Lead Engineer
System One
Pittsburgh, Pennsylvania
Title: Lead Engineer
Location: Onsite, Pittsburgh, PA 15213
Type: Direct-Hire/Permanent
Hours: Standard business hours
Start: May
Overview:
Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the design, development, integration, and optimization of advanced engineering systems used in complex experimental environments. This role combines device development, fluidic and instrumentation system integration, and process optimization to enable reliable, reproducible, and scalable experimental platforms. The position will contribute to both early-stage prototyping and system-level implementation across multidisciplinary applications.
Responsibilities:
- Design, prototype, and refine devices, components, and system architectures for experimental platforms
- Develop and optimize fabrication, assembly, and integration processes to ensure quality, consistency, and scalability
- Design and implement fluidic systems, including flow control networks, pumps, valves, and routing architectures
- Support development of controlled system environments (e.g., airflow, fluid flow, or dynamic operating conditions)
- Integrate mechanical, fluidic, and instrumentation systems into cohesive, multi-component platforms
- Perform system testing, validation, and performance characterization to ensure reliability and reproducibility
- Troubleshoot technical issues and implement solutions to improve system robustness and efficiency
- Contribute to material selection, manufacturing methods, and design-for-manufacturing strategies
- Maintain detailed documentation including design specifications, system configurations, SOPs, and validation data
- Collaborate with cross-functional teams to align engineering solutions with application and operational needs
- Support preparation of technical reports, documentation, and project deliverables
Requirements:
- Bachelor’s degree in Engineering (Mechanical, Biomedical, Electrical, Systems, or related field)
- Minimum of 3+ years of experience in engineering design, system integration, or experimental platform development
- Experience with prototyping, hardware systems, or device development
- Experience with fluid systems, instrumentation, or process control environments
- Strong analytical, troubleshooting, and problem-solving skills
- Ability to work effectively in multidisciplinary teams
Preferred Qualifications
- Advanced degree (Master’s or Ph.D.) in a relevant engineering discipline
- Experience with complex, multi-component system integration
- Familiarity with fabrication techniques (e.g., precision machining, molding, or small-scale device manufacturing)
- Experience with fluid handling systems, microfluidics, or flow control applications
- Experience with sensors, data acquisition systems, or automated control platforms
- Knowledge of design-for-manufacturing and scalability principles
- Experience working in regulated or controlled environments
- Experience at the interface of engineering and biological or experimental systems
#M3
#LI-KM2
Ref: #558-Scientific
About the Company
System One
Every day, System One focuses on services and solutions that require a high degree of specialization, in-demand technical skills, and large-scale operational expertise. We are essential partners to those on the front lines of our nation’s most critical infrastructure, technology, and life sciences initiatives.
Founded more than 40 years ago as a staffing partner to the engineering industry, today System One is a diversified organization operating in over 50 locations and putting more than 9,000 people to work in the United States, Canada, and the United Kingdom.