfortable in a fast-paced company environment with minimal direction and able to adjust workload based upon changing priorities
Strong collaboration, excellent interpersonal and communication skills
Experience using both written and verbal communication, including presentations, to communicate results to a diverse cross-functional audience
Strong organizational and record keeping skills
Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description
Client is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors.
About the Company
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