Immunology Principal Research Associate
Vertex Pharmaceuticals Incorporated
Seattle, WA
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JOB DETAILS
JOB TYPE
Full-time, Employee
SKILLS
Analysis Skills, Analysis Software, Assays, Biology, Biotech and Pharmaceutical, Detail Oriented, Experiment Design, Identify Issues, Immunology, Legal, Microsoft Office, Multitasking, Nucleic Acid, Organizational Skills, Polymerase Chain Reaction (PCR), Prism, Real-time PCR (qPCR), Team Player
LOCATION
Seattle, WA
POSTED
30+ days ago
General Summary:
The discovery immunology research team isseekinga highly motivatedPrincipal Research Associate.This is a laboratory-based role wherethe successful candidate will contribute directlytoresearch efforts by designing, executing, and analyzing experiments related to immune mechanisms, target validation, and therapeutic development.The position requiresstrong attention to detail and ability to multitask while working in a highly collaborative environment.
Key Duties and Responsibilities:
Isolate, culture, and manipulate primary human immune cells and cell lines.
Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays.
Troubleshoot experiments and optimize protocols.
Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records.
Collaborate with scientists across discovery teams to achieve project goals.
Prepare data for internal reports and presentations for internal meetings.
Perform other duties as needed.
Knowledge and Skills:
Hands-on tissue culture experience, including the isolation and maintenance of primary human immune cells and human cell lines.
Experience with nucleic acid techniques to quantify gene expression such as PCR, qPCR, and RNA sequencing.
Experience with a variety of cell-based immunology assays to interrogate immune cell phenotype and function including multicolor flow cytometry and Incucyte assays.
Experience measuring soluble analytes such as by ELISA, Luminex, or MSD.
Critical thinking and self-reliance to solve tasks independently or ask questions.
Strong organizational skills and attention to detail.
Willingness and ability to work in a highly collaborative environment.
Foundational knowledge of immunology and an eagerness to learn new techniques and skills.
Strong analytical skills and proficiency in the following software packages: Microsoft Office, GraphPad Prism, FlowJo and Methodical Mind Analysis Software.
Education and Experience:
Master's degree (or equivalent degree) in biological sciences and 2+ years of relevant employment experience, or
Bachelor's Degree (or equivalent degree) in biological sciences and 5+ years of relevantemployment experience
Pay Range:
$92,900 - $139,300
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Human Resources at ApplicationAssistance@vrtx.com.
About the Company
V
Vertex Pharmaceuticals Incorporated
Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases. Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and commercial offices in the United States, Europe, Canada and Australia. For six years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the company, please visit www.vrtx.com
COMPANY SIZE
5,000 to 9,999 employeesINDUSTRY
Biotechnology/Pharmaceuticals
FOUNDED
1989
WEBSITE
https://www.vrtx.com/